Gene Page:CDYL

概括?
基因 9425
Symbol CDYL
Synonyms CDYL1
Description chromodomain protein, Y-like
Reference MIM:603778|HGNC:HGNC:1811|Ensembl:ENSG00000153046|HPRD:04803|Vega:OTTHUMG00000014170
Gene type protein-coding
Map location 6p25.1
Pascal p-value 0.011
Sherlock p-value 0.833
eGene Hippocampus

数据源中的基因
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
GSMA_I Genome scan meta-analysis Psr: 0.0159

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26所示postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
sema4c 0.96 0.96
ZNF746 0.96 0.95
NUP62 0.96 0.97
ZNF317 0.95 0.94
SF1 0.95 0.96
KDM4A 0.95 0.94
EDC3 0.95 0.92
Qrich1 0.95 0.94
KDM2B 0.95 0.95
CSNK1E 0.95 0.93
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.31 -0.79 -0.90
MT-CO2 -0.77 -0.90
C5orf53 -0.76 -0.78
AF347015.27 -0.75 -0.87
AF347015.33 -0.74 -0.85
IFI27 -0.74 -0.85
FXYD1 -0.74 -0.85
MT-CYB -0.74 -0.86
S100B -0.73 -0.81
AF347015.8 -0.73 -0.88

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0003682 chromatin binding IEA -
GO:0004402 histone acetyltransferase activity IEA -
GO:0016740 transferase activity IEA -
去：0008415 acyltransferase activity IEA -
生物过程 去的术语 Evidence Neuro keywords PubMed ID
GO:0006333 chromatin assembly or disassembly IEA -
去：0006355 regulation of transcription, DNA-dependent IEA -
去：0006350 transcription IEA -
GO:0007283 spermatogenesis TAS 10192397
GO:0008152 metabolic process IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0000785 chromatin IEA -
GO:0005634 nucleus IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
DAVICIONI MOLECULAR ARMS VS ERMS UP 332 228 该途径中的所有SZGR 2.0基因
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579 346 该途径中的所有SZGR 2.0基因
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382 904 该途径中的所有SZGR 2.0基因
DOANE RESPONSE TO ANDROGEN DN 241 146 该途径中的所有SZGR 2.0基因
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278 748 该途径中的所有SZGR 2.0基因
BIDUS METASTASIS UP 214 134 该途径中的所有SZGR 2.0基因
RODRIGUES THYROID CARCINOMA ANAPLASTIC UP 722 443 该途径中的所有SZGR 2.0基因
BEGUM TARGETS OF PAX3 FOXO1 FUSION UP 60 45 该途径中的所有SZGR 2.0基因
DACOSTA UV RESPONSE VIA ERCC3 DN 855 609 该途径中的所有SZGR 2.0基因
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN 483 336 该途径中的所有SZGR 2.0基因
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN 584 395 该途径中的所有SZGR 2.0基因
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811 508 该途径中的所有SZGR 2.0基因
Benporath Nanog目标 988 594 该途径中的所有SZGR 2.0基因
BENPORATH OCT4 TARGETS 290 172 该途径中的所有SZGR 2.0基因
BENPORATH SOX2 TARGETS 734 436 该途径中的所有SZGR 2.0基因
BENPORATH NOS TARGETS 179 105 该途径中的所有SZGR 2.0基因
AMIT EGF RESPONSE 480 HELA 164 118 该途径中的所有SZGR 2.0基因
CUI TCF21 TARGETS 2 DN 830 547 该途径中的所有SZGR 2.0基因
DAZARD RESPONSE TO UV SCC DN 123 86 该途径中的所有SZGR 2.0基因
DAZARD RESPONSE TO UV NHEK DN 318 220 该途径中的所有SZGR 2.0基因
DAZARD UV RESPONSE CLUSTER G6 153 112 该途径中的所有SZGR 2.0基因
GENTILE UV RESPONSE CLUSTER D8 40 29 该途径中的所有SZGR 2.0基因
LIN MELANOMA COPY NUMBER UP 73 53 该途径中的所有SZGR 2.0基因
SMID BREAST CANCER BASAL UP 648 398 该途径中的所有SZGR 2.0基因
Bonome卵巢癌的生存次优秀 510 309 该途径中的所有SZGR 2.0基因
ALONSO METASTASIS UP 198 128 该途径中的所有SZGR 2.0基因
SHEDDEN LUNG CANCER POOR SURVIVAL A6 456 285 该途径中的所有SZGR 2.0基因
GYORFFY DOXORUBICIN RESISTANCE 56 34 该途径中的所有SZGR 2.0基因
PILON KLF1 TARGETS DN 1972 1213 该途径中的所有SZGR 2.0基因
JOHNSTONE PARVB TARGETS 2 DN 336 211 该途径中的所有SZGR 2.0基因
BRUINS UVC RESPONSE EARLY LATE 317 190 该途径中的所有SZGR 2.0基因
LEE BMP2 TARGETS DN 882 538 该途径中的所有SZGR 2.0基因
LIU IL13 PRIMING MODEL 15 11 该途径中的所有SZGR 2.0基因
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839 928 该途径中的所有SZGR 2.0基因

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
let-7/98 501 507 1A hsa-let-7abrain UGAGGUAGUAGGUUGUAUAGUU
hsa-let-7bbrain UGAGGUAGUAGGUUGUGUGGUU
hsa-let-7cbrain UGAGGUAGUAGGUUGUAUGGUU
hsa-let-7dbrain agagguaguagguugcauagu
hsa-let-7ebrain UGAGGUAGGAGGUUGUAUAGU
hsa-let-7fbrain UGAGGUAGUAGAUUGUAUAGUU
hsa-miR-98brain ugagguaaguuguauuguu
hsa-let-7gSZ UGAGGUAGUAGUUUGUACAGU
hsa-let-7ibrain UGAGGUAGUAGUUUGUGCUGU
miR-101 167 174 1A,m8 HSA-MIR-101 UACAGUACUGUGAUAACUGAAG
miR-144 168 174 1A hsa-miR-144 UACAGUAUAGAUGAUGUACUAG
miR-181 1216 1223 1A,m8 hsa-miR-181abrain aacauucaacgcugucggugagu
hsa-miR-181bSZ AACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrain AACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrain AACAUUCAUUGUUGUCGGUGGGUU
miR-196 1031 1037 m8 hsa-miR-196a UAGGUAGUUUCAUGUUGUUGG
hsa-miR-196b UAGGUAGUUUCCUGUUGUUGG
miR-200bc/429 1350 1356 m8 hsa-miR-200b UAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200c UAAUACUGCCGGGUAAUGAUGG
hsa-miR-429 UAAUACUGUCUGGUAAAACCGU
miR-27 1448 1454 1A hsa-miR-27abrain UUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrain UUCACAGUGGCUAAGUUCUGC
miR-329 1314 1320 1A hsa-miR-329brain AACACACCUGGUUAACCUCUUU
mir-370 39 45 1A hsa-miR-370brain GCCUGCUGGGGUGGAACCUGG
miR-485-3p 1220 1227 1A,m8 HSA-MIR-485-3P GUCAUACACGGCUCUCCUCUCU
mir-495 372 378 m8 hsa-miR-495brain AAACAAACAUGGUGCACUUCUUU