Gene Page:SNPH

Summary?
GeneID 9751
Symbol SNPH
Synonyms -
Description syntaphilin
Reference MIM:604942|HGNC:HGNC:15931|Ensembl:ENSG00000101298|HPRD:16081|Vega:OTTHUMG00000031662
Gene type protein-coding
Map location 20p13
Pascal p-value 0.008
Sherlock p-value 0.05
Fetal beta -1.807
eGene Cerebellar Hemisphere
Support CANABINOID
DOPAMINE
SEROTONIN
CompositeSet
Darnell FMRP targets

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
GO_Annotation Mapping neuro-related keywords to Gene Ontology annotations Hits with neuro-related keywords: 3

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AGPAT3 0.92 0.93
NFE2L1 0.91 0.92
SIDT2 0.89 0.89
SPATA2 0.89 0.89
TBC1D9B 0.89 0.90
AP006216.1 0.88 0.93
TOM1L2 0.88 0.88
ATG9A 0.88 0.88
ZBTB4 0.87 0.91
AMIGO1 0.87 0.87
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
C8orf59 -0.56 -0.54
GNG11 -0.55 -0.51
AL050337.1 -0.54 -0.53
ST20 -0.54 -0.57
PFDN5 -0.54 -0.52
SYCP3 -0.53 -0.51
C1orf54 -0.53 -0.45
RPL31 -0.52 -0.57
RPL35 -0.51 -0.56
C1orf61 -0.51 -0.46

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0017075 syntaxin-1 binding NAS 10707983
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0007269 neurotransmitter secretion NAS neuron, axon, Synap, serotonin, Neurotransmitter, dopamine (GO term level: 8) 10707983
GO:0016081 synaptic vesicle docking during exocytosis NAS Synap (GO term level: 10) 10707983
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0019717 synaptosome IEA Synap, Brain (GO term level: 7) -
GO:0045202 synapse IEA neuron, Synap, Neurotransmitter, Glial (GO term level: 2) -
GO:0016020 membrane IEA -
GO:0016021 integral to membrane IEA -
GO:0030054 cell junction IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
DOANE RESPONSE TO ANDROGEN DN 241 146 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER ERBB2 UP 147 83 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701 446 All SZGR 2.0 genes in this pathway
ACOSTA PROLIFERATION INDEPENDENT MYC TARGETS DN 116 74 All SZGR 2.0 genes in this pathway
PURBEY TARGETS OF CTBP1 NOT SATB1 DN 448 282 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-130/301 1022 1029 1A,m8 hsa-miR-130abrain CAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301 CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrain CAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3p UAGUGCAAUAUUGCUUAUAGGGUUU
miR-148/152 1637 1643 m8 hsa-miR-148a UCAGUGCACUACAGAACUUUGU
hsa-miR-152brain UCAGUGCAUGACAGAACUUGGG
hsa-miR-148b UCAGUGCAUCACAGAACUUUGU
miR-19 1021 1027 m8 hsa-miR-19a UGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19b UGUGCAAAUCCAUGCAAAACUGA
miR-331 3152 3158 1A hsa-miR-331brain GCCCCUGGGCCUAUCCUAGAA
miR-346 3237 3243 1A hsa-miR-346brain UGUCUGCCCGCAUGCCUGCCUCU
miR-485-3p 1970 1977 1A,m8 hsa-miR-485-3p GUCAUACACGGCUCUCCUCUCU