Gene Page:CCP110
Summary?
| GeneID | 9738 |
| Symbol | CCP110 |
| Synonyms | CP110|Cep110 |
| Description | centriolar coiled-coil protein 110kDa |
| Reference | MIM:609544|HGNC:HGNC:24342|Ensembl:ENSG00000103540|HPRD:10848|Vega:OTTHUMG00000131459 |
| Gene type | protein-coding |
| Map location | 16p12.3 |
| Pascal p-value | 0.037 |
| Sherlock p-value | 0.838 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ATG2B | 0.87 | 0.86 |
| TTBK2 | 0.85 | 0.84 |
| DMXL1 | 0.84 | 0.83 |
| VPS13D | 0.84 | 0.84 |
| RAPGEF2 | 0.84 | 0.86 |
| SLC35B4 | 0.84 | 0.83 |
| RRM2B | 0.83 | 0.82 |
| HIPK3 | 0.83 | 0.83 |
| GARNL1 | 0.83 | 0.83 |
| ESYT2 | 0.83 | 0.85 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C1orf61 | -0.54 | -0.65 |
| DBI | -0.53 | -0.62 |
| C1orf54 | -0.51 | -0.57 |
| ENHO | -0.50 | -0.55 |
| AF347015.21 | -0.49 | -0.49 |
| RHOC | -0.49 | -0.57 |
| RAB34 | -0.49 | -0.55 |
| VAMP5 | -0.48 | -0.48 |
| SERF2 | -0.48 | -0.53 |
| C16orf74 | -0.48 | -0.53 |
Section III. Gene Ontology annotation
| Molecular function | 去term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005515 | protein binding | 新闻学会 | 16760425 | |
| Biological process | 去term | Evidence | Neuro keywords | PubMed ID |
| GO:0051298 | centrosome duplication | IMP | 16760425 | |
| GO:0032465 | regulation of cytokinesis | IMP | 16760425 | |
| Cellular component | 去term | Evidence | Neuro keywords | PubMed ID |
| GO:0005813 | centrosome | IDA | 16760425 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DAVICIONI MOLECULAR ARMS VS ERMS UP | 332 | 228 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER UP | 227 | 137 | All SZGR 2.0 genes in this pathway |
| RICKMAN METASTASIS UP | 344 | 180 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS MATURE CELL | 293 | 160 | All SZGR 2.0 genes in this pathway |
| DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP | 314 | 201 | All SZGR 2.0 genes in this pathway |
| MARIADASON REGULATED BY HISTONE ACETYLATION UP | 83 | 49 | All SZGR 2.0 genes in this pathway |
| BILD E2F3 ONCOGENIC SIGNATURE | 246 | 153 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 | 473 | 224 | All SZGR 2.0 genes in this pathway |
| LEIN OLIGODENDROCYTE MARKERS | 74 | 53 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY E2F4 UNSTIMULATED | 728 | 415 | All SZGR 2.0 genes in this pathway |
| EHLERS ANEUPLOIDY UP | 41 | 29 | All SZGR 2.0 genes in this pathway |
| FEVR CTNNB1 TARGETS DN | 553 | 343 | All SZGR 2.0 genes in this pathway |
| KOINUMA TARGETS OF SMAD2 OR SMAD3 | 824 | 528 | All SZGR 2.0 genes in this pathway |
| DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |
| DELACROIX RAR BOUND ES | 462 | 273 | All SZGR 2.0 genes in this pathway |
| RAO BOUND BY SALL4 ISOFORM B | 517 | 302 | All SZGR 2.0 genes in this pathway |
| SMIRNOV RESPONSE TO IR 6HR UP | 166 | 97 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |