Gene Page:NTM

Summary?
GeneID 50863
Symbol NTM
Synonyms HNT|IGLON2|NTRI
Description neurotrimin
Reference MIM:607938|HGNC:HGNC:17941|Ensembl:ENSG00000182667|HPRD:06398|Vega:OTTHUMG00000066364
Gene type protein-coding
Map location 11q25
Pascal p-value 0.008
Fetal beta -1.22
DMG 1 (# studies)
Support CELL ADHESION AND TRANSSYNAPTIC SIGNALING

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWAScat Genome-wide Association Studies This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
CV:Ripke_2013 Genome-wide Association Study Multi-stage GWAS, Sweden population and PGC2. 24 leading SNPs
DMG:Montano_2016 Genome-wide DNA methylation analysis This dataset includes 172 replicated associations between CpGs with schizophrenia. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg22887491 11 131618277 NTM 2.43E-5 0.005 0.067 DMG:Montano_2016


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0005515 protein binding IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0008038 neuron recognition TAS neuron (GO term level: 4) 7891157
GO:0007155 cell adhesion NAS 7891157
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005886 plasma membrane IEA -
GO:0031225 anchored to membrane IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
WILCOX RESPONSE TO PROGESTERONE DN 66 44 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER ADVANCED VS EARLY UP 175 120 All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER UP 443 294 All SZGR 2.0 genes in this pathway
BEGUM目标考评的X3 FOXO1 FUSION DN 45 34 All SZGR 2.0 genes in this pathway
KOYAMA SEMA3B TARGETS DN 411 249 All SZGR 2.0 genes in this pathway
STARK PREFRONTAL CORTEX 22Q11 DELETION UP 195 138 All SZGR 2.0 genes in this pathway
LEE TARGETS OF PTCH1 AND SUFU DN 83 69 All SZGR 2.0 genes in this pathway
IZADPANAH STEM CELL ADIPOSE VS BONE UP 126 92 All SZGR 2.0 genes in this pathway
YAGUE PRETUMOR DRUG RESISTANCE DN 13 11 All SZGR 2.0 genes in this pathway
MIKKELSEN IPS WITH HCP H3K27ME3 102 76 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS UP 221 135 All SZGR 2.0 genes in this pathway
MIKKELSEN ES HCP WITH H3K27ME3 41 30 All SZGR 2.0 genes in this pathway
MIKKELSEN MEF HCP WITH H3K27ME3 590 403 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR DN 36 19 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS DURATION CORR UP 9 7 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP A 898 516 All SZGR 2.0 genes in this pathway
WIEDERSCHAIN TARGETS OF BMI1 AND PCGF2 57 39 All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS UP 163 111 All SZGR 2.0 genes in this pathway
ANASTASSIOU CANCER MESENCHYMAL TRANSITION SIGNATURE 64 40 All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725 838 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-138 882 888 m8 hsa-miR-138brain AGCUGGUGUUGUGAAUC
miR-151 678 685 1A,m8 hsa-miR-151brain ACUAGACUGAAGCUCCUUGAGG
miR-188 629 635 m8 hsa-miR-188 CAUCCCUUGCAUGGUGGAGGGU
miR-28 1177 1183 m8 hsa-miR-28brain AAGGAGCUCACAGUCUAUUGAG
miR-30-5p 789 795 1A hsa-miR-30a-5p UGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrain UGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZ UGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZ UGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5p UGUAAACAUCCUUGACUGGA
miR-346 921 927 1A hsa-miR-346brain UGUCUGCCCGCAUGCCUGCCUCU
miR-361 669 675 m8 hsa-miR-361brain UUAUCAGAAUCUCCAGGGGUAC
miR-369-3p 1017 1023 1A hsa-miR-369-3p AAUAAUACAUGGUUGAUCUUU
miR-374 1017 1023 m8 hsa-miR-374 UUAUAAUACAACCUGAUAAGUG
miR-485-3p 1489 1496 1A,m8 hsa-miR-485-3p GUCAUACACGGCUCUCCUCUCU
miR-495 1048 1054 1A hsa-miR-495brain AAACAAACAUGGUGCACUUCUUU
hsa-miR-495brain AAACAAACAUGGUGCACUUCUUU
miR-504 1080 1086 m8 hsa-miR-504 AGACCCUGGUCUGCACUCUAU
miR-505 1129 1135 m8 hsa-miR-505 GUCAACACUUGCUGGUUUCCUC