SZGR2 - Beplay体育中心

Summary?

基因ID	857
象征	CAV1
同义词	BSCL3\|CGL3\|LCCNS\|MSTP085\|PPH3\|VIP21
描述	caveolin 1
参考	MIM：601047\|HGNC:HGNC:1527\|Ensembl:ENSG00000105974\|HPRD:03028\|Vega：Otthumg0000000023413
基因类型	protein-coding
Map location	7q31.1
Pascal P值	0.592
Fetal beta	0.013

基因in Data Sources

基因set name	基因组方法	描述	Info
简历：PGCNP	Genome-wide Association Study	GWAS
PMID:cooccur	高通量文献搜索	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
文学	高通量文献搜索	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias	点击to show details
GO_Annotation	Mapping neuro-related keywords to Gene Ontology annotations	与神经相关的关键字的命中：1
Network	Shortest path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 0.5838

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

基因ral gene expression (GTEx)

Devlopment期间的基因表达（BrainCloud）

脚注：
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

基因expression of temporal and spatial changes (BrainSpan)

脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

Top 10 positively co-expressed genes
基因	皮尔逊的相关性	斯皮尔曼的相关性
IL17RA	0.67	0.45
NFATC2	0.64	0.55
LINGO3	0.61	0.29
ADCY5	0.60	0.43
Otof	0.60	0.39
ITGB2	0.60	0.67
PMEPA1	0.59	0.43
SH3D20	0.59	0.42
ENTPD3	0.59	0.36
GPR52	0.59	0.34

前10个负共表达基因
基因	皮尔逊的相关性	斯皮尔曼的相关性
AL139819.3	-0.28	-0.35
RP9P	-0.27	-0.39
AC120053.1	-0.24	-0.30
Sycp3	-0.24	-0.32
AC010300.1	-0.24	-0.29
NOX1	-0.23	-0.25
AC087071.1	-0.22	-0.20
FAM159B	-0.22	-0.37
AF347015.21	-0.22	-0.23
SPDYA	-0.22	-0.27

Section III. Gene Ontology annotation

Molecular function	去的术语	Evidence	Neuro keywords	PubMed ID
GO:0005515	protein binding	IPI		16951145
去：0005198	structural molecule activity	IDA		11865038
GO:0016504	protease activator activity	ISS		-
GO:0015485	cholesterol binding	TAS		11294831
GO:0050998	nitric-oxide synthase binding	IPI		12852865
Biological process	去的术语	Evidence	Neuro keywords	PubMed ID
GO:0007519	skeletal muscle development	ISS	神经元（GO期限：8）	-
GO:0000188	inactivation of MAPK activity	ISS		-
GO:0001570	血管生成	ISS		-
去：0001666	对缺氧的反应	ISS		-
GO:0001937	negative regulation of endothelial cell proliferation	ISS		-
GO:0016050	囊泡组织	IDA		12743374
GO:0052547	调节肽酶活性	ISS		-
GO:0008104	蛋白质定位	ISS		-
去:0019915	脂质的隔离	ISS		-
GO:0006816	calcium ion transport	ISS		-
GO:0006940	regulation of smooth muscle contraction	ISS		-
GO:0006641	triacylglycerol metabolic process	ISS		-
GO:0006897	内吞作用	ISS		-
GO:0006874	细胞钙离子稳态	ISS		-
去：0030193	regulation of blood coagulation	IMP		17848177
GO：0033484	一氧化氮稳态	ISS		-
GO:0051260	protein homooligomerization	ISS		-
GO:0030857	negative regulation of epithelial cell differentiation	ISS		-
GO:0019217	regulation of fatty acid metabolic process	ISS		-
GO:0030301	cholesterol transport	TAS		11294831
GO:0043409	MAPKKK级联的负调节	ISS		-
GO：0042632	胆固醇稳态	TAS		11294831
GO：0045907	positive regulation of vasoconstriction	ISS		-
GO：0045908	negative regulation of vasodilation	ISS		-
去：0045019	negative regulation of nitric oxide biosynthetic process	ISS		-
GO:0046426	JAK-STAT级联的负调节	ISS		-
GO：0048554	positive regulation of metalloenzyme activity	ISS		-
GO：0060056	乳腺对合	ISS		-
GO:0051899	膜去极化	ISS		-
细胞分量	去的术语	Evidence	Neuro keywords	PubMed ID
去：0000139	高尔基膜	经验		14707126
去：0000139	高尔基膜	IDA		11294831
去：0000139	高尔基膜	国际能源机构		-
GO:0005794	高尔基体	国际能源机构		-
去：0005811	lipid particle	经验		9188442\|9580552\|10781589 \|16722822\|16807357
GO:0005783	endoplasmic reticulum	IDA		11294831
GO:0016020	membrane	国际能源机构		-
GO:0016021	integral to membrane	国际能源机构		-
GO:0005901	caveola	IDA		15219854
GO:0005886	plasma membrane	国际能源机构		-
GO:0005887	质膜的积分	TAS		1360410
GO:0048471	细胞质的核周区	ISS		-

