Gene Page:NAPSA
Summary?
| GeneID | 9476 |
| Symbol | NAPSA |
| Synonyms | KAP|Kdap|NAP1|NAPA|SNAPA |
| Description | napsin A aspartic peptidase |
| Reference | MIM:605631|HGNC:HGNC:13395|Ensembl:ENSG00000131400|HPRD:07064|Vega:OTTHUMG00000183035 |
| Gene type | protein-coding |
| Map location | 19q13.33 |
| Pascal p-value | 0.022 |
| Sherlock p-value | 2.433E-5 |
| Fetal beta | -0.256 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26页ostconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GLI3 | 0.90 | 0.46 |
| LTBP1 | 0.89 | 0.48 |
| TFAP2C | 0.89 | 0.50 |
| LIPG | 0.89 | 0.68 |
| TGIF2 | 0.88 | 0.47 |
| DMRTA2 | 0.87 | 0.51 |
| NOTCH1 | 0.86 | 0.51 |
| JUB | 0.86 | 0.47 |
| COL4A6 | 0.85 | 0.72 |
| GPC4 | 0.84 | 0.57 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.32 | -0.60 |
| FBXO2 | -0.32 | -0.49 |
| AIFM3 | -0.32 | -0.62 |
| HLA-F | -0.31 | -0.61 |
| AF347015.27 | -0.31 | -0.69 |
| S100B | -0.31 | -0.70 |
| AF347015.31 | -0.31 | -0.71 |
| AF347015.33 | -0.31 | -0.71 |
| ALDOC | -0.30 | -0.58 |
| FXYD1 | -0.30 | -0.70 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG LYSOSOME | 121 | 83 | All SZGR 2.0 genes in this pathway |
| MARKEY RB1 ACUTE LOF UP | 215 | 137 | All SZGR 2.0 genes in this pathway |
| SHETH LIVER CANCER VS TXNIP LOSS PAM1 | 229 | 137 | All SZGR 2.0 genes in this pathway |
| SCHAEFFER PROSTATE DEVELOPMENT 48HR UP | 487 | 286 | All SZGR 2.0 genes in this pathway |
| PASQUALUCCI LYMPHOMA BY GC STAGE DN | 165 | 104 | All SZGR 2.0 genes in this pathway |
| NING CHRONIC OBSTRUCTIVE PULMONARY DISEASE DN | 121 | 79 | All SZGR 2.0 genes in this pathway |
| SANSOM APC TARGETS DN | 366 | 238 | All SZGR 2.0 genes in this pathway |
| MATSUDA NATURAL KILLER DIFFERENTIATION | 475 | 313 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA D UP | 89 | 62 | All SZGR 2.0 genes in this pathway |
| GOLDRATH ANTIGEN RESPONSE | 346 | 192 | All SZGR 2.0 genes in this pathway |
| SWEET LUNG CANCER KRAS UP | 491 | 316 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 1 | 68 | 50 | All SZGR 2.0 genes in this pathway |
| SENGUPTA EBNA1 ANTICORRELATED | 173 | 85 | All SZGR 2.0 genes in this pathway |
| LI INDUCED T TO NATURAL KILLER UP | 307 | 182 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| HUANG GATA2 TARGETS UP | 149 | 96 | All SZGR 2.0 genes in this pathway |