Gene Page:OXSR1

概括?
基因 9943
Symbol OXSR1
Synonyms OSR1
Description oxidative stress responsive 1
Reference MIM:604046|HGNC:HGNC:8508|Ensembl:ENSG00000172939|HPRD:06809|Vega:OTTHUMG00000131084
Gene type protein-coding
Map location 3p22.2
Pascal p-value 0.312
Fetal beta 0.937

数据源中的基因
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
GSMA_I Genome scan meta-analysis PSR：0.006
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0000166 nucleotide binding IEA -
GO:0000287 magnesium ion binding IDA 14707132
GO:0005524 ATP binding IDA 14707132
GO:0004674 蛋白质丝氨酸/苏氨酸激酶活性 IDA 14707132
GO:0016740 transferase activity IEA -
GO:0042802 identical protein binding 新闻学会 17353931
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006468 protein amino acid phosphorylation IDA 14707132
GO:0007243 protein kinase cascade IDA 14707132
GO:0006979 response to oxidative stress TAS 10083736
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005737 cytoplasm IDA 18029348

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
HOLLMANN APOPTOSIS VIA CD40 DN 267 178 All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382 904 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS DN 508 354 All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800 473 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN 483 336 All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN 584 395 All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 1652 1023 All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442 892 All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC NETWORK 779 480 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037 673 All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN 382 224 All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY DN 110 64 All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND UP 77 52 All SZGR 2.0 genes in this pathway
《图片报》极品致癌签名 261 166 All SZGR 2.0 genes in this pathway
肌肉中的罗马胰岛素靶标 442 263 All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION 368 247 All SZGR 2.0 genes in this pathway
BILANGES RAPAMYCIN SENSITIVE GENES 39 20 All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 36HR 152 88 All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D 882 506 All SZGR 2.0 genes in this pathway
KRIEG HYPOXIA NOT VIA KDM3A 770 480 All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF 516 308 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-124.1 647 653 1A hsa-miR-124a UUAAGGCACGCGGUGAAUGCCA
hsa-miR-124a UUAAGGCACGCGGUGAAUGCCA
hsa-miR-124a UUAAGGCACGCGGUGAAUGCCA
miR-124/506 309 315 1A hsa-miR-506 UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brain UAAGGCACGCGGUGAAUGCC
mir-137 932 938 1A hsa-miR-137 UAUUGCUUAAGAAUACGCGUAG
miR-148/152 987 994 1A,m8 hsa-miR-148a UCAGUGCACUACAGAACUUUGU
hsa-miR-152brain UCAGUGCAUGACAGAACUUGGG
hsa-miR-148b UCAGUGCAUCACAGAACUUUGU
miR-149 2408 2414 m8 hsa-miR-149brain UCUGGCUCCGUGUCUUCACUCC
miR-182 81 87 1A hsa-miR-182 UUUGGCAAUGGUAGAACUCACA
miR-186 1122 1129 1A,m8 hsa-miR-186 CAAAGAAUUCUCCUUUUGGGCUU
miR-191 209 216 1A,m8 hsa-miR-191brain CAACGGAAUCCCAAAAGCAGCU
miR-218 2306 2312 1A hsa-miR-218brain UUGUGCUUGAUCUAACCAUGU
hsa-miR-218brain UUGUGCUUGAUCUAACCAUGU
miR-25/32/92/363/367 1153 1159 1A hsa-miR-25brain CAUUGCACUUGUCUCGGUCUGA
hsa-miR-32 UAUUGCACAUUACUAAGUUGC
hsa-miR-92 UAUUGCACUUGUCCCGGCCUG
hsa-miR-367 aauugcacuuuagcaaugguga
hsa-miR-92bSZ UAUUGCACUCGUCCCGGCCUC
miR-31 306 312 m8 hsa-miR-31 AGGCAAGAUGCUGGCAUAGCUG
miR-320 116 122 1A hsa-miR-320 AAAAGCUGGGUUGAGAGGGCGAA
miR-324-3p 2149 2155 1A HSA-MIR-324-3P CCACUGCCCCAGGUGCUGCUGG
miR-326 453 460 1A,m8 hsa-miR-326 CCUCUGGGCCCUUCCUCCAG
miR-33 1151 1157 1A hsa-miR-33 GUGCAUUGUAGUUGCAUUG
hsa-miR-33b GUGCAUUGCUGUUGCAUUGCA
miR-34/449 79 85 1A hsa-miR-34abrain UGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34c AGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449 UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449b AGGCAGUGUAUUGUUAGCUGGC
miR-485-5p 526 533 1A,m8 hsa-miR-485-5p AGAGGCUGGCCGUGAUGAAUUC
mir-495 509 515 1A hsa-miR-495brain AAACAAACAUGGUGCACUUCUUU
mir-496 2503 2509 1A hsa-miR-496 AUUACAUGGCCAAUCUC
miR-9 83 89 1A hsa-miR-9SZ UCUUUGGUUAUCUAGCUGUAUGA
mir-96 81 87 1A hsa-miR-96brain UUUGGCACUAGCACAUUUUUGC
hsa-miR-96brain UUUGGCACUAGCACAUUUUUGC