Gene Page:IL1RL1

Summary?
GeneID 9173
Symbol IL1RL1
Synonyms DER4|FIT-1|IL33R|ST2|ST2L|ST2V|T1
Description interleukin 1 receptor like 1
Reference MIM:601203|HGNC:HGNC:5998|Ensembl:ENSG00000115602|HPRD: 03123|Vega:OTTHUMG00000130782
Gene type protein-coding
Map location 2q12
Fetal beta -0.127
eGene Anterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Meta

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
GSMA_I Genome scan meta-analysis Psr: 0.0004

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs1115282 2 102890970 IL1RL1 ENSG00000115602.12 1.482E-6 0 -38399 gtex_brain_ba24
rs11123917 2 102891649 IL1RL1 ENSG00000115602.12 1.466E-6 0 -37720 gtex_brain_ba24
rs11683213 2 102904244 IL1RL1 ENSG00000115602.12 9.108E-7 0 -25125 gtex_brain_ba24
rs1420091 2 102917234 IL1RL1 ENSG00000115602.12 2.669E-9 0 -12135 gtex_brain_ba24
rs4399750 2 102917788 IL1RL1 ENSG00000115602.12 2.789E-9 0 -11581 gtex_brain_ba24
rs2110660 2 102918601 IL1RL1 ENSG00000115602.12 1.04E-9 0 -10768 gtex_brain_ba24
rs35727090 2 102918925 IL1RL1 ENSG00000115602.12 3.071E-9 0 -10444 gtex_brain_ba24
rs200094563 2 102918931 IL1RL1 ENSG00000115602.12 1.635E-8 0 -10438 gtex_brain_ba24
rs1420090 2 102919305 IL1RL1 ENSG00000115602.12 2.963E-9 0 -10064 gtex_brain_ba24
rs7565653 2 102919426 IL1RL1 ENSG00000115602.12 2.789E-9 0 -9943 gtex_brain_ba24
rs7568913 2 102920037 IL1RL1 ENSG00000115602.12 9.885E-10 0 -9332 gtex_brain_ba24
rs10179654 2 102921783 IL1RL1 ENSG00000115602.12 9.388E-10 0 -7586 gtex_brain_ba24
rs4090473 2 102922987 IL1RL1 ENSG00000115602.12 2.789E-9 0 -6382 gtex_brain_ba24
rs67627960 2 102923677 IL1RL1 ENSG00000115602.12 2.224E-8 0 -5692 gtex_brain_ba24
rs11683957 2 102923821 IL1RL1 ENSG00000115602.12 1.17E-9 0 -5548 gtex_brain_ba24
rs12476925 2 102924549 IL1RL1 ENSG00000115602.12 7.474E-10 0 -4820 gtex_brain_ba24
rs12476968 2 102924662 IL1RL1 ENSG00000115602.12 7.545E-10 0 -4707 gtex_brain_ba24
rs6721346 2 102926320 IL1RL1 ENSG00000115602.12 7.474E-10 0 -3049 gtex_brain_ba24
rs10178436 2 102926511 IL1RL1 ENSG00000115602.12 7.474E-10 0 -2858 gtex_brain_ba24
rs11679191 2 102926800 IL1RL1 ENSG00000115602.12 7.508E-10 0 -2569 gtex_brain_ba24
rs11685424 2 102926981 IL1RL1 ENSG00000115602.12 7.474E-10 0 -2388 gtex_brain_ba24
rs11685480 2 102927086 IL1RL1 ENSG00000115602.12 2.789E-9 0 -2283 gtex_brain_ba24
rs6733174 2 102929012 IL1RL1 ENSG00000115602.12 7.474E-10 0 -357 gtex_brain_ba24
rs6543118 2 102929469 IL1RL1 ENSG00000115602.12 7.474E-10 0 100 gtex_brain_ba24
rs1558622 2 102930147 IL1RL1 ENSG00000115602.12 2.789E-9 0 778 gtex_brain_ba24
rs1558621 2 102930307 IL1RL1 ENSG00000115602.12 7.465E-10 0 938 gtex_brain_ba24
rs10189202 2 102930380 IL1RL1 ENSG00000115602.12 2.789E-9 0 1011 gtex_brain_ba24
rs34646353 2 102930605 IL1RL1 ENSG00000115602.12 3.322E-8 0 1236 gtex_brain_ba24
rs10191914 2 102930657 IL1RL1 ENSG00000115602.12 2.789E-9 0 1288 gtex_brain_ba24
