SZGR2 - Beplay体育中心

Summary？

基因	948
象征	CD36
Synonyms	BDPLT10\|CHDS7\|FAT\|GP3B\|GP4\|GPIV\|PASIV\|SCARB3
Description	CD36分子
Reference	MIM:173510\|HGNC：HGNC：1663\|Ensembl:ENSG00000135218\|HPRD：01430\|Vega：Otthumg00000155383
基因类型	蛋白质编码
Map location	7q11.2
Pascal p-value	0.157
胎儿β	0.572

Gene in Data Sources

基因集名称	Method of gene set	Description	信息
CV:GWASdb	Genome-wide Association Studies	精神分裂症的GWASDB记录
CV:PGCnp	全基因组协会研究	GWAS
PMID：cooccur	High-throughput literature-search	PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	点击显示详细信息

Section I. Genetics and epigenetics annotation

第二节。转录组注释

一般基因表达（GTEX）

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

前10个积极共表达的基因
Gene	皮尔逊的相关性	斯皮尔曼的相关性
CD4	0.72	0.74
SLC40A1	0.70	0.63
IL13RA1	0.68	0.71
FZD6	0.68	0.67
IRF8	0.68	0.60
NCKAP1L	0.67	0.62
ano6	0.67	0.64
itga6	0.66	0.67
laptm5	0.66	0.63
PLOD2	0.66	0.66

Top 10 negatively co-expressed genes
Gene	皮尔逊的相关性	斯皮尔曼的相关性
ZNF814	-0.38	-0.41
AC132872.1	-0.38	-0.41
SNHG12	-0.34	-0.36
AL022328.1	-0.33	-0.36
EXD3	-0.33	-0.29
SLC7A9	-0.33	-0.33
ATAD3B	-0.33	-0.29
AC011511.1	-0.33	-0.28
AC040934.2	-0.32	-0.30
AC092143.1	-0.32	-0.34

Section IV. Protein-protein interaction annotation

互动者	别名b	官方全名b	实验	Source	PubMed ID
CD9	5H9 \| BA2 \| BTCC-1 \| DRAP-27 \| GIG2 \| MIC3 \| MRP-1 \| P24 \| TSPAN29	CD9分子	-	HPRD,BioGRID	11238109
Col1a1	OI4	collagen, type I, alpha 1	-	HPRD,BioGRID	2468670
Col1a2	OI4	collagen, type I, alpha 2	-	HPRD,BioGRID	10772928
Fyn	MGC45350 \| SLK \| SYN	Fyn Oncogene与SRC，FGR，是的	-	HPRD,BioGRID	7521304
HSD11B1	11-DH \|11-Beta-HSD1 \|HDL \|HSD11 \|HSD11B \|HSD11L \|MGC13539	羟基固醇（11-β）脱氢酶1	重构的复合物	Biogrid	9555943
itga2b	CD41 \| CD41B \| GP2B \| GPIIb \| GTA \| HPA3	整合素，α2B（IIB/IIIA复合物的血小板糖蛋白IIB，抗原CD41）	亲和力捕获 - 韦斯特恩	Biogrid	11238109
itga6	CD49F \|DKFZP686J01244 \|FLJ18737 \|itga6b \|VLA-6	integrin, alpha 6	亲和力捕获 - 韦斯特恩	Biogrid	11238109
ITGB1	CD29 \|fnrb \|GPIIA \|MDF2 \|MSK12 \|vla-beta \|vlab	整合素β1(纤连蛋白受体β息肉eptide, antigen CD29 includes MDF2, MSK12)	亲和力捕获 - 韦斯特恩	Biogrid	11238109
ITGB3	CD61 \| GP3A \| GPIIIa	整合素，β3（血小板糖蛋白IIIA，抗原CD61）	亲和力捕获 - 韦斯特恩	Biogrid	11238109
ldlr	FH \|FHC	low density lipoprotein receptor	重构的复合物	Biogrid	9555943
林恩	FLJ26625 \|JTK8	V-YES-1 Yamaguchi肉瘤病毒相关的癌基因同源物	-	HPRD,BioGRID	1715582
MATK	CHK \|CTK \|DKFZP434N1212 \|hhyltk \|hyl \|hyltk \|LSK \|MGC1708 \|MGC2101	巨核细胞相关的酪氨酸激酶	-	HPRD,BioGRID	9171348
src	ASV \| SRC1 \| c-SRC \| p60-Src	V-SRC肉瘤（Schmidt-Ruppin A-2）病毒癌基因同源物（Avian）	-	HPRD	7521304
THBS1	THBS \| TSP \| TSP1	thrombospondin 1	-	HPRD	10487979\|10772961
vldlr	chrmq1 \|FLJ35024 \|vldlrch	非常低密度脂蛋白受体	重构的复合物	Biogrid	9555943
是的1	HST441 \|p61-yes \|是\|c-yes	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	-	HPRD	7521304
是的1	HST441 \|p61-yes \|是\|c-yes	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	亲和力捕获 - 韦斯特恩	Biogrid	1715582

