Gene Page:USMG5

Summary?
GeneID 84833
Symbol USMG5
Synonyms DAPIT|HCVFTP2|bA792D24.4
Description up-regulated during skeletal muscle growth 5 homolog (mouse)
Reference MIM:615204|HGNC:HGNC:30889|Ensembl:ENSG00000173915|HPRD:18277|Vega:OTTHUMG00000018984
Gene type protein-coding
Map location 10q24.33
Pascal p-value 0.003
Fetal beta -1.173
eGene Myers' cis & trans
元
Support G2Cdb.humanPSD
G2Cdb.humanPSP

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1
LK:YES Genome-wide Association Study This data set included 99 genes mapped to the 22 regions. The 24 leading SNPs were also included in CV:Ripke_2013

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg04165840 10 105156204 USMG5;PDCD11 4.025E-4 -0.183 0.044 DMG:Wockner_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs7088711 chr10 104559265 USMG5 84833 2.538E-5 cis
rs2482506 chr10 104563742 USMG5 84833 8.631E-7 cis
rs4919690 chr10 104616499 USMG5 84833 0.11 cis
rs4409766 chr10 104616662 USMG5 84833 0.1 cis
rs3740393 chr10 104636654 USMG5 84833 0.05 cis
rs3740390 chr10 104638479 USMG5 84833 0.08 cis
rs12413409 chr10 104719095 USMG5 84833 0.01 cis
rs17115419 chr10 104834875 USMG5 84833 0.07 cis
rs11191560 chr10 104869037 USMG5 84833 0.03 cis
rs1163249 chr10 104909889 USMG5 84833 2.722E-4 cis
rs7913461 chr10 105001324 USMG5 84833 2.327E-10 cis
rs1891292 chr10 105001509 USMG5 84833 1.026E-9 cis
rs1163073 chr10 105022933 USMG5 84833 1.494E-21 cis
rs10883855 chr10 105092446 USMG5 84833 0 cis
rs11191686 chr10 105187745 USMG5 84833 2.788E-8 cis
rs11191688 chr10 105192569 USMG5 84833 4.714E-5 cis
rs7088711 chr10 104559265 USMG5 84833 0 trans
rs2482506 chr10 104563742 USMG5 84833 1.634E-4 trans
rs1163249 chr10 104909889 USMG5 84833 0.02 trans
rs7913461 chr10 105001324 USMG5 84833 5.737E-8 trans
rs1891292 chr10 105001509 USMG5 84833 2.536E-7 trans
rs1163073 chr10 105022933 USMG5 84833 2.272E-19 trans
rs11191686 chr10 105187745 USMG5 84833 6.526E-6 trans
rs11191688 chr10 105192569 USMG5 84833 0.01 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
WAMUNYOKOLI OVARIAN CANCER LMP UP 265 158 All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER GRADES 1 2 UP 137 84 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK DN 79 54 All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800 473 All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957 597 All SZGR 2.0 genes in this pathway
CAFFAREL RESPONSE TO THC 24HR 5 DN 59 35 All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266 171 All SZGR 2.0 genes in this pathway
JIANG AGING HYPOTHALAMUS UP 47 31 All SZGR 2.0 genes in this pathway
KRIEG KDM3A TARGETS NOT HYPOXIA 208 107 All SZGR 2.0 genes in this pathway