Gene Page:AJUBA

Summary?
GeneID 84962
Symbol AJUBA
Synonyms JUB
Description ajuba LIM protein
Reference MIM:609066|HGNC:HGNC:20250|Ensembl:ENSG00000129474|HPRD:16426|Vega:OTTHUMG00000028711
Gene type protein-coding
Map location 14q11.2
Pascal p-value 0.002
Fetal beta 1.57

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DNM:Guipponi_2014 Whole Exome Sequencing analysis 49 DNMs were identified by comparing the exome of 53 individuals with sporadic SCZ and of their non-affected parents

Section I. Genetics and epigenetics annotation

@DNM table

Gene Chromosome Position Ref Alt Transcript AA change Mutation type Sift CG46 Trait Study
AJUBA T G NM_032876 p.L284L synonymous NA NA Schizophrenia DNM:Guipponi_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0005515 protein binding IEA -
GO:0005215 transporter activity IEA -
GO:0008270 zinc ion binding IEA -
GO:0046872 metal ion binding IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0007155 cell adhesion IEA -
GO:0007049 cell cycle IEA -
GO:0048041 focal adhesion formation IEA -
GO:0006810 transport IEA -
GO:0043087 regulation of GTPase activity IEA -
GO:0030334 regulation of cell migration IEA -
GO:0035313 wound healing, spreading of epidermal cells IEA -
GO:0030032 lamellipodium biogenesis IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005813 centrosome IEA -
GO:0005856 cytoskeleton IEA -
GO:0005634 nucleus IEA -
GO:0005737 cytoplasm IEA -
GO:0030027 lamellipodium IEA -
GO:0005925 focal adhesion IEA -
GO:0005886 plasma membrane IEA -
GO:0030054 cell junction IEA -

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-148/152 1015 1022 1A,m8 hsa-miR-148a UCAGUGCACUACAGAACUUUGU
hsa-miR-152brain UCAGUGCAUGACAGAACUUGGG
hsa-miR-148b UCAGUGCAUCACAGAACUUUGU
miR-17-5p/20/93.mr/106/519.d 1507 1513 m8 hsa-miR-17-5p CAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ CAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519d CAAAGUGCCUCCCUUUAGAGUGU
miR-182 1354 1361 1A,m8 hsa-miR-182 UUUGGCAAUGGUAGAACUCACA
miR-24 1019 1026 1A,m8 hsa-miR-24SZ UGGCUCAGUUCAGCAGGAACAG
miR-539 854 860 1A hsa-miR-539 GGAGAAAUUAUCCUUGGUGUGU
miR-9 141 147 1A hsa-miR-9SZ UCUUUGGUUAUCUAGCUGUAUGA