Section IV. Protein-protein interaction annotation

互动者	别名b	官方全名b	Experimental	来源	PubMed ID
ADRBK1	BARK1 \| BETA-ARK1 \| FLJ16718 \| GRK2	肾上腺素，β，受体激酶1	Reconstituted Complex	BioGRID	10085129
AKAP1	Akap \|AKAP121 \|AKAP149 \|AKAP84 \|d-akap1 \|MGC1807 \|prka1 \|sakap84	A kinase (PRKA) anchor protein 1	-	HPRD	11546661
应用程序	AAA \| ABETA \| ABPP \| AD1 \| APPI \| CTFgamma \| CVAP \| PN2	amyloid beta (A4) precursor protein	-	HPRD,BioGRID	9553108
aqp3	GIL	Aquaporin 3（Gill Blood Group）	Affinity Capture-Western	BioGRID	14675200
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	-	HPRD,BioGRID	11278309
AR	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	androgen receptor	Caveolin-1与AR相互作用。	BIND	11278309
BMX	ETK \| PSCTK2 \| PSCTK3	BMX非受体酪氨酸激酶	-	HPRD,BioGRID	11751885
BST1	CD157	bone marrow stromal cell antigen 1	-	HPRD	11866528
BTK	AGMX1 \| AT \| ATK \| BPK \| IMD1 \| MGC126261 \| MGC126262 \| PSCTK1 \| XLA	Bruton agammaglobulinemia tyrosine kinase	-	HPRD,BioGRID	11751885
CAV1	CAV \| MSTP085 \| VIP21	caveolin 1, caveolae protein, 22kDa	CAV1 (caveolin-1) homodimerizes.	BIND	15782218
CAV2	CAV \| MGC12294	caveolin 2	-	HPRD,BioGRID	9361015\|12414992
CDH1	弧1 \|CD324 \|cdhe \|ECAD \|lcam \|UVO	钙粘蛋白1，1型，e-钙粘蛋白（上皮）	E-钙黏着蛋白与小窝蛋白1相互作用。	BIND	14706341
CSK	MGC117393	c-src tyrosine kinase	-	HPRD,BioGRID	11805080
dag1	156DAG \| A3a \| AGRNR \| DAG	多糖1（肌营养不良蛋白相关的糖蛋白1）	Reconstituted Complex	BioGRID	11724572
EDNRB	abcds \|ETB \|etbr \|ETRB \|HSCR \|HSCR2	内皮素受体型B型	-	HPRD,BioGRID	12694195
EGFR	ERBB \|ERBB1 \|her1 \|PIG61 \|梅纳	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	-	HPRD,BioGRID	9374534
ERBB2	CD340 \|her-2 \|her-2/neu \|her2 \|neu \|ngl \|TKR1	V-ERB-B2红细胞白血病病毒性癌基因同源2，神经/胶质母细胞瘤衍生的癌基因同源物（Avian）	-	HPRD	9685399
ESR1	DKFZP686N23123 \|er \|ESR \|Esra \|时代\|NR3A1	雌激素受体1	-	HPRD,BioGRID	11563984
FLNA	ABP-280 \|ABPX \|DKFZP434P031 \|fln \|fln1 \|FMD \|MNS \|NHBP \|OPD \|OPD1 \| OPD2	filamin A, alpha (actin binding protein 280)	-	HPRD	10637311
FLOT1	-	flotillin 1	Affinity Capture-Western	BioGRID	10212252
flot2	ECS-1 \|ECS1 \|ESA \|esa1 \|M17S1	flotillin 2	-	HPRD,BioGRID	10212252
GJA1	CX43 \|DFNB38 \|Gjal \|奇数	gap junction protein, alpha 1, 43kDa	-	HPRD,BioGRID	11980479
GJA3	CX46 \|czp3	间隙连接蛋白，Alpha 3，46KDA	-	HPRD,BioGRID	11980479
GJB2	CX26 \| DFNA3 \| DFNB1 \| HID \| KID \| NSRD1 \| PPK	gap junction protein, beta 2, 26kDa	-	HPRD,BioGRID	11980479
GRK1	GPRK1 \| RHOK \| RK	G蛋白偶联受体激酶1	Reconstituted Complex	BioGRID	10085129
GRK5	GPRK5	G蛋白偶联受体激酶5	Reconstituted Complex	BioGRID	10085129
ILK	DKFZp686F1765 \| P59	整联蛋白连接激酶	ILK1与小窝蛋白-1相互作用。	BIND	15722199
insr	CD220 \| HHF5	胰岛素受体	-	HPRD,BioGRID	10598578
购物中心	BENE \| MGC4419	mal, T-cell differentiation protein-like	-	HPRD	1294831
NEU3	FLJ12388 \|sial3	sialidase 3 (membrane sialidase)	-	HPRD,BioGRID	12011038
NGFR	CD271 \| Gp80-LNGFR \| TNFRSF16 \| p75(NTR) \| p75NTR	nerve growth factor receptor (TNFR superfamily, member 16)	Reconstituted Complex	BioGRID	9867838
NOS2	HEP-NOS \| INOS \| NOS \| NOS2A	nitric oxide synthase 2, inducible	-	HPRD,BioGRID	11114180
NOS3	ecnos \|eNOS	一氧化氮合酶3（内皮细胞）	-	HPRD,BioGRID	8910295
NTRK1	DKFZP781I14186 \|MTC \|trk \|trk1 \|trka \|p140-trka	neurotrophic tyrosine kinase, receptor, type 1	-	HPRD,BioGRID	9867838
PDGFRA	CD140A \| MGC74795 \| PDGFR2 \| Rhe-PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	Affinity Capture-Western Co-fractionation Reconstituted Complex	BioGRID	10066366
PDGFRB	CD140B \|JTK12 \|PDGF-R-BETA \|PDGFR \|PDGFR1	platelet-derived growth factor receptor, beta polypeptide	Affinity Capture-Western Co-fractionation Reconstituted Complex	BioGRID	10066366
PLD2	-	phospholipase D2	-	HPRD,BioGRID	10675563
PPP1CA	MGC15877 \| MGC1674 \| PP-1A \| PPP1A	protein phosphatase 1, catalytic subunit, alpha isoform	CAV1与PP1-C交互。	BIND	14645548
PRKACA	MGC102831 \| MGC48865 \| PKACA	protein kinase, cAMP-dependent, catalytic, alpha	Affinity Capture-Western	BioGRID	11546661
PRNP	ASCR \| CD230 \| CJD \| GSS \| MGC26679 \| PRIP \| PrP \| PrP27-30 \| PrP33-35C \| PrPc \| prion	prion protein	-	HPRD	10988071
PTEN	10q23del \|BZS \|MGC11227 \|姆姆\|mmac1 \|pten1 \|tep1	phosphatase and tensin homolog	-	HPRD,BioGRID	12176037
PTEN	10q23del \|BZS \|MGC11227 \|姆姆\|mmac1 \|pten1 \|tep1	phosphatase and tensin homolog	caveolin-1 interacts with PTEN.	BIND	12176037
PTGS2	COX-2 \|cox2 \|Gripghs \|PGG/HS \|PGHS-2 \|PHS-2 \|HCOX-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	-	HPRD,BioGRID	11432874
