Gene Page:EPSTI1

Summary?
GeneID 94240
Symbol EPSTI1
Synonyms BRESI1
Description epithelial stromal interaction 1 (breast)
Reference MIM:607441|HGNC:HGNC:16465|Ensembl:ENSG00000133106|HPRD:06309|Vega:OTTHUMG00000016814
Gene type protein-coding
Map location 13q13.3
Pascal p-value 0.905
Sherlock p-value 0.425
Fetal beta 0.06
DMG 1 (# studies)
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg25261228 13 43566114 EPSTI1 1.118E-4 -0.213 0.029 DMG:Wockner_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs3766034 chr1 169087664 EPSTI1 94240 0.05 trans
rs12748624 chr1 169189770 EPSTI1 94240 0.17 trans
rs10495652 chr2 17139288 EPSTI1 94240 0.05 trans
rs6531271 chr2 17139932 EPSTI1 94240 0.05 trans
rs12620194 chr2 17148003 EPSTI1 94240 0.05 trans
rs9397692 chr6 154487314 EPSTI1 94240 0.17 trans
rs6477661 chr9 111399284 EPSTI1 94240 0.14 trans
rs10816692 chr9 111403558 EPSTI1 94240 0.09 trans
rs894376 chr10 99674122 EPSTI1 94240 0.17 trans
rs2592926 chr11 127251272 EPSTI1 94240 0.1 trans
rs12577873 chr11 127261987 EPSTI1 94240 0.1 trans
rs10507881 chr13 78760860 EPSTI1 94240 0.05 trans
rs17000632 chr20 53676802 EPSTI1 94240 0.14 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463 290 All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS UP 306 188 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP 182 110 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D UP 157 91 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP 194 122 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP 175 108 All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP 769 437 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037 673 All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE DN 409 268 All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973 570 All SZGR 2.0 genes in this pathway
MOSERLE IFNA RESPONSE 31 19 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
BOSCO INTERFERON INDUCED ANTIVIRAL MODULE 78 48 All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839 928 All SZGR 2.0 genes in this pathway
HECKER IFNB1 TARGETS 95 54 All SZGR 2.0 genes in this pathway