rs10189711 2 102930881 IL1RL1 ENSG00000115602.12 7.474E-10 0 1512 gtex_brain_ba24
rs12712135 2 102930948 IL1RL1 ENSG00000115602.12 7.474E-10 0 1579 gtex_brain_ba24
rs1558620 2 102931395 IL1RL1 ENSG00000115602.12 2.789E-9 0 2026 gtex_brain_ba24
rs1558619 2 102931550 IL1RL1 ENSG00000115602.12 7.474E-10 0 2181 gtex_brain_ba24
rs12996505 2 102931802 IL1RL1 ENSG00000115602.12 2.789E-9 0 2433 gtex_brain_ba24
rs13020793 2 102931926 IL1RL1 ENSG00000115602.12 2.789E-9 0 2557 gtex_brain_ba24
rs10183388 2 102932247 IL1RL1 ENSG00000115602.12 2.789E-9 0 2878 gtex_brain_ba24
rs953934 2 102932293 IL1RL1 ENSG00000115602.12 6.343E-9 0 2924 gtex_brain_ba24
rs1968171 2 102933552 IL1RL1 ENSG00000115602.12 2.789E-9 0 4183 gtex_brain_ba24
rs4613307 2 102933758 IL1RL1 ENSG00000115602.12 2.789E-9 0 4389 gtex_brain_ba24
rs1968170 2 102933802 IL1RL1 ENSG00000115602.12 2.789E-9 0 4433 gtex_brain_ba24
rs11123918 2 102935237 IL1RL1 ENSG00000115602.12 2.986E-9 0 5868 gtex_brain_ba24
rs10182639 2 102935805 IL1RL1 ENSG00000115602.12 2.789E-9 0 6436 gtex_brain_ba24
rs11690443 2 102936131 IL1RL1 ENSG00000115602.12 2.789E-9 0 6762 gtex_brain_ba24
rs12712136 2 102936366 IL1RL1 ENSG00000115602.12 1.187E-8 0 6997 gtex_brain_ba24
rs974389 2 102936981 IL1RL1 ENSG00000115602.12 6.343E-9 0 7612 gtex_brain_ba24
rs4142132 2 102937482 IL1RL1 ENSG00000115602.12 2.789E-9 0 8113 gtex_brain_ba24
rs971764 2 102938335 IL1RL1 ENSG00000115602.12 6.343E-9 0 8966 gtex_brain_ba24
rs1420088 2 102939434 IL1RL1 ENSG00000115602.12 2.789E-9 0 10065 gtex_brain_ba24
rs11123920 2 102939833 IL1RL1 ENSG00000115602.12 2.789E-9 0 10464 gtex_brain_ba24
rs6706844 2 102940412 IL1RL1 ENSG00000115602.12 6.347E-9 0 11043 gtex_brain_ba24
rs11674832 2 102940999 IL1RL1 ENSG00000115602.12 2.456E-6 0 11630 gtex_brain_ba24
rs11675988 2 102941019 IL1RL1 ENSG00000115602.12 1.841E-6 0 11650 gtex_brain_ba24
rs11679900 2 102941074 IL1RL1 ENSG00000115602.12 2.789E-9 0 11705 gtex_brain_ba24
rs11676075 2 102941215 IL1RL1 ENSG00000115602.12 2.789E-9 0 11846 gtex_brain_ba24
rs11676124 2 102941338 IL1RL1 ENSG00000115602.12 1.834E-6 0 11969 gtex_brain_ba24
rs11123921 2 102941561 IL1RL1 ENSG00000115602.12 2.788E-9 0 12192 gtex_brain_ba24
rs76520363 2 102945241 IL1RL1 ENSG00000115602.12 2.789E-9 0 15872 gtex_brain_ba24
rs76278109 2 102945378 IL1RL1 ENSG00000115602.12 1.911E-7 0 16009 gtex_brain_ba24
rs76886731 2 102945416 IL1RL1 ENSG00000115602.12 8.213E-8 0 16047 gtex_brain_ba24
rs150341880 2 102945755 IL1RL1 ENSG00000115602.12 3.693E-9 0 16386 gtex_brain_ba24
rs138087973 2 102946082 IL1RL1 ENSG00000115602.12 1.489E-8 0 16713 gtex_brain_ba24
rs76498201 2 102946111 IL1RL1 ENSG00000115602.12 2.012E-8 0 16742 gtex_brain_ba24
rs12996772 2 102947201 IL1RL1 ENSG00000115602.12 2.789E-9 0 17832 gtex_brain_ba24
rs1420102 2 102948819 IL1RL1 ENSG00000115602.12 6.343E-9 0 19450 gtex_brain_ba24
rs12466380 2 102948939 IL1RL1 ENSG00000115602.12 2.789E-9 0 19570 gtex_brain_ba24