Section V. Pathway annotation

路径名	路径大小	# SZGR 2.0 genes in pathway	信息
kegg ppar信号通路	69	47	All SZGR 2.0 genes in this pathway
KEGG ECM受体相互作用	84	53	All SZGR 2.0 genes in this pathway
KEGG造血细胞谱系	88	60	All SZGR 2.0 genes in this pathway
KEGG ADIPOCYTOKINE SIGNALING PATHWAY	67	57	All SZGR 2.0 genes in this pathway
Biocarta PPARA途径	58	43	All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY	396	292	All SZGR 2.0 genes in this pathway
Reactome抗原加工交叉呈现	76	48	All SZGR 2.0 genes in this pathway
Reactome Ppara激活基因表达	104	72	All SZGR 2.0 genes in this pathway
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	89	56	All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS	478	302	All SZGR 2.0 genes in this pathway
反应组脂肪酸三酰甘油和酮体代谢	168	115	All SZGR 2.0 genes in this pathway
白色脂肪细胞分化的Reactome转录调节	72	53	All SZGR 2.0 genes in this pathway
反应组止血	466	331	All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM	933	616	All SZGR 2.0 genes in this pathway
Reactome适应性免疫系统	539	350	All SZGR 2.0 genes in this pathway
Reactome I类MHC介导的抗原加工表现	251	156	All SZGR 2.0 genes in this pathway
Reactome血小板激活信号传导和聚集	208	138	All SZGR 2.0 genes in this pathway
turashvili乳房小叶癌与小叶正常	94	59	All SZGR 2.0 genes in this pathway
Fulcher炎症反应凝集素与LPS DN	463	290	All SZGR 2.0 genes in this pathway
THUM收缩心力衰竭DN	244	147	All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病	1382	904	All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN	367	220	All SZGR 2.0 genes in this pathway
runx1 runx1t1融合HSC DN的TONKS目标	187	115	All SZGR 2.0 genes in this pathway
剑麻结肠直肠腺瘤DN	291	176	All SZGR 2.0 genes in this pathway
JAATINEN HEMATOPOIETIC STEM CELL DN	226	132	All SZGR 2.0 genes in this pathway
GRAHAM CML QUIESCENT VS NORMAL QUIESCENT UP	87	45	All SZGR 2.0 genes in this pathway
Graham CML分割与正常静止	181	101	All SZGR 2.0 genes in this pathway
Graham正常静止与正常分裂DN	87	49	All SZGR 2.0 genes in this pathway
ENK UV响应表皮增强	293	179	All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN	232	154	All SZGR 2.0 genes in this pathway
landis erbb2乳房肿瘤型DN	55	33	All SZGR 2.0 genes in this pathway
Landis Erbb2乳腺肿瘤324 DN	149	93	All SZGR 2.0 genes in this pathway
EBAUER TARGETS OF PAX3 FOXO1 FUSION UP	207	128	All SZGR 2.0 genes in this pathway
Mohankumar TLX1靶向	414	287	All SZGR 2.0 genes in this pathway
Pujana ATM PCC网络	1442	892	All SZGR 2.0 genes in this pathway
里克曼肿瘤分化了井和DN不良	382	224	All SZGR 2.0 genes in this pathway
MORI SMALL PRE BII LYMPHOCYTE DN	76	52	All SZGR 2.0 genes in this pathway
李肝癌电抗	60	42	All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS	882	572	All SZGR 2.0 genes in this pathway
DORSAM HOXA9靶向DN	32	22	All SZGR 2.0 genes in this pathway
Schuringa Stat5A靶向	21	13	All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION	475	313	All SZGR 2.0 genes in this pathway
亚伯拉罕ALPC与多发性骨髓瘤	26	22	All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED UP	183	111	All SZGR 2.0 genes in this pathway
KANG IMMORTALIZED BY TERT UP	89	61	All SZGR 2.0 genes in this pathway
Jazaeri乳腺癌BRCA1 vs BRCA2 DN	43	31	All SZGR 2.0 genes in this pathway
CUI TCF21目标2 DN	830	547	All SZGR 2.0 genes in this pathway
Chiba对TSA的反应	52	33	All SZGR 2.0 genes in this pathway
CHEN ETV5 TARGETS SERTOLI	20	10	All SZGR 2.0 genes in this pathway
Kaab心脏中心与心室DN	261	183	All SZGR 2.0 genes in this pathway
ZAMORA NOS2 TARGETS DN	96	71	All SZGR 2.0 genes in this pathway
Weng Por靶向肝脏	41	29	All SZGR 2.0 genes in this pathway
Gerhold脂肪形成	49	40	All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY 4NQO	38	24	All SZGR 2.0 genes in this pathway
Kyng DNA损伤DN	195	135	All SZGR 2.0 genes in this pathway
ZHANG GATA6 TARGETS UP	15	12	All SZGR 2.0 genes in this pathway
马丁内斯RB1靶向	673	430	All SZGR 2.0 genes in this pathway
Martinez RB1靶向DN	543	317	All SZGR 2.0 genes in this pathway
Martinez TP53靶向	602	364	All SZGR 2.0 genes in this pathway
Martinez RB1和TP53靶向	601	369	All SZGR 2.0 genes in this pathway
Massarweh tamoxifen抗性	578	341	All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP	430	288	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN	701	446	All SZGR 2.0 genes in this pathway
Zheng胶质母细胞瘤可塑性	250	168	All SZGR 2.0 genes in this pathway
GRADE COLON CANCER DN	33	22	All SZGR 2.0 genes in this pathway
ERBB2 CDC25A的射线肿瘤发生	104	57	All SZGR 2.0 genes in this pathway
CADWELL ATG16L1靶向	93	56	All SZGR 2.0 genes in this pathway
VART KSHV感染血管生成标记DN	138	92	All SZGR 2.0 genes in this pathway
HOFFMANN SMALL PRE BII TO IMMATURE B LYMPHOCYTE UP	70	49	All SZGR 2.0 genes in this pathway
霍夫曼不成熟到成熟的B淋巴细胞DN	50	36	All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK	1210	725	All SZGR 2.0 genes in this pathway
Liu Vav3前列腺致癌作用	89	61	All SZGR 2.0 genes in this pathway
ROME INSULIN TARGETS IN MUSCLE UP	442	263	All SZGR 2.0 genes in this pathway
清肝癌子类CTNNB1 UP	176	110	All SZGR 2.0 genes in this pathway
Nakayama软组织肿瘤PCA2 DN	80	51	All SZGR 2.0 genes in this pathway
中村脂肪形成晚期	104	67	All SZGR 2.0 genes in this pathway
霍夫曼时钟定位	11	7	All SZGR 2.0 genes in this pathway
WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP	397	206	All SZGR 2.0 genes in this pathway
WANG CLASSIC ADIPOGENIC TARGETS OF PPARG	26	15	All SZGR 2.0 genes in this pathway
Ohguchi肝HNF4A靶向	44	30	All SZGR 2.0 genes in this pathway
STEGER ADIPOGENESIS UP	21	16	All SZGR 2.0 genes in this pathway
FEVR CTNNB1靶向	682	433	All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D	882	506	All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 10HR DN	244	157	All SZGR 2.0 genes in this pathway
桑德森PPARA目标	15	7	All SZGR 2.0 genes in this pathway
GUILLAUMOND KLF10 TARGETS DN	30	15	All SZGR 2.0 genes in this pathway
林乳腺干细胞向上	489	314	All SZGR 2.0 genes in this pathway

Gene Page:CD36