Gene Page:BAG5

Summary?
GeneID 9529
Symbol BAG5
Synonyms BAG-5
Description BCL2 associated athanogene 5
Reference MIM:603885|HGNC:HGNC:941|Ensembl:ENSG00000166170|HPRD:04862|Vega:OTTHUMG00000171763
Gene type protein-coding
Map location 14q32.33
Pascal p-value 6.885E-12
Sherlock p-value 0.183
Fetal beta 0.926
DMG 1 (# studies)

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 2

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg25595571 14 104029029 BAG5;C14orf153 2.59E-5 -0.341 0.017 DMG:Wockner_2014
cg18473379 14 104027293 BAG5 1.89E-4 0.534 0.034 DMG:Wockner_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception一周s), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AMIGO1 0.93 0.94
ZER1 0.92 0.92
ATG9A 0.91 0.91
ABR 0.91 0.91
NFE2L1 0.90 0.90
MADD 0.90 0.89
STXBP1 0.89 0.92
NPLOC4 0.89 0.90
DAGLA 0.89 0.91
KIAA1467 0.89 0.90
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.21 -0.60 -0.53
GNG11 -0.55 -0.54
AL139819.3 -0.54 -0.55
C1orf54 -0.53 -0.58
DBI -0.52 -0.61
AF347015.18 -0.52 -0.47
AP002478.3 -0.52 -0.52
AF347015.31 -0.50 -0.46
AF347015.8 -0.50 -0.45
NSBP1 -0.49 -0.50

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
ONKEN UVEAL MELANOMA DN 526 357 All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS DN 431 263 All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP 233 161 All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278 748 All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821 933 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN 805 505 All SZGR 2.0 genes in this pathway
LAU APOPTOSIS CDKN2A UP 55 40 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION DN 234 147 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 1781 1082 All SZGR 2.0 genes in this pathway
HEIDENBLAD AMPLICON 8Q24 UP 40 23 All SZGR 2.0 genes in this pathway
JAZAG TGFB1 SIGNALING UP 108 69 All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS DN 848 527 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS DN 637 377 All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988 594 All SZGR 2.0 genes in this pathway
BENPORATH OCT4 TARGETS 290 172 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237 837 All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV SCC DN 123 86 All SZGR 2.0 genes in this pathway
LIN MELANOMA COPY NUMBER DN 41 34 All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA D UP 89 62 All SZGR 2.0 genes in this pathway
SETLUR PROSTATE CANCER TMPRSS2 ERG FUSION UP 67 48 All SZGR 2.0 genes in this pathway
PYEON CANCER HEAD AND NECK VS CERVICAL UP 193 95 All SZGR 2.0 genes in this pathway