rs12712140 2 102951062 IL1RL1 ENSG00000115602.12 2.919E-9 0 21693 gtex_brain_ba24
rs1997467 2 102951073 IL1RL1 ENSG00000115602.12 2.789E-9 0 21704 gtex_brain_ba24
rs1997466 2 102951467 IL1RL1 ENSG00000115602.12 2.788E-9 0 22098 gtex_brain_ba24
rs1362350 2 102951798 IL1RL1 ENSG00000115602.12 2.797E-9 0 22429 gtex_brain_ba24
rs67058052 2 102951850 IL1RL1 ENSG00000115602.12 3.359E-9 0 22481 gtex_brain_ba24
rs397969654 2 102951851 IL1RL1 ENSG00000115602.12 3.301E-9 0 22482 gtex_brain_ba24
rs1362349 2 102951972 IL1RL1 ENSG00000115602.12 3.255E-9 0 22603 gtex_brain_ba24
rs12712141 2 102953067 IL1RL1 ENSG00000115602.12 1.112E-8 0 23698 gtex_brain_ba24
rs59247511 2 102954190 IL1RL1 ENSG00000115602.12 3.116E-9 0 24821 gtex_brain_ba24
rs55664618 2 103016216 IL1RL1 ENSG00000115602.12 1.563E-7 0 86847 gtex_brain_ba24
rs11465727 2 103064503 IL1RL1 ENSG00000115602.12 5.32E-7 0 135134 gtex_brain_ba24
rs11465730 2 103066858 IL1RL1 ENSG00000115602.12 5.994E-7 0 137489 gtex_brain_ba24
rs11678721 2 103073238 IL1RL1 ENSG00000115602.12 8.884E-7 0 143869 gtex_brain_ba24
rs11677555 2 103073293 IL1RL1 ENSG00000115602.12 5.994E-7 0 143924 gtex_brain_ba24
rs6728475 2 103073950 IL1RL1 ENSG00000115602.12 5.982E-7 0 144581 gtex_brain_ba24
rs12712150 2 103074813 IL1RL1 ENSG00000115602.12 5.817E-7 0 145444 gtex_brain_ba24
rs6705498 2 103076670 IL1RL1 ENSG00000115602.12 5.994E-7 0 147301 gtex_brain_ba24
rs6719196 2 103076888 IL1RL1 ENSG00000115602.12 5.994E-7 0 147519 gtex_brain_ba24
rs11676236 2 103081695 IL1RL1 ENSG00000115602.12 5.994E-7 0 152326 gtex_brain_ba24
rs11687013 2 103081721 IL1RL1 ENSG00000115602.12 5.994E-7 0 152352 gtex_brain_ba24
rs4140786 2 103088176 IL1RL1 ENSG00000115602.12 5.994E-7 0 158807 gtex_brain_ba24
rs1115282 2 102890970 IL1RL1 ENSG00000115602.12 5.141E-6 0 -38399 gtex_brain_putamen_basal
rs11123917 2 102891649 IL1RL1 ENSG00000115602.12 4.807E-6 0 -37720 gtex_brain_putamen_basal
rs11683213 2 102904244 IL1RL1 ENSG00000115602.12 2.673E-6 0 -25125 gtex_brain_putamen_basal
rs1420091 2 102917234 IL1RL1 ENSG00000115602.12 3.697E-9 0 -12135 gtex_brain_putamen_basal
rs4399750 2 102917788 IL1RL1 ENSG00000115602.12 3.739E-9 0 -11581 gtex_brain_putamen_basal
rs2110660 2 102918601 IL1RL1 ENSG00000115602.12 6.22E-11 0 -10768 gtex_brain_putamen_basal
rs35727090 2 102918925 IL1RL1 ENSG00000115602.12 1.591E-8 0 -10444 gtex_brain_putamen_basal
rs200094563 2 102918931 IL1RL1 ENSG00000115602.12 2.029 e-8 0 -10438 gtex_brain_putamen_basal
rs1420090 2 102919305 IL1RL1 ENSG00000115602.12 9.865E-9 0 -10064 gtex_brain_putamen_basal
rs7565653 2 102919426 IL1RL1 ENSG00000115602.12 3.734E-9 0 -9943 gtex_brain_putamen_basal
rs7568913 2 102920037 IL1RL1 ENSG00000115602.12 5.897E-11 0 -9332 gtex_brain_putamen_basal
rs10179654 2 102921783 IL1RL1 ENSG00000115602.12 5.647E-11 0 -7586 gtex_brain_putamen_basal
