Gene Page:OR6A2
Summary?
| GeneID | 8590 |
| Symbol | OR6A2 |
| Synonyms | I7|OR11-55|OR6A1|OR6A2P |
| Description | olfactory receptor family 6 subfamily A member 2 |
| Reference | MIM:608495|HGNC:HGNC:15301|Ensembl:ENSG00000184933|HPRD:09771|Vega:OTTHUMG00000165736 |
| Gene type | protein-coding |
| Map location | 11p15 |
| Pascal p-value | 0.03 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ACSBG1 | 0.93 | 0.92 |
| ALDH2 | 0.90 | 0.88 |
| NDRG2 | 0.90 | 0.90 |
| GPR37L1 | 0.89 | 0.88 |
| PBXIP1 | 0.89 | 0.92 |
| SLC25A18 | 0.89 | 0.86 |
| S1PR1 | 0.88 | 0.89 |
| ALDH1L1 | 0.88 | 0.89 |
| SCARA3 | 0.88 | 0.85 |
| HADHB | 0.87 | 0.89 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RTF1 | -0.61 | -0.71 |
| C6orf168 | -0.60 | -0.64 |
| SPATS2 | -0.59 | -0.66 |
| PHF14 | -0.59 | -0.72 |
| MLLT11 | -0.59 | -0.65 |
| SUPV3L1 | -0.59 | -0.69 |
| MED19 | -0.58 | -0.65 |
| STRBP | -0.58 | -0.66 |
| PARP2 | -0.58 | -0.62 |
| PPP3CC | -0.58 | -0.67 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG嗅觉传导 | 389 | 85 | All SZGR 2.0 genes in this pathway |
| REACTOME SIGNALING BY GPCR | 920 | 449 | All SZGR 2.0 genes in this pathway |
| REACTOME OLFACTORY SIGNALING PATHWAY | 328 | 60 | All SZGR 2.0 genes in this pathway |
| REACTOME GPCR DOWNSTREAM SIGNALING | 805 | 368 | All SZGR 2.0 genes in this pathway |
| YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
| PEDRIOLI MIR31 TARGETS DN | 418 | 245 | All SZGR 2.0 genes in this pathway |