Gene Page:MYH13
Summary?
| GeneID | 8735 |
| Symbol | MYH13 |
| Synonyms | MyHC-IIL|MyHC-eo |
| Description | myosin, heavy chain 13, skeletal muscle |
| Reference | MIM:603487|HGNC:HGNC:7571|Ensembl:ENSG00000006788|HPRD:04599|Vega:OTTHUMG00000177987 |
| Gene type | protein-coding |
| Map location | 17p13 |
| Pascal p-value | 0.547 |
| Fetal beta | -0.169 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | 系统的搜索in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZC3H18 | 0.93 | 0.92 |
| PHF21A | 0.93 | 0.93 |
| DHX38 | 0.93 | 0.93 |
| SF1 | 0.93 | 0.93 |
| C4orf8 | 0.92 | 0.93 |
| SFRS15 | 0.92 | 0.93 |
| SART3 | 0.92 | 0.92 |
| NUMA1 | 0.92 | 0.89 |
| UNK | 0.92 | 0.92 |
| CASC3 | 0.92 | 0.88 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.72 | -0.82 |
| MT-CO2 | -0.70 | -0.82 |
| IFI27 | -0.70 | -0.81 |
| C5orf53 | -0.69 | -0.72 |
| HIGD1B | -0.68 | -0.82 |
| FXYD1 | -0.66 | -0.77 |
| AF347015.27 | -0.66 | -0.77 |
| AF347015.33 | -0.65 | -0.75 |
| MT-CYB | -0.65 | -0.76 |
| AF347015.21 | -0.64 | -0.83 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG TIGHT JUNCTION | 134 | 86 | All SZGR 2.0 genes in this pathway |
| KEGG VIRAL MYOCARDITIS | 73 | 58 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS DN | 357 | 212 | All SZGR 2.0 genes in this pathway |
| MANALO HYPOXIA UP | 207 | 145 | All SZGR 2.0 genes in this pathway |