PTPN1	ptp1b	蛋白质酪氨酸磷酸酶，非受体1型	caveolin-1 interacts with PTP1B.	BIND	12176037
PTPN1	ptp1b	蛋白质酪氨酸磷酸酶，非受体1型	-	HPRD,BioGRID	12176037
PTPN11	bptp3 \|CFC \|MGC14433 \|NS1 \|PTP-1D \|PTP2C \|SH-PTP2 \|sh-ptp3 \|SHP2	蛋白质酪氨酸磷酸酶，非受体1型1	-	HPRD,BioGRID	12176037
PTPN11	bptp3 \|CFC \|MGC14433 \|NS1 \|PTP-1D \|PTP2C \|SH-PTP2 \|sh-ptp3 \|SHP2	蛋白质酪氨酸磷酸酶，非受体1型1	caveolin-1 interacts with SH-PTP2.	BIND	12176037
PTPN6	HCP \| HCPH \| HPTP1C \| PTP-1C \| SH-PTP1 \| SHP-1 \| SHP-1L \| SHP1	蛋白质酪氨酸磷酸酶，非受体6型	-	HPRD,BioGRID	12176037
PTPN6	HCP \| HCPH \| HPTP1C \| PTP-1C \| SH-PTP1 \| SHP-1 \| SHP-1L \| SHP1	蛋白质酪氨酸磷酸酶，非受体6型	caveolin-1 interacts with PTP-1C.	BIND	12176037
PTPRF	FLJ43335 \|FLJ45062 \|FLJ45567 \|拉尔	protein tyrosine phosphatase, receptor type, F	-	HPRD,BioGRID	12176037
PTPRF	FLJ43335 \|FLJ45062 \|FLJ45567 \|拉尔	protein tyrosine phosphatase, receptor type, F	Caveolin-1与LAR相互作用。	BIND	12176037
rcvrn	RCV1	recoverin	-	HPRD,BioGRID	12507501
S1PR1	Chedg1 \|D1S3362 \|ECGF1 \|EDG-1 \|EDG1 \|FLJ58121 \|S1P1	鞘氨醇1-磷酸受体1	-	HPRD,BioGRID	10921915
SCP2	DKFZP686C12188 \|DKFZP686D11188 \|NLTP \|NSL-TP \|SCPX	sterol carrier protein 2	Affinity Capture-Western 烦恼 Two-hybrid	BioGRID	15182174
Smad2	JV18 \| JV18-1 \| MADH2 \| MADR2 \| MGC22139 \| MGC34440 \| hMAD-2 \| hSMAD2	SMAD family member 2	Co-fractionation	BioGRID	11102446
SRC	ASV \|src1 \|C-SRC \|P60-SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	-	HPRD,BioGRID	8910575
Stoml3	Epb7.2l \| SRO	stomatin (EPB72)-like 3	-	HPRD	12122055
STRN	MGC125642 \| SG2NA	striatin, calmodulin binding protein	-	HPRD	11707266
strn4	FLJ35594 \| ZIN \| zinedin	纹状体，钙调蛋白结合蛋白4	-	HPRD	11707266
TGFBR1	AAT5 \| ACVRLK4 \| ALK-5 \| ALK5 \| LDS1A \| LDS2A \| SKR4 \| TGFR-1	转化生长因子，β受体1	-	HPRD,BioGRID	11102446
TNFRSF1B	CD120B \|tbpii \|TNF-R-II \|TNF-R75 \|tnfbr \|tnfr1b \|TNFR2 \|TNFR80 \|P75 \|P75TNFR	肿瘤坏死因子受体超家族，成员1b	-	HPRD,BioGRID	11112773
传统	HS.89862 \|MGC11078	通过死亡域与TNFRSF1A相关	-	HPRD,BioGRID	11112773
traf2	MGC:45012 \| TRAP \| TRAP3	TNF受体相关因子2	-	HPRD,BioGRID	11112773\|11805080
TRPC1	HTRP-1 \|MGC133334 \|MGC133335 \|TRP1	瞬态受体电位阳离子通道，亚家族C，成员1	Affinity Capture-Western	BioGRID	10980191
TSC2	FLJ43106 \| LAM \| TSC4	结节硬化2	Co-purification	BioGRID	12147258

