Gene Page:KIAA0355

Summary?
GeneID 9710
Symbol KIAA0355
Synonyms -
Description KIAA0355
Reference HGNC:HGNC:29016|Ensembl:ENSG00000166398|HPRD:11077|Vega:OTTHUMG00000180505
Gene type protein-coding
Map location 19q13.11
Pascal p-value 0.146
Sherlock p-value 0.762
Fetal beta 1.041
DMG 1 (# studies)
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Montano_2016 Genome-wide DNA methylation analysis This dataset includes 172 replicated associations between CpGs with schizophrenia. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg07458272 19 34744396 KIAA0355 5.39E-7 0.01 0.014 DMG:Montano_2016

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs16829545 chr2 151977407 KIAA0355 9710 0.02 trans
rs10965049 chr9 21526525 KIAA0355 9710 0.05 trans
rs3118341 chr9 25185518 KIAA0355 9710 0.08 trans
rs2393316 chr10 59333070 KIAA0355 9710 0.09 trans
rs16955618 chr15 29937543 KIAA0355 9710 3.352E-4 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
ENTPD6 0.91 0.91
GRIN1 0.90 0.93
MAN2B2 0.90 0.89
DCTN1 0.89 0.92
PLD3 0.89 0.90
CLSTN3 0.88 0.90
SLC25A22 0.88 0.90
PTPRN 0.88 0.90
AP001107.1 0.88 0.89
IGSF8 0.88 0.89
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
GNG11 -0.45 -0.41
AF347015.21 -0.44 -0.27
AF347015.18 -0.43 -0.27
AP002478.3 -0.43 -0.39
FAM159B -0.43 -0.63
RAB13 -0.42 -0.50
NSBP1 -0.42 -0.41
AL139819.3 -0.41 -0.39
MYL12A -0.41 -0.44
AL050337.1 -0.40 -0.39

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
OSMAN BLADDER CANCER DN 406 230 All SZGR 2.0 genes in this pathway
PATIL LIVER CANCER 747 453 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442 892 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811 508 All SZGR 2.0 genes in this pathway
KOYAMA SEMA3B TARGETS UP 292 168 All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS UP 424 268 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953 554 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783 442 All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN UP 439 257 All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL DN 216 143 All SZGR 2.0 genes in this pathway
VERHAAK GLIOBLASTOMA CLASSICAL 162 122 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP 504 321 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway