Gene Page:PCDHA9
Summary?
| GeneID | 9752 |
| Symbol | PCDHA9 |
| Synonyms | PCDH-ALPHA9 |
| Description | protocadherin alpha 9 |
| Reference | MIM:606315|HGNC:HGNC:8675|Ensembl:ENSG00000204961|HPRD:07327|Vega:OTTHUMG00000163373 |
| Gene type | protein-coding |
| Map location | 5q31 |
| Pascal p-value | 8.753E-6 |
| eGene | Cerebellar Hemisphere 小脑 Cortex Frontal Cortex BA9 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.0032 | |
| Expression | Meta-analysis of gene expression | Pvalue: 1.517 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ATAD1 | 0.85 | 0.84 |
| IMMT | 0.84 | 0.87 |
| STAU2 | 0.84 | 0.85 |
| GPRASP2 | 0.84 | 0.82 |
| CUL2 | 0.83 | 0.85 |
| NRD1 | 0.83 | 0.85 |
| RPS6KC1 | 0.83 | 0.82 |
| MTMR2 | 0.83 | 0.83 |
| PSMD1 | 0.83 | 0.85 |
| SERAC1 | 0.83 | 0.85 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.69 | -0.66 |
| AF347015.31 | -0.69 | -0.67 |
| AF347015.21 | -0.68 | -0.64 |
| AF347015.8 | -0.68 | -0.66 |
| AF347015.2 | -0.67 | -0.65 |
| AF347015.33 | -0.65 | -0.64 |
| MT-CYB | -0.65 | -0.63 |
| AF347015.15 | -0.64 | -0.64 |
| HIGD1B | -0.64 | -0.64 |
| AF347015.27 | -0.63 | -0.63 |
Section III. Gene Ontology annotation
| Molecular function | 去的术语 | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005509 | calcium ion binding | IEA | - | |
| GO:0005515 | protein binding | IEA | - | |
| Biological process | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0007155 | cell adhesion | IEA | - | |
| GO:0007156 | homophilic cell adhesion | IEA | - | |
| Cellular component | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0016021 | integral to membrane | IEA | - | |
| GO:0005886 | plasma membrane | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| RODWELL AGING KIDNEY NO BLOOD UP | 222 | 139 | All SZGR 2.0 genes in this pathway |
| RODWELL AGING KIDNEY UP | 487 | 303 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN IPS HCP WITH H3 UNMETHYLATED | 80 | 50 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES HCP WITH H3 UNMETHYLATED | 63 | 31 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF HCP WITH H3 UNMETHYLATED | 228 | 119 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN PREDNISOLONE RESISTANCE B ALL DN | 12 | 8 | All SZGR 2.0 genes in this pathway |