基因页：NAPG
概括？
| 基因 | 8774 |
| 象征 | NAPG |
| 同义词 | 伽马纳普 |
| 描述 | NSF附着蛋白伽玛 |
| 参考 | MIM：603216|HGNC：HGNC：7642|ENSEMBL：ENSG00000134265|HPRD：04448|Vega：Otthumg00000179119 |
| 基因类型 | 蛋白质编码 |
| 地图位置 | 18p11.22 |
| Pascal P值 | 0.604 |
| Sherlock P值 | 0.957 |
| 胎儿β | -0.419 |
| DMG | 1（＃研究） |
| 主持人 | 尾状基底神经节 小脑半球 小脑 伏隔核基底神经节 梭子基底神经节 迈尔斯的顺式和跨性别 |
| 支持 | 胞吞作用 g2cdb.humanpsd G2CDB.HUMANPSP COMPOSITESET |
数据源中的基因
| 基因集名称 | 基因组方法 | 描述 | 信息 |
|---|---|---|---|
| 简历：PGCNP | 全基因组协会研究 | GWAS | |
| DMG：JAFFE_2016 | 全基因组DNA甲基化分析 | 该数据集包括与SZ患者相关的2,104个探针/CPG（n = 108），而在Bonferroni调整后的P <0.05时，其中136个对照。 | 1 |
| PMID：cooccur | 高通量文献搜索 | PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。 | |
| 文学 | 高通量文献搜索 | 与精神分裂症关键词共同存在：精神分裂症，精神分裂症 | 点击显示详细信息 |
第一节遗传学和表观遗传学注释
差异甲基化基因
差异甲基化基因| 探测 | 染色体 | 位置 | 最近的基因 | p（dis） | beta（dis） | fdr（dis） | 学习 |
|---|---|---|---|---|---|---|---|
| CG01442193 | 18 | 10526432 | NAPG | 1.87E-9 | -0.016 | 1.58e-6 | DMG：JAFFE_2016 |
EQTL注释
| SNP ID | 染色体 | 位置 | 主持人 | Gene Entrez ID | PVALUE | QVALUE | TSS距离 | EQTL类型 |
|---|---|---|---|---|---|---|---|---|
| RS10915848 | CHR1 | 225788919 | NAPG | 8774 | 0.13 | 反式 | ||
| RS9659310 | CHR1 | 246014672 | NAPG | 8774 | 0.06 | 反式 | ||
| RS12997903 | CHR2 | 1952083 | NAPG | 8774 | 0.11 | 反式 | ||
| RS6733654 | CHR2 | 1963270 | NAPG | 8774 | 0.01 | 反式 | ||
| RS2551328 | CHR2 | 23984746 | NAPG | 8774 | 0.1 | 反式 | ||
| RS2551329 | CHR2 | 23984991 | NAPG | 8774 | 0.1 | 反式 | ||
| RS2712089 | CHR2 | 24080273 | NAPG | 8774 | 0 | 反式 | ||
| RS17029291 | CHR3 | 32402138 | NAPG | 8774 | 5.629E-4 | 反式 | ||
| RS16870339 | CHR5 | 2705169 | NAPG | 8774 | 0.07 | 反式 | ||
| RS4617108 | CHR7 | 49423831 | NAPG | 8774 | 0.02 | 反式 | ||
| RS7864672 | Chr9 | 31068069 | NAPG | 8774 | 0.1 | 反式 | ||
| RS4607971 | Chr10 | 19407890 | NAPG | 8774 | 0.04 | 反式 | ||
| RS12873765 | CHR13 | 40039651 | NAPG | 8774 | 0.2 | 反式 | ||
| RS10492735 | CHR13 | 40040035 | NAPG | 8774 | 0.2 | 反式 | ||
| RS1324669 | CHR13 | 107872446 | NAPG | 8774 | 0.01 | 反式 | ||
| RS1761450 | CHR19 | 54818034 | NAPG | 8774 | 0.16 | 反式 | ||
| RS6032293 | CHR20 | 44175130 | NAPG | 8774 | 0.08 | 反式 | ||
| RS9637082 | CHR21 | 21213235 | NAPG | 8774 | 0.14 | 反式 | ||
| RS12157904 | CHR22 | 37982011 | NAPG | 8774 | 0.15 | 反式 | ||
| RS3185480 | 18 | 10487918 | NAPG | ENSG00000134265.8 | 7.506E-7 | 0 | -37984 | gtex_brain_putamen_basal |
| RS1045584 | 18 | 10488091 | NAPG | ENSG00000134265.8 | 6.06e-7 | 0 | -37811 | gtex_brain_putamen_basal |
| RS505893 | 18 | 10488739 | NAPG | ENSG00000134265.8 | 1.842E-6 | 0 | -37163 | gtex_brain_putamen_basal |
| RS593078 | 18 | 10489013 | NAPG | ENSG00000134265.8 | 1.788E-6 | 0 | -36889 | gtex_brain_putamen_basal |
| RS12961978 | 18 | 10489380 | NAPG | ENSG00000134265.8 | 6.989E-7 | 0 | -36522 | gtex_brain_putamen_basal |
| RS653575 | 18 | 10491281 | NAPG | ENSG00000134265.8 | 2.995E-7 | 0 | -34621 | gtex_brain_putamen_basal |
| RS529749 | 18 | 10491304 | NAPG | ENSG00000134265.8 | 3.017E-7 | 0 | -34598 | gtex_brain_putamen_basal |
| RS500222 | 18 | 10491441 | NAPG | ENSG00000134265.8 | 3.125E-7 | 0 | -34461 | gtex_brain_putamen_basal |
| RS397819136 | 18 | 10492051 | NAPG | ENSG00000134265.8 | 5.934e-7 | 0 | -33851 | gtex_brain_putamen_basal |
| RS638170 | 18 | 10492401 | NAPG | ENSG00000134265.8 | 9.621E-8 | 0 | -33501 | gtex_brain_putamen_basal |
| RS577418 | 18 | 10492748 | NAPG | ENSG00000134265.8 | 1.552E-6 | 0 | -33154 | gtex_brain_putamen_basal |
| RS11080425 | 18 | 10493077 | NAPG | ENSG00000134265.8 | 5.64e-7 | 0 | -32825 | gtex_brain_putamen_basal |
| RS2197166 | 18 | 10493908 | NAPG | ENSG00000134265.8 | 5.64e-7 | 0 | -31994 | gtex_brain_putamen_basal |
| RS397858995 | 18 | 10496069 | NAPG | ENSG00000134265.8 | 6.356E-7 | 0 | -29833 | gtex_brain_putamen_basal |
| RS12608388 | 18 | 10496456 | NAPG | ENSG00000134265.8 | 6.323E-7 | 0 | -29446 | gtex_brain_putamen_basal |
| RS16974630 | 18 | 10499123 | NAPG | ENSG00000134265.8 | 6.331E-7 | 0 | -26779 | gtex_brain_putamen_basal |
| RS12953337 | 18 | 10505276 | NAPG | ENSG00000134265.8 | 5.927E-8 | 0 | -20626 | gtex_brain_putamen_basal |
| RS7230144 | 18 | 10505584 | NAPG | ENSG00000134265.8 | 1.106E-6 | 0 | -20318 | gtex_brain_putamen_basal |
| RS148837492 | 18 | 10506086 | NAPG | ENSG00000134265.8 | 2.659E-8 | 0 | -19816 | gtex_brain_putamen_basal |
| RS500029 | 18 | 10506209 | NAPG | ENSG00000134265.8 | 2.858e-7 | 0 | -19693 | gtex_brain_putamen_basal |
| RS8091430 | 18 | 10506375 | NAPG | ENSG00000134265.8 | 5.584e-7 | 0 | -19527 | gtex_brain_putamen_basal |
| RS492820 | 18 | 10507342 | NAPG | ENSG00000134265.8 | 2.159E-6 | 0 | -18560 | gtex_brain_putamen_basal |
| RS201121659 | 18 | 10507963 | NAPG | ENSG00000134265.8 | 1.012E-6 | 0 | -17939 | gtex_brain_putamen_basal |
| RS542735 | 18 | 10507964 | NAPG | ENSG00000134265.8 | 1.008e-6 | 0 | -17938 | gtex_brain_putamen_basal |
| RS8096132 | 18 | 10507965 | NAPG | ENSG00000134265.8 | 8.242e-7 | 0 | -17937 | gtex_brain_putamen_basal |
| RS563331 | 18 | 10512626 | NAPG | ENSG00000134265.8 | 1.544E-6 | 0 | -13276 | gtex_brain_putamen_basal |
| RS71360245 | 18 | 10512959 | NAPG | ENSG00000134265.8 | 1.806E-6 | 0 | -12943 | gtex_brain_putamen_basal |
| RS62093530 | 18 | 10513001 | NAPG | ENSG00000134265.8 | 1.497E-6 | 0 | -12901 | gtex_brain_putamen_basal |
| RS645477 | 18 | 10513242 | NAPG | ENSG00000134265.8 | 1.295E-6 | 0 | -12660 | gtex_brain_putamen_basal |
| RS520666 | 18 | 10515294 | NAPG | ENSG00000134265.8 | 9.364e-8 | 0 | -10608 | gtex_brain_putamen_basal |
| RS522344 | 18 | 10515849 | NAPG | ENSG00000134265.8 | 9.776E-8 | 0 | -10053 | gtex_brain_putamen_basal |
| RS11873815 | 18 | 10517366 | NAPG | ENSG00000134265.8 | 4.447E-8 | 0 | -8536 | gtex_brain_putamen_basal |
| RS473938 | 18 | 10520290 | NAPG | ENSG00000134265.8 | 1.492E-7 | 0 | -5612 | gtex_brain_putamen_basal |
| RS473877 | 18 | 10520309 | NAPG | ENSG00000134265.8 | 3.724e-7 | 0 | -5593 | gtex_brain_putamen_basal |
| RS11663028 | 18 | 10521975 | NAPG | ENSG00000134265.8 | 3.333e-8 | 0 | -3927 | gtex_brain_putamen_basal |
| RS485375 | 18 | 10523143 | NAPG | ENSG00000134265.8 | 7.187E-7 | 0 | -2759 | gtex_brain_putamen_basal |
| RS589573 | 18 | 10523149 | NAPG | ENSG00000134265.8 | 3.778E-7 | 0 | -2753 | gtex_brain_putamen_basal |
| RS588608 | 18 | 10523388 | NAPG | ENSG00000134265.8 | 3.78e-7 | 0 | -2514 | gtex_brain_putamen_basal |
| RS200496690 | 18 | 10523465 | NAPG | ENSG00000134265.8 | 9.754e-8 | 0 | -2437 | gtex_brain_putamen_basal |
| RS482540 | 18 | 10523466 | NAPG | ENSG00000134265.8 | 6.734E-8 | 0 | -2436 | gtex_brain_putamen_basal |
| RS574860 | 18 | 10523467 | NAPG | ENSG00000134265.8 | 6.734E-8 | 0 | -2435 | gtex_brain_putamen_basal |
| RS573168 | 18 | 10523612 | NAPG | ENSG00000134265.8 | 7.192E-7 | 0 | -2290 | gtex_brain_putamen_basal |
| RS578369 | 18 | 10523767 | NAPG | ENSG00000134265.8 | 7.202E-7 | 0 | -2135 | gtex_brain_putamen_basal |
| RS550223 | 18 | 10523811 | NAPG | ENSG00000134265.8 | 7.204E-7 | 0 | -2091 | gtex_brain_putamen_basal |
| RS544553 | 18 | 10524453 | NAPG | ENSG00000134265.8 | 1.223E-7 | 0 | -1449 | gtex_brain_putamen_basal |
| RS649777 | 18 | 10525518 | NAPG | ENSG00000134265.8 | 1.246E-7 | 0 | -384 | gtex_brain_putamen_basal |
| RS512710 | 18 | 10525585 | NAPG | ENSG00000134265.8 | 7.234E-7 | 0 | -317 | gtex_brain_putamen_basal |
| RS2290279 | 18 | 10526187 | NAPG | ENSG00000134265.8 | 5.48e-7 | 0 | 285 | gtex_brain_putamen_basal |
| RS12962879 | 18 | 10526263 | NAPG | ENSG00000134265.8 | 7.502E-7 | 0 | 361 | gtex_brain_putamen_basal |
| RS7241196 | 18 | 10526413 | NAPG | ENSG00000134265.8 | 1.432E-7 | 0 | 511 | gtex_brain_putamen_basal |
| RS12968077 | 18 | 10527354 | NAPG | ENSG00000134265.8 | 3.565e-7 | 0 | 1452 | gtex_brain_putamen_basal |
| RS520218 | 18 | 10527637 | NAPG | ENSG00000134265.8 | 5.393E-9 | 0 | 1735年 | gtex_brain_putamen_basal |
| RS693679 | 18 | 10528039 | NAPG | ENSG00000134265.8 | 6.486e-7 | 0 | 2137 | gtex_brain_putamen_basal |
| RS485954 | 18 | 10528414 | NAPG | ENSG00000134265.8 | 6.486e-7 | 0 | 2512 | gtex_brain_putamen_basal |
| RS553754 | 18 | 10529822 | NAPG | ENSG00000134265.8 | 5.393E-9 | 0 | 3920 | gtex_brain_putamen_basal |
| RS509370 | 18 | 10530928 | NAPG | ENSG00000134265.8 | 5.393E-9 | 0 | 5026 | gtex_brain_putamen_basal |
| RS533675 | 18 | 10531606 | NAPG | ENSG00000134265.8 | 4.873E-7 | 0 | 5704 | gtex_brain_putamen_basal |
| RS538188 | 18 | 10532088 | NAPG | ENSG00000134265.8 | 8.612E-7 | 0 | 6186 | gtex_brain_putamen_basal |
| RS652521 | 18 | 10532897 | NAPG | ENSG00000134265.8 | 8.612E-7 | 0 | 6995 | gtex_brain_putamen_basal |
| RS641723 | 18 | 10532939 | NAPG | ENSG00000134265.8 | 4.873E-7 | 0 | 7037 | gtex_brain_putamen_basal |
| RS483995 | 18 | 10533302 | NAPG | ENSG00000134265.8 | 8.612E-7 | 0 | 7400 | gtex_brain_putamen_basal |
| RS397796119 | 18 | 10533797 | NAPG | ENSG00000134265.8 | 4.866E-7 | 0 | 7895 | gtex_brain_putamen_basal |
| RS495484 | 18 | 10535060 | NAPG | ENSG00000134265.8 | 5.867E-7 | 0 | 9158 | gtex_brain_putamen_basal |
| RS518605 | 18 | 10535119 | NAPG | ENSG00000134265.8 | 5.393E-9 | 0 | 9217 | gtex_brain_putamen_basal |
| RS522208 | 18 | 10535490 | NAPG | ENSG00000134265.8 | 4.873E-7 | 0 | 9588 | gtex_brain_putamen_basal |
| RS546966 | 18 | 10535913 | NAPG | ENSG00000134265.8 | 8.612E-7 | 0 | 10011 | gtex_brain_putamen_basal |
| RS550627 | 18 | 10536283 | NAPG | ENSG00000134265.8 | 8.612E-7 | 0 | 10381 | gtex_brain_putamen_basal |
| RS551586 | 18 | 10536628 | NAPG | ENSG00000134265.8 | 4.873E-7 | 0 | 10726 | gtex_brain_putamen_basal |
| RS580216 | 18 | 10536906 | NAPG | ENSG00000134265.8 | 8.612E-7 | 0 | 11004 | gtex_brain_putamen_basal |
| RS499169 | 18 | 10538129 | NAPG | ENSG00000134265.8 | 4.873E-7 | 0 | 12227 | gtex_brain_putamen_basal |
| RS526394 | 18 | 10538758 | NAPG | ENSG00000134265.8 | 1.516E-7 | 0 | 12856 | gtex_brain_putamen_basal |
| RS640832 | 18 | 10539739 | NAPG | ENSG00000134265.8 | 1.83E-6 | 0 | 13837 | gtex_brain_putamen_basal |
| RS510110 | 18 | 10540432 | NAPG | ENSG00000134265.8 | 4.576E-7 | 0 | 14530 | gtex_brain_putamen_basal |
| RS2308032 | 18 | 10540956 | NAPG | ENSG00000134265.8 | 4.428e-8 | 0 | 15054 | gtex_brain_putamen_basal |
| RS540701 | 18 | 10541510 | NAPG | ENSG00000134265.8 | 4.544e-7 | 0 | 15608 | gtex_brain_putamen_basal |
| RS611684 | 18 | 10541681 | NAPG | ENSG00000134265.8 | 3.37E-7 | 0 | 15779 | gtex_brain_putamen_basal |
| RS571229 | 18 | 10542459 | NAPG | ENSG00000134265.8 | 4.194E-7 | 0 | 16557 | gtex_brain_putamen_basal |
| RS571279 | 18 | 10542477 | NAPG | ENSG00000134265.8 | 4.544e-7 | 0 | 16575 | gtex_brain_putamen_basal |
| RS523000 | 18 | 10542501 | NAPG | ENSG00000134265.8 | 4.544e-7 | 0 | 16599 | gtex_brain_putamen_basal |
| RS552180 | 18 | 10543331 | NAPG | ENSG00000134265.8 | 4.544e-7 | 0 | 17429 | gtex_brain_putamen_basal |
| RS643757 | 18 | 10545688 | NAPG | ENSG00000134265.8 | 4.804e-9 | 0 | 19786年 | gtex_brain_putamen_basal |
| RS555446 | 18 | 10545918 | NAPG | ENSG00000134265.8 | 2.409E-10 | 0 | 20016 | gtex_brain_putamen_basal |
| RS632245 | 18 | 10545945 | NAPG | ENSG00000134265.8 | 2.931E-8 | 0 | 20043 | gtex_brain_putamen_basal |
| RS616139 | 18 | 10547257 | NAPG | ENSG00000134265.8 | 3.354e-7 | 0 | 21355 | gtex_brain_putamen_basal |
| RS614780 | 18 | 10547559 | NAPG | ENSG00000134265.8 | 5.658E-9 | 0 | 21657 | gtex_brain_putamen_basal |
| RS617040 | 18 | 10549362 | NAPG | ENSG00000134265.8 | 6.898E-9 | 0 | 23460 | gtex_brain_putamen_basal |
| RS547010 | 18 | 10549435 | NAPG | ENSG00000134265.8 | 3.583E-7 | 0 | 23533 | gtex_brain_putamen_basal |
| RS10207 | 18 | 10551782 | NAPG | ENSG00000134265.8 | 3.37E-7 | 0 | 25880 | gtex_brain_putamen_basal |
| RS665604 | 18 | 10553368 | NAPG | ENSG00000134265.8 | 3.37E-7 | 0 | 27466 | gtex_brain_putamen_basal |
| RS653624 | 18 | 10553789 | NAPG | ENSG00000134265.8 | 1.964E-9 | 0 | 27887 | gtex_brain_putamen_basal |
| RS9676242 | 18 | 10554459 | NAPG | ENSG00000134265.8 | 3.476E-8 | 0 | 28557 | gtex_brain_putamen_basal |
