| Abstract |
收敛的ph值的证据armacological and animal studies suggests a