Section V. Pathway annotation

路径名	Pathway size	＃szgr 2.0基因	Info
KEGG FOCAL ADHESION	201	138	All SZGR 2.0 genes in this pathway
KEGG VIRAL MYOCARDITIS	73	58	All SZGR 2.0 genes in this pathway
BIOCARTA NO1 PATHWAY	33	24	All SZGR 2.0 genes in this pathway
Biocarta整联蛋白途径	38	29	All SZGR 2.0 genes in this pathway
ST INTEGRIN SIGNALING PATHWAY	82	62	All SZGR 2.0 genes in this pathway
PID胰岛素途径	45	32	All SZGR 2.0 genes in this pathway
PID PTP1B PATHWAY	52	40	All SZGR 2.0 genes in this pathway
pid wnt典型途径	20	18	All SZGR 2.0 genes in this pathway
PID TNF PATHWAY	46	33	All SZGR 2.0 genes in this pathway
PID P53下游途径	137	94	All SZGR 2.0 genes in this pathway
PID ALK1 PATHWAY	26	21	All SZGR 2.0 genes in this pathway
PID PDGFRA PATHWAY	22	18	All SZGR 2.0 genes in this pathway
PID VEGFR1 PATHWAY	26	23	All SZGR 2.0 genes in this pathway
PID VEGFR1 2 PATHWAY	69	57	All SZGR 2.0 genes in this pathway
PID TGFBR途径	55	38	All SZGR 2.0 genes in this pathway
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	91	65	All SZGR 2.0 genes in this pathway
REACTOME ENOS ACTIVATION AND REGULATION	20	14	All SZGR 2.0 genes in this pathway
REACTOME BASIGIN INTERACTIONS	30	23	All SZGR 2.0 genes in this pathway
脂质和脂蛋白的反应组代谢	478	302	All SZGR 2.0 genes in this pathway
REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	13	11	All SZGR 2.0 genes in this pathway
REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	46	37	All SZGR 2.0 genes in this pathway
REACTOME HEMOSTASIS	466	331	All SZGR 2.0 genes in this pathway
PYEON HPV阳性肿瘤DN	10	5	All SZGR 2.0 genes in this pathway
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL UP	285	181	All SZGR 2.0 genes in this pathway
刘前列腺癌DN	481	290	All SZGR 2.0 genes in this pathway
Onken紫菜叶黑色素瘤DN	526	357	All SZGR 2.0 genes in this pathway
Bertucci髓质与导管乳腺癌DN	169	118	All SZGR 2.0 genes in this pathway
PAX FOXO1融合的Davicioni目标	255	177	All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN	69	43	All SZGR 2.0 genes in this pathway
乳腺癌腔与基础DN	455	304	All SZGR 2.0 genes in this pathway
乳腺癌腔与间充质DN	460	312	All SZGR 2.0 genes in this pathway
Laiho结直肠癌锯齿状	112	71	All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS UP	290	177	All SZGR 2.0 genes in this pathway
NUP98 HOXA9 Fusion 3D的Takeda目标	182	110	All SZGR 2.0 genes in this pathway
NUP98 HOXA9 Fusion 10D的Takeda目标	194	122	All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 1 DN	242	165	All SZGR 2.0 genes in this pathway
SENESE HDAC1 AND HDAC2 TARGETS DN	232	139	All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP	1278	748	All SZGR 2.0 genes in this pathway
SCIBETTA KDM5B TARGETS DN	81	55	All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA UP	171	112	All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA BY DMOG UP	130	85	All SZGR 2.0 genes in this pathway
ELVIDGE HIF1A TARGETS DN	91	58	All SZGR 2.0 genes in this pathway
Elvidge HIF1A和HIF2A靶向DN	104	72	All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER LMP DN	199	124	All SZGR 2.0 genes in this pathway
WAMUNYOKOLI OVARIAN CANCER GRADES 1 2 DN	67	43	All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN	1375	806	All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP	128	95	All SZGR 2.0 genes in this pathway
kokkinakis甲硫氨酸剥夺96小时	117	84	All SZGR 2.0 genes in this pathway
MARKEY RB1 ACUTE LOF DN	228	137	All SZGR 2.0 genes in this pathway
