Gene Page:CSMD1

Summary?
GeneID 64478
Symbol CSMD1
Synonyms PPP1R24
Description CUB and Sushi multiple domains 1
Reference MIM:608397|HGNC:HGNC:14026|Ensembl:ENSG00000183117|HPRD:10523|Vega:OTTHUMG00000163605
Gene type protein-coding
Map location 8p23.2
Sherlock p-value 0.929
Fetal beta -0.184
eGene Myers' cis & trans
元

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWAScat Genome-wide Association Studies This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGC128 Genome-wide Association Study A multi-stage schizophrenia GWAS of up to 36,989 cases and 113,075 controls. Reported by the Schizophrenia Working Group of PGC. 128 independent associations spanning 108 loci
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance与Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@CV:PGC128

SNP ID Chromosome Position Allele P Function Gene Up/Down Distance
rs10503253 chr8 4180844 AC 2.694E-8 intronic CSMD1

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs17029291 chr3 32402138 CSMD1 64478 0 trans
rs7078127 chr10 74847633 CSMD1 64478 0.08 trans
rs12569493 chr10 74886042 CSMD1 64478 0.06 trans
rs16930362 chr10 74890320 CSMD1 64478 0 trans
rs7092445 chr10 74921991 CSMD1 64478 0.02 trans
rs12256576 chr10 74934313 CSMD1 64478 0.1 trans
rs1867565 chr10 74977780 CSMD1 64478 0.02 trans
rs11000557 chr10 74987393 CSMD1 64478 0.03 trans
rs12569470 chr10 74995826 CSMD1 64478 0.1 trans
rs16915029 chr10 75001994 CSMD1 64478 0.03 trans
rs14488 chr10 75007274 CSMD1 64478 0.06 trans
rs16930466 chr10 75007587 CSMD1 64478 0.04 trans
rs11000579 chr10 75027961 CSMD1 64478 0.01 trans
rs11000594 chr10 75064566 CSMD1 64478 0.14 trans
rs11000607 chr10 75089777 CSMD1 64478 0 trans
rs6480700 chr10 75101689 CSMD1 64478 0.07 trans
rs16930573 chr10 75167645 CSMD1 64478 0.14 trans
rs12571454 chr10 75208954 CSMD1 64478 0.03 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
HATADA METHYLATED IN LUNG CANCER UP 390 236 All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038 678 All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062 725 All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652 441 All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 142 103 All SZGR 2.0 genes in this pathway
MIKKELSEN NPC HCP WITH H3K4ME3 AND H3K27ME3 210 148 All SZGR 2.0 genes in this pathway
MIKKELSEN MEF HCP WITH H3K27ME3 590 403 All SZGR 2.0 genes in this pathway
PEDRIOLI MIR31 TARGETS UP 221 120 All SZGR 2.0 genes in this pathway