| RS484583 | 18 | 10555120 | NAPG | ENSG00000134265.8 | 5.393E-9 | 0 | 29218 | gtex_brain_putamen_basal |
| RS552076 | 18 | 10555135 | NAPG | ENSG00000134265.8 | 6.898E-9 | 0 | 29233 | gtex_brain_putamen_basal |
| RS510558 | 18 | 10555658 | NAPG | ENSG00000134265.8 | 3.37E-7 | 0 | 29756 | gtex_brain_putamen_basal |
| RS518271 | 18 | 10556480 | NAPG | ENSG00000134265.8 | 3.358e-7 | 0 | 30578 | gtex_brain_putamen_basal |
| RS516472 | 18 | 10556672 | NAPG | ENSG00000134265.8 | 3.356e-7 | 0 | 30770 | gtex_brain_putamen_basal |
| RS56658305 | 18 | 10556807 | NAPG | ENSG00000134265.8 | 3.154e-7 | 0 | 30905 | gtex_brain_putamen_basal |
| RS542448 | 18 | 10556836 | NAPG | ENSG00000134265.8 | 1.959E-7 | 0 | 30934 | gtex_brain_putamen_basal |
| RS575325 | 18 | 10564309 | NAPG | ENSG00000134265.8 | 1.5e-8 | 0 | 38407 | gtex_brain_putamen_basal |
第二节。转录组注释
一般基因表达（GTEX）
Devlopment期间的基因表达（BrainCloud）
脚注：
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。
时间变化的基因表达（brainspan）
脚注：
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。
大脑区域的顶级共表达基因
| 前10个积极共表达的基因 | ||
| 基因 | 皮尔逊的相关性 | 斯皮尔曼的相关性 |
| LDOC1L | 0.96 | 0.97 |
| ZNF398 | 0.95 | 0.96 |
| DTX4 | 0.95 | 0.96 |
| CAMSAP1 | 0.95 | 0.96 |
| KDM4B | 0.95 | 0.94 |
| SRGAP2 | 0.94 | 0.95 |
| SREBF2 | 0.94 | 0.96 |
| FAM123C | 0.94 | 0.96 |
| add2 | 0.94 | 0.96 |
| MTMR4 | 0.94 | 0.95 |
| 前10个负共表达基因 | ||
| 基因 | 皮尔逊的相关性 | 斯皮尔曼的相关性 |
| serpinb6 | -0.73 | -0.79 |
| S100B | -0.73 | -0.87 |
| hepn1 | -0.72 | -0.79 |
| AF347015.31 | -0.72 | -0.89 |
| AIFM3 | -0.72 | -0.78 |
| MT-CO2 | -0.71 | -0.90 |
| FXYD1 | -0.71 | -0.88 |
| HSD17B14 | -0.71 | -0.80 |
| TSC22D4 | -0.71 | -0.79 |
| C5orf53 | -0.71 | -0.77 |
V.途径注释
| 路径名 | 路径大小 | ＃szgr 2.0基因 | 信息 |
|---|---|---|---|
| Provenzani转移DN | 136 | 94 | 该途径中的所有SZGR 2.0基因 |
| 胡血管生成 | 21 | 16 | 该途径中的所有SZGR 2.0基因 |
| Heidenblad Amplicon 8Q24 DN | 46 | 28 | 该途径中的所有SZGR 2.0基因 |
| 按拷贝数量的丁肺癌表达 | 100 | 62 | 该途径中的所有SZGR 2.0基因 |
| 与FLT3突变DN的大风APL | 17 | 10 | 该途径中的所有SZGR 2.0基因 |
| 伊万诺娃造血晚期祖先 | 544 | 307 | 该途径中的所有SZGR 2.0基因 |
| lu衰老的脑dn | 153 | 120 | 该途径中的所有SZGR 2.0基因 |
| 贝尔德糖尿病性肾病DN | 434 | 302 | 该途径中的所有SZGR 2.0基因 |
| 对Salirasib的反应 | 245 | 159 | 该途径中的所有SZGR 2.0基因 |
| Pilon KLF1靶向 | 504 | 321 | 该途径中的所有SZGR 2.0基因 |
| Fortschegger PHF8靶向DN | 784 | 464 | 该途径中的所有SZGR 2.0基因 |
| boudoukha由IGF2BP2绑定 | 111 | 59 | 该途径中的所有SZGR 2.0基因 |