阿霉素DN的Graessmann凋亡	1781	1082	All SZGR 2.0 genes in this pathway
CAIRO PML TARGETS BOUND BY MYC DN	14	12	All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA DN	394	258	All SZGR 2.0 genes in this pathway
KERLEY RESPONSE TO CISPLATIN UP	44	30	All SZGR 2.0 genes in this pathway
MISSIAGLIA REGULATED BY METHYLATION DN	122	67	All SZGR 2.0 genes in this pathway
MIDORIKAWA AMPLIFIED IN LIVER CANCER	55	38	All SZGR 2.0 genes in this pathway
Lindgren膀胱癌簇2B	392	251	All SZGR 2.0 genes in this pathway
WANG METHYLATED IN BREAST CANCER	35	25	All SZGR 2.0 genes in this pathway
Martoriati MDM4靶向胎儿肝	227	137	All SZGR 2.0 genes in this pathway
GRUETZMANN PANCREATIC CANCER UP	358	245	All SZGR 2.0 genes in this pathway
inamura肺癌SCC DN	14	6	All SZGR 2.0 genes in this pathway
WATTEL AUTONOMOUS THYROID ADENOMA DN	55	29	All SZGR 2.0 genes in this pathway
SASAI RESISTANCE TO NEOPLASTIC TRANSFROMATION	50	31	All SZGR 2.0 genes in this pathway
GROSS ELK3 TARGETS UP	27	16	All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA HIF1A DN	110	78	All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS DN	848	527	All SZGR 2.0 genes in this pathway
Guenther生长球形与辅助DN	26	19	All SZGR 2.0 genes in this pathway
BERTUCCI INVASIVE CARCINOMA DUCTAL VS LOBULAR DN	46	34	All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY DN	110	64	All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR UP	176	115	All SZGR 2.0 genes in this pathway
KOYAMA SEMA3B TARGETS DN	411	249	All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS	988	594	All SZGR 2.0 genes in this pathway
罗斯急性我ELOID LEUKEMIA CBF	82	57	All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS B LYMPHOCYTE UP	78	51	All SZGR 2.0 genes in this pathway
SASAKI ADULT T CELL LEUKEMIA	176	122	All SZGR 2.0 genes in this pathway
ROSS AML WITH AML1 ETO FUSION	76	55	All SZGR 2.0 genes in this pathway
ZHANG TARGETS OF EWSR1 FLI1 FUSION	88	68	All SZGR 2.0 genes in this pathway
LEI MYB TARGETS	318	215	All SZGR 2.0 genes in this pathway
HADDAD B LYMPHOCYTE PROGENITOR	293	193	All SZGR 2.0 genes in this pathway
CROMER METASTASIS DN	81	58	All SZGR 2.0 genes in this pathway
NPM1突变DN的Verhaak AML	246	180	All SZGR 2.0 genes in this pathway
Yagi AML Fab标记	191	131	All SZGR 2.0 genes in this pathway
REN ALVEOLAR RHABDOMYOSARCOMA DN	408	274	All SZGR 2.0 genes in this pathway
WANG SMARCE1 TARGETS DN	371	218	All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 24HR DN	148	102	All SZGR 2.0 genes in this pathway
Lindvall通过Tert Up永生	78	48	All SZGR 2.0 genes in this pathway
Simbulan Parp1靶向	31	23	All SZGR 2.0 genes in this pathway
LU AGING BRAIN UP	262	186	All SZGR 2.0 genes in this pathway
JIANG HYPOXIA NORMAL	311	205	All SZGR 2.0 genes in this pathway
MCDOWELL ACUTE LUNG INJURY DN	48	33	All SZGR 2.0 genes in this pathway
Tracey对IFNA2 DN的抗性	32	23	All SZGR 2.0 genes in this pathway
Creighton内分泌疗法抗性1	528	324	All SZGR 2.0 genes in this pathway
HARRIS BRAIN CANCER PROGENITORS	44	23	All SZGR 2.0 genes in this pathway
促进耐受巨噬细胞DN	409	268	All SZGR 2.0 genes in this pathway
SAGIV CD24 TARGETS UP	23	15	All SZGR 2.0 genes in this pathway
SAGIV CD24 TARGETS DN	46	26	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B DN	564	326	All SZGR 2.0 genes in this pathway
Smid乳腺癌正常	476	285	All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING	510	309	All SZGR 2.0 genes in this pathway
