Gene Page:ATG13
Summary?
| GeneID | 9776 |
| Symbol | ATG13 |
| Synonyms | KIAA0652|PARATARG8 |
| Description | autophagy related 13 |
| Reference | MIM:615088|HGNC:HGNC:29091|Ensembl:ENSG00000175224|HPRD:13809|Vega:OTTHUMG00000166538 |
| Gene type | protein-coding |
| Map location | 11p11.2 |
| Pascal p-value | 3.472E-9 |
| Sherlock p-value | 0.342 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs2370688 | chr2 | 187298695 | ATG13 | 9776 | 0.19 | trans | ||
| rs10497672 | 0 | ATG13 | 9776 | 0.03 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26conception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RP11-454H13.1 | 0.88 | 0.89 |
| ADO | 0.87 | 0.92 |
| SFRS2B | 0.86 | 0.88 |
| EGLN1 | 0.85 | 0.91 |
| AL133445.3 | 0.85 | 0.86 |
| ZXDB | 0.85 | 0.88 |
| FOXO3 | 0.84 | 0.89 |
| NAT12 | 0.83 | 0.89 |
| AC025287.3 | 0.83 | 0.89 |
| OTUD1 | 0.82 | 0.91 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.55 | -0.70 |
| SERPINB6 | -0.55 | -0.62 |
| MT-CO2 | -0.55 | -0.71 |
| FXYD1 | -0.53 | -0.66 |
| HIGD1B | -0.53 | -0.68 |
| COPZ2 | -0.53 | -0.63 |
| AF347015.21 | -0.53 | -0.75 |
| AF347015.8 | -0.52 | -0.69 |
| MT-CYB | -0.52 | -0.66 |
| S100A16 | -0.52 | -0.63 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PID MTOR 4PATHWAY | 69 | 55 | All SZGR 2.0 genes in this pathway |
| WANG CLIM2 TARGETS UP | 269 | 146 | All SZGR 2.0 genes in this pathway |
| NUYTTEN NIPP1 TARGETS DN | 848 | 527 | All SZGR 2.0 genes in this pathway |
| KOYAMA SEMA3B TARGETS UP | 292 | 168 | All SZGR 2.0 genes in this pathway |
| BENPORATH NANOG TARGETS | 988 | 594 | All SZGR 2.0 genes in this pathway |
| ROSS AML WITH PML RARA FUSION | 77 | 62 | All SZGR 2.0 genes in this pathway |
| WANG CISPLATIN RESPONSE AND XPC DN | 228 | 146 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 48HR DN | 504 | 323 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| YAUCH HEDGEHOG SIGNALING PARACRINE DN | 264 | 159 | All SZGR 2.0 genes in this pathway |
| ROME INSULIN TARGETS IN MUSCLE DN | 204 | 114 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| MIZUSHIMA AUTOPHAGOSOME FORMATION | 19 | 15 | All SZGR 2.0 genes in this pathway |