Gene Page:EFCAB11

Summary?
GeneID 90141
Symbol EFCAB11
Synonyms C14orf143
Description EF-hand calcium binding domain 11
Reference HGNC:HGNC:20357|Ensembl:ENSG00000140025|HPRD:16609|Vega:OTTHUMG00000148671
Gene type protein-coding
Map location 14q32.11
Pascal p-value 0.584
Fetal beta -0.604
eGene Putamen basal ganglia
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search 系统搜索PubMed co-occ基因urring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs7370564 0 EFCAB11 90141 0.07 trans
rs1469347 chr2 126401820 EFCAB11 90141 0.2 trans
rs2070396 chr21 30878751 EFCAB11 90141 0.2 trans
rs7157108 14 90389239 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 31882 gtex_brain_putamen_basal
rs17126460 14 90389515 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 31606 gtex_brain_putamen_basal
rs4456438 14 90389665 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 31456 gtex_brain_putamen_basal
rs2281749 14 90389969 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 31152 gtex_brain_putamen_basal
rs2281750 14 90389998 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 31123 gtex_brain_putamen_basal
rs2281751 14 90390114 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 31007 gtex_brain_putamen_basal
rs2281752 14 90390457 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 30664 gtex_brain_putamen_basal
rs2281753 14 90390566 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 30555 gtex_brain_putamen_basal
rs2281754 14 90390631 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 30490 gtex_brain_putamen_basal
rs12100727 14 90390948 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 30173 gtex_brain_putamen_basal
rs12101251 14 90390968 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 30153 gtex_brain_putamen_basal
rs11159940 14 90391072 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 30049 gtex_brain_putamen_basal
rs55921830 14 90391595 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 29526 gtex_brain_putamen_basal
rs56034277 14 90391886 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 29235 gtex_brain_putamen_basal
rs12100947 14 90392259 EFCAB11 ENSG00000140025.11 1.547E-6 0.02 28862 gtex_brain_putamen_basal
rs12100540 14 90392294 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 28827 gtex_brain_putamen_basal
rs60345558 14 90392770 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 28351 gtex_brain_putamen_basal
rs57584574 14 90393192 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 27929 gtex_brain_putamen_basal
rs8013178 14 90393855 EFCAB11 ENSG00000140025.11 1.515E-6 0.02 27266 gtex_brain_putamen_basal
rs59664157 14 90393905 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 27216 gtex_brain_putamen_basal
rs72697352 14 90393910 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 27211 gtex_brain_putamen_basal
rs2401857 14 90394390 EFCAB11 ENSG00000140025.11 1.528E-6 0.02 26731 gtex_brain_putamen_basal
rs2401858 14 90394401 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 26720 gtex_brain_putamen_basal
rs2401859 14 90394419 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 26702 gtex_brain_putamen_basal
rs4293304 14 90394514 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 26607 gtex_brain_putamen_basal
rs72697355 14 90394784 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 26337 gtex_brain_putamen_basal
rs113614821 14 90395225 EFCAB11 ENSG00000140025.11 7.611E-7 0.02 25896 gtex_brain_putamen_basal
rs72697358 14 90395594 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 25527 gtex_brain_putamen_basal
rs11845113 14 90396226 EFCAB11 ENSG00000140025.11 1.184E-6 0.02 24895 gtex_brain_putamen_basal
rs11845327 14 90396591 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 24530 gtex_brain_putamen_basal
rs56105603 14 90396815 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 24306 gtex_brain_putamen_basal
rs55633141 14 90396823 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 24298 gtex_brain_putamen_basal
rs12050176 14 90397158 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 23963 gtex_brain_putamen_basal
rs12050388 14 90397347 EFCAB11 ENSG00000140025.11 1.476E-6 0.02 23774 gtex_brain_putamen_basal
rs12050178 14 90397404 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 23717 gtex_brain_putamen_basal
rs12050183 14 90397445 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 23676 gtex_brain_putamen_basal
rs12050179 14 90397481 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 23640 gtex_brain_putamen_basal
rs59272086 14 90397590 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 23531 gtex_brain_putamen_basal
rs57465932 14 90397718 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 23403 gtex_brain_putamen_basal
rs72459741 14 90398364 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 22757 gtex_brain_putamen_basal
rs8778 14 90398907 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 22214 gtex_brain_putamen_basal
rs3752966 14 90399058 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 22063 gtex_brain_putamen_basal
rs72697362 14 90399169 EFCAB11 ENSG00000140025.11 1.499E-6 0.02 21952 gtex_brain_putamen_basal
rs12232164 14 90417508 EFCAB11 ENSG00000140025.11 1.337E-6 0.02 3613 gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
GINESTIER BREAST CANCER 20Q13 AMPLIFICATION UP 119 66 All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER BASAL VS LULMINAL 330 215 All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 1652 1023 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN 1024 594 All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS UP 344 180 All SZGR 2.0 genes in this pathway
GEORGES TARGETS OF MIR192 AND MIR215 893 528 All SZGR 2.0 genes in this pathway
XU GH1 AUTOCRINE TARGETS UP 268 157 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953 554 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783 442 All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728 415 All SZGR 2.0 genes in this pathway
TAVAZOIE METASTASIS 108 68 All SZGR 2.0 genes in this pathway
PANGAS TUMOR SUPPRESSION BY SMAD1 AND SMAD5 DN 157 106 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784 464 All SZGR 2.0 genes in this pathway