ZHENG GLIOBLASTOMA PLASTICITY DN	58	39	All SZGR 2.0 genes in this pathway
LABBE WNT3A TARGETS UP	112	71	All SZGR 2.0 genes in this pathway
LABBE TGFB1 TARGETS DN	108	64	All SZGR 2.0 genes in this pathway
HUANG DASATINIB RESISTANCE UP	81	53	All SZGR 2.0 genes in this pathway
MATTHEWS AP1 TARGETS	17	12	All SZGR 2.0 genes in this pathway
泰勒在急性淋巴细胞白血病中甲基化	77	52	All SZGR 2.0 genes in this pathway
ALONSO METASTASIS UP	198	128	All SZGR 2.0 genes in this pathway
Ruiz TNC靶向DN	142	79	All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS DN	435	289	All SZGR 2.0 genes in this pathway
SHAFFER IRF4 TARGETS IN MYELOMA VS MATURE B LYMPHOCYTE	101	76	All SZGR 2.0 genes in this pathway
浆细胞与成熟B淋巴细胞中的Shaffer IRF4靶标	67	51	All SZGR 2.0 genes in this pathway
SHAFFER IRF4 TARGETS IN ACTIVATED B LYMPHOCYTE	81	66	All SZGR 2.0 genes in this pathway
SHAFFER IRF4 TARGETS IN ACTIVATED DENDRITIC CELL	65	49	All SZGR 2.0 genes in this pathway
Zhan晚分化基因上升	33	24	All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 13	30	20	All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION	368	247	All SZGR 2.0 genes in this pathway
LI PROSTATE CANCER EPIGENETIC	30	22	All SZGR 2.0 genes in this pathway
DANG REGULATED BY MYC DN	253	192	All SZGR 2.0 genes in this pathway
黄成人组织茎模块	721	492	All SZGR 2.0 genes in this pathway
Hirsch细胞转化特征dn	103	67	All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS GROWING	243	155	All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS CONFLUENT	567	365	All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE	1137	655	All SZGR 2.0 genes in this pathway
PASINI SUZ12 TARGETS DN	315	215	All SZGR 2.0 genes in this pathway
DELPUECH FOXO3 TARGETS UP	68	49	All SZGR 2.0 genes in this pathway
BMI1和PCGF2的Wiederschain目标	57	39	All SZGR 2.0 genes in this pathway
Smad2或Smad3的Koinuma目标	824	528	All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN	784	464	All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE VIA P38 COMPLETE	227	151	All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL UP	489	314	All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族	目标位置			mirna id	miRNA seq
mirna家族	UTR start	UTR end	Match method	mirna id	miRNA seq
miR-124/506	655	661	M8	HSA-MIR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	655	661	M8	hsa-miR-124^脑	UAAGGCACGCGGUGAAUGCC
mir-142-5p	1665年	1671年	1a	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
mir-17-5p/20/93.mr/106/519.D	1522	1528	1a	HSA-MIR-17-5P	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^脑	UAAAGUGCUUAUAGUGCAGGUAG
				HSA-MIR-106A	AAAAGUGCUUACAGUGCAGGUAGC
				HSA-MIR-106B^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	caaagugcuugugcagguag
				hsa-miR-519d	caaagugccucccuuuagugugu
miR-199	1573	1579	M8	HSA-MIR-199A	CCCAGUGUUCAGACUACCUGUUC
miR-199	1573	1579	M8	HSA-MIR-199B	cccaguguuuagacuaucuuc
miR-204/211	396	402	1a	hsa-miR-204^脑	Uucccuuugucauccuaugccu
miR-204/211	396	402	1a	hsa-miR-211	uucccuuugucauccuucgccu
miR-30-3p	1615年	1622	1a,m8	hsa-miR-30a-3p	cuuucagucggauguugcagc
miR-30-3p	1615年	1622	1a,m8	hsa-miR-30e-3p	cuuucagucggauguauacagc
miR-431	1727	1733	1a	hsa-miR-431	UGUCUUGCAGGCCGUCAUGCA
miR-505	286	292	1a	HSA-MIR-505	GUCAACACUUGCUGGUUUCCUC
miR-96	55	61	M8	hsa-miR-96^脑	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click这里to see the list of SZ related miRNAs.
大脑：基于miRNA微阵列表达研究在大脑中表达的miRNA。点击这里to see the list of brain related miRNAs.

基因Page:CAV1