rs4090473 2 102922987 IL1RL1 ENSG00000115602.12 3.723E-9 0 -6382 gtex_brain_putamen_basal
rs67627960 2 102923677 IL1RL1 ENSG00000115602.12 1.119E-8 0 -5692 gtex_brain_putamen_basal
rs12476925 2 102924549 IL1RL1 ENSG00000115602.12 5.277E-11 0 -4820 gtex_brain_putamen_basal
rs12476968 2 102924662 IL1RL1 ENSG00000115602.12 5.277E-11 0 -4707 gtex_brain_putamen_basal
rs6721346 2 102926320 IL1RL1 ENSG00000115602.12 5.277E-11 0 -3049 gtex_brain_putamen_basal
rs10178436 2 102926511 IL1RL1 ENSG00000115602.12 5.277E-11 0 -2858 gtex_brain_putamen_basal
rs11679191 2 102926800 IL1RL1 ENSG00000115602.12 2.025E-11 0 -2569 gtex_brain_putamen_basal
rs11685424 2 102926981 IL1RL1 ENSG00000115602.12 5.277E-11 0 -2388 gtex_brain_putamen_basal
rs11685480 2 102927086 IL1RL1 ENSG00000115602.12 3.739E-9 0 -2283 gtex_brain_putamen_basal
rs6733174 2 102929012 IL1RL1 ENSG00000115602.12 5.246E-11 0 -357 gtex_brain_putamen_basal
rs6543118 2 102929469 IL1RL1 ENSG00000115602.12 5.264E-11 0 100 gtex_brain_putamen_basal
rs1558622 2 102930147 IL1RL1 ENSG00000115602.12 3.734E-9 0 778 gtex_brain_putamen_basal
rs1558621 2 102930307 IL1RL1 ENSG00000115602.12 5.272E-11 0 938 gtex_brain_putamen_basal
rs10189202 2 102930380 IL1RL1 ENSG00000115602.12 3.736E-9 0 1011 gtex_brain_putamen_basal
rs34646353 2 102930605 IL1RL1 ENSG00000115602.12 5.274E-9 0 1236 gtex_brain_putamen_basal
rs10191914 2 102930657 IL1RL1 ENSG00000115602.12 3.739E-9 0 1288 gtex_brain_putamen_basal
rs10189711 2 102930881 IL1RL1 ENSG00000115602.12 5.277E-11 0 1512 gtex_brain_putamen_basal
rs12712135 2 102930948 IL1RL1 ENSG00000115602.12 5.277E-11 0 1579 gtex_brain_putamen_basal
rs1558620 2 102931395 IL1RL1 ENSG00000115602.12 3.739E-9 0 2026 gtex_brain_putamen_basal
rs1558619 2 102931550 IL1RL1 ENSG00000115602.12 8.541E-11 0 2181 gtex_brain_putamen_basal
rs12996505 2 102931802 IL1RL1 ENSG00000115602.12 3.976E-9 0 2433 gtex_brain_putamen_basal
rs13020793 2 102931926 IL1RL1 ENSG00000115602.12 3.739E-9 0 2557 gtex_brain_putamen_basal
rs10183388 2 102932247 IL1RL1 ENSG00000115602.12 3.739E-9 0 2878 gtex_brain_putamen_basal
rs953934 2 102932293 IL1RL1 ENSG00000115602.12 2.409E-9 0 2924 gtex_brain_putamen_basal
rs1968171 2 102933552 IL1RL1 ENSG00000115602.12 4.305E-9 0 4183 gtex_brain_putamen_basal
rs4613307 2 102933758 IL1RL1 ENSG00000115602.12 1.903E-9 0 4389 gtex_brain_putamen_basal
rs1968170 2 102933802 IL1RL1 ENSG00000115602.12 4.466E-9 0 4433 gtex_brain_putamen_basal
rs11123918 2 102935237 IL1RL1 ENSG00000115602.12 8.056E-9 0 5868 gtex_brain_putamen_basal
rs10182639 2 102935805 IL1RL1 ENSG00000115602.12 9.348E-9 0 6436 gtex_brain_putamen_basal
rs11690443 2 102936131 IL1RL1 ENSG00000115602.12 1.004E-8 0 6762 gtex_brain_putamen_basal
rs12712136 2 102936366 IL1RL1 ENSG00000115602.12 1.02E-8 0 6997 gtex_brain_putamen_basal
rs974389 2 102936981 IL1RL1 ENSG00000115602.12 6.68E-9 0 7612 gtex_brain_putamen_basal
rs4142132 2 102937482 IL1RL1 ENSG00000115602.12 1.289E-8 0 8113 gtex_brain_putamen_basal
rs971764 2 102938335 IL1RL1 ENSG00000115602.12 8.101E-9 0 8966 gtex_brain_putamen_basal
rs1420088 2 102939434 IL1RL1 ENSG00000115602.12 1.557E-8 0 10065 gtex_brain_putamen_basal
rs11123920 2 102939833 IL1RL1 ENSG00000115602.12 1.557E-8 0 10464 gtex_brain_putamen_basal
rs6706844 2 102940412 IL1RL1 ENSG00000115602.12 8.767E-9 0 11043 gtex_brain_putamen_basal
rs11674832 2 102940999 IL1RL1 ENSG00000115602.12 1.414E-6 0 11630 gtex_brain_putamen_basal
rs11679900 2 102941074 IL1RL1 ENSG00000115602.12 1.68E-8 0 11705 gtex_brain_putamen_basal
rs11676075 2 102941215 IL1RL1 ENSG00000115602.12 1.557E-8 0 11846 gtex_brain_putamen_basal
rs11123921 2 102941561 IL1RL1 ENSG00000115602.12 1.557E-8 0 12192 gtex_brain_putamen_basal
rs76520363 2 102945241 IL1RL1 ENSG00000115602.12 1.557E-8 0 15872 gtex_brain_putamen_basal
rs76278109 2 102945378 IL1RL1 ENSG00000115602.12 9.603E-7 0 16009 gtex_brain_putamen_basal
rs76886731 2 102945416 IL1RL1 ENSG00000115602.12 1.01E-7 0 16047 gtex_brain_putamen_basal
rs150341880 2 102945755 IL1RL1 ENSG00000115602.12 1.238E-8 0 16386 gtex_brain_putamen_basal
rs138087973 2 102946082 IL1RL1 ENSG00000115602.12 1.876E-8 0 16713 gtex_brain_putamen_basal
rs76498201 2 102946111 IL1RL1 ENSG00000115602.12 1.106E-8 0 16742 gtex_brain_putamen_basal
rs12996772 2 102947201 IL1RL1 ENSG00000115602.12 1.557E-8 0 17832 gtex_brain_putamen_basal
rs1420102 2 102948819 IL1RL1 ENSG00000115602.12 8.979E-9 0 19450 gtex_brain_putamen_basal
rs12466380 2 102948939 IL1RL1 ENSG00000115602.12 1.557E-8 0 19570 gtex_brain_putamen_basal
rs12712140 2 102951062 IL1RL1 ENSG00000115602.12 1.641E-8 0 21693 gtex_brain_putamen_basal
rs1997467 2 102951073 IL1RL1 ENSG00000115602.12 1.557E-8 0 21704 gtex_brain_putamen_basal
rs1997466 2 102951467 IL1RL1 ENSG00000115602.12 1.556E-8 0 22098 gtex_brain_putamen_basal
rs1362350 2 102951798 IL1RL1 ENSG00000115602.12 1.555E-8 0 22429 gtex_brain_putamen_basal
rs67058052 2 102951850 IL1RL1 ENSG00000115602.12 2.031E-8 0 22481 gtex_brain_putamen_basal
rs397969654 2 102951851 IL1RL1 ENSG00000115602.12 1.238E-8 0 22482 gtex_brain_putamen_basal
rs1362349 2 102951972 IL1RL1 ENSG00000115602.12 1.63E-8 0 22603 gtex_brain_putamen_basal
rs12712141 2 102953067 IL1RL1 ENSG00000115602.12 1.557E-8 0 23698 gtex_brain_putamen_basal
rs59247511 2 102954190 IL1RL1 ENSG00000115602.12 1.565E-8 0 24821 gtex_brain_putamen_basal
rs55664618 2 103016216 IL1RL1 ENSG00000115602.12 3.774E-7 0 86847 gtex_brain_putamen_basal
rs11465727 2 103064503 IL1RL1 ENSG00000115602.12 4.008E-7 0 135134 gtex_brain_putamen_basal
rs35566453 2 103064508 IL1RL1 ENSG00000115602.12 3.31E-6 0 135139 gtex_brain_putamen_basal
rs397873851 2 103064511 IL1RL1 ENSG00000115602.12 3.335E-6 0 135142 gtex_brain_putamen_basal
rs11465730 2 103066858 IL1RL1 ENSG00000115602.12 7.279 e - 0 137489 gtex_brain_putamen_basal
rs11678721 2 103073238 IL1RL1 ENSG00000115602.12 3.15E-6 0 143869 gtex_brain_putamen_basal
rs11677555 2 103073293 IL1RL1 ENSG00000115602.12 7.279 e - 0 143924 gtex_brain_putamen_basal
rs6728475 2 103073950 IL1RL1 ENSG00000115602.12 7.279 e - 0 144581 gtex_brain_putamen_basal
rs12712150 2 103074813 IL1RL1 ENSG00000115602.12 6.749E-7 0 145444 gtex_brain_putamen_basal
rs6705385 2 103076569 IL1RL1 ENSG00000115602.12 2.243E-6 0 147200 gtex_brain_putamen_basal
rs6705498 2 103076670 IL1RL1 ENSG00000115602.12 7.279 e - 0 147301 gtex_brain_putamen_basal
rs6719196 2 103076888 IL1RL1 ENSG00000115602.12 7.279 e - 0 147519 gtex_brain_putamen_basal
rs11676236 2 103081695 IL1RL1 ENSG00000115602.12 7.279 e - 0 152326 gtex_brain_putamen_basal
rs11687013 2 103081721 IL1RL1 ENSG00000115602.12 7.279 e - 0 152352 gtex_brain_putamen_basal
rs12463588 2 103085257 IL1RL1 ENSG00000115602.12 2.243E-6 0 155888 gtex_brain_putamen_basal
rs2310302 2 103086049 IL1RL1 ENSG00000115602.12 2.243E-6 0 156680 gtex_brain_putamen_basal
rs12469887 2 103086758 IL1RL1 ENSG00000115602.12 2.243E-6 0 157389 gtex_brain_putamen_basal
rs10195075 2 103087652 IL1RL1 ENSG00000115602.12 1.891E-6 0 158283 gtex_brain_putamen_basal
rs1403553 2 103087662 IL1RL1 ENSG00000115602.12 1.891E-6 0 158293 gtex_brain_putamen_basal
rs4140786 2 103088176 IL1RL1 ENSG00000115602.12 7.279 e - 0 158807 gtex_brain_putamen_basal
rs10201184 2 103089078 IL1RL1 ENSG00000115602.12 2.243E-6 0 159709 gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
ANKRD44 0.91 0.92
RRP1B 0.91 0.92
SEC24A 0.91 0.95
PRRC1 0.90 0.92
SPAST 0.90 0.94
IGSF3 0.90 0.89
URB2 0.90 0.92
EPM2AIP1 0.90 0.93
MFHAS1 0.90 0.90
ZXDA 0.90 0.92
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
FXYD1 -0.66 -0.84
AF347015.31 -0.64 -0.81
MT-CO2 -0.64 -0.82
IFI27 -0.63 -0.80
C5orf53 -0.63 -0.71
AF347015.33 -0.63 -0.79
CXCL14 -0.62 -0.82
AF347015.27 -0.62 -0.78
HIGD1B -0.62 -0.80
HLA-F -0.61 -0.70

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0005057 receptor signaling protein activity TAS 1482686
GO:0004888 transmembrane receptor activity IEA -
GO:0005515 protein binding 新闻学会 16286016
GO:0004908 interleukin-1 receptor activity IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0007165 signal transduction TAS 1482686
GO:0045087 innate immune response IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005813 centrosome IDA 18029348
GO:0005576 extracellular region IEA -
GO:0005737 cytoplasm IDA 18029348
GO:0016021 integral to membrane IEA -
GO:0005925 focal adhesion IDA 18029348
GO:0005886 plasma membrane IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN 634 384 All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC UP 185 126 All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN 51 35 All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS UP 126 72 All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION CDC25 UP 120 73 All SZGR 2.0 genes in this pathway
MARKEY RB1 CHRONIC LOF UP 115 78 All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA UP 536 340 All SZGR 2.0 genes in this pathway
HERNANDEZ ABERRANT MITOSIS BY DOCETACEL 2NM DN 25 18 All SZGR 2.0 genes in this pathway
HERNANDEZ MITOTIC ARREST BY DOCETAXEL 2 UP 64 45 All SZGR 2.0 genes in this pathway
WATTEL AUTONOMOUS THYROID ADENOMA DN 55 29 All SZGR 2.0 genes in this pathway
SASAI RESISTANCE TO NEOPLASTIC TRANSFROMATION 50 31 All SZGR 2.0 genes in this pathway
LIANG HEMATOPOIESIS STEM CELL NUMBER LARGE VS TINY DN 45 24 All SZGR 2.0 genes in this pathway
RICKMAN HEAD AND NECK CANCER C 113 47 All SZGR 2.0 genes in this pathway
OKUMURA INFLAMMATORY RESPONSE LPS 183 115 All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882 572 All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL FLI1 9 8 All SZGR 2.0 genes in this pathway
NEMETH INFLAMMATORY RESPONSE LPS UP 88 64 All SZGR 2.0 genes in this pathway
AFFAR YY1 TARGETS DN 234 137 All SZGR 2.0 genes in this pathway
KUMAR TARGETS OF MLL AF9 FUSION 405 264 All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR 544 307 All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE UP 249 170 All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV NHEK UP 244 151 All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 2 72 52 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 18HR UP 178 111 All SZGR 2.0 genes in this pathway
HAN JNK SINGALING UP 35 21 All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS PEAK AT 8HR 39 31 All SZGR 2.0 genes in this pathway
MONNIER POSTRADIATION TUMOR ESCAPE UP 393 244 All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P4 100 62 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS DN 543 317 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS UP 602 364 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS UP 601 369 All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER WITH H3K27ME3 UP 295 149 All SZGR 2.0 genes in this pathway
ZHENG IL22 SIGNALING DN 42 26 All SZGR 2.0 genes in this pathway
MATTHEWS AP1 TARGETS 17 12 All SZGR 2.0 genes in this pathway
ALONSO METASTASIS UP 198 128 All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C D DN 252 155 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
DAZARD UV RESPONSE CLUSTER G24 28 19 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP C 92 60 All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682 433 All SZGR 2.0 genes in this pathway
TORCHIA TARGETS OF EWSR1 FLI1 FUSION UP 271 165 All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824 528 All SZGR 2.0 genes in this pathway
KATSANOU ELAVL1 TARGETS DN 148 88 All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 10HR UP 199 143 All SZGR 2.0 genes in this pathway
WANG MLL TARGETS 289 188 All SZGR 2.0 genes in this pathway
DURAND STROMA S UP 297 194 All SZGR 2.0 genes in this pathway