Gene Page:PCGF6

Summary?
GeneID 84108
Symbol PCGF6
Synonyms MBLR|RNF134
Description polycomb group ring finger 6
Reference MIM:607816|HGNC:HGNC:21156|Ensembl:ENSG00000156374|HPRD:07427|Vega:OTTHUMG00000018982
Gene type protein-coding
Map location 10q24.33
Pascal p-value 6.469E-4
Sherlock p-value 0.418
Fetal beta 0.65
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
LK:YES Genome-wide Association Study This data set included 99 genes mapped to the 22 regions. The 24 leading SNPs were also included in CV:Ripke_2013

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs6536929 0 PCGF6 84108 0.11 trans
rs3752278 chr20 37050816 PCGF6 84108 0.17 trans
rs788350 chr20 37064635 PCGF6 84108 0.18 trans
rs1303567 chr20 37106156 PCGF6 84108 0.05 trans
rs805554 chr20 37107040 PCGF6 84108 0.09 trans
rs1303577 chr20 37125856 PCGF6 84108 0.17 trans
rs1303575 chr20 37128816 PCGF6 84108 0.17 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13- 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
LIU SOX4 TARGETS DN 309 191 All SZGR 2.0 genes in this pathway
WANG LMO4 TARGETS DN 352 225 All SZGR 2.0 genes in this pathway
GINESTIER BREAST CANCER 20Q13 AMPLIFICATION DN 180 101 All SZGR 2.0 genes in this pathway
COLDREN GEFITINIB RESISTANCE UP 85 57 All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800 473 All SZGR 2.0 genes in this pathway
SHETH LIVER CANCER VS TXNIP LOSS PAM1 229 137 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE EARLY LATE 317 190 All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882 538 All SZGR 2.0 genes in this pathway