Gene Page:ARHGAP44
Summary?
| GeneID | 9912 |
| Symbol | ARHGAP44 |
| Synonyms | NPC-A-10|RICH2 |
| Description | Rho GTPase activating protein 44 |
| Reference | HGNC:HGNC:29096|Ensembl:ENSG00000006740|HPRD:13810|Vega:OTTHUMG00000058765 |
| Gene type | protein-coding |
| Map location | 17p12 |
| Pascal p-value | 4.095E-5 |
| Sherlock p-value | 0.931 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 -26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| EZH1 | 0.84 | 0.87 |
| WDR42A | 0.82 | 0.81 |
| PNMA3 | 0.81 | 0.82 |
| SGSM1 | 0.80 | 0.83 |
| HACE1 | 0.80 | 0.84 |
| MAN2A2 | 0.80 | 0.83 |
| SPATA2 | 0.80 | 0.81 |
| MAPK8IP3 | 0.80 | 0.83 |
| KLHL3 | 0.79 | 0.82 |
| COG1 | 0.79 | 0.84 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| GNG11 | -0.51 | -0.60 |
| IL32 | -0.51 | -0.59 |
| DBI | -0.51 | -0.59 |
| MYL12A | -0.50 | -0.58 |
| AF347015.21 | -0.49 | -0.47 |
| CLEC3B | -0.48 | -0.58 |
| IGFBP7 | -0.48 | -0.57 |
| C1orf54 | -0.48 | -0.55 |
| RHOC | -0.48 | -0.57 |
| S100A16 | -0.47 | -0.50 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME SIGNALING BY RHO GTPASES | 113 | 81 | All SZGR 2.0 genes in this pathway |
| HUTTMANN B CLL POOR SURVIVAL UP | 276 | 187 | All SZGR 2.0 genes in this pathway |
| BORCZUK MALIGNANT MESOTHELIOMA DN | 104 | 59 | All SZGR 2.0 genes in this pathway |
| HAMAI APOPTOSIS VIA TRAIL UP | 584 | 356 | All SZGR 2.0 genes in this pathway |
| PEREZ TP53 TARGETS | 1174 | 695 | All SZGR 2.0 genes in this pathway |
| MOREAUX MULTIPLE MYELOMA BY TACI UP | 412 | 249 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 20HR UP | 240 | 152 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 | 720 | 440 | All SZGR 2.0 genes in this pathway |
| MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 | 142 | 103 | All SZGR 2.0 genes in this pathway |
| WANG RESPONSE TO GSK3 INHIBITOR SB216763 DN | 374 | 217 | All SZGR 2.0 genes in this pathway |
| FIGUEROA AML METHYLATION CLUSTER 1 UP | 125 | 61 | All SZGR 2.0 genes in this pathway |
| FIGUEROA AML METHYLATION CLUSTER 2 UP | 54 | 31 | All SZGR 2.0 genes in this pathway |
| FIGUEROA AML METHYLATION CLUSTER 3 UP | 170 | 97 | All SZGR 2.0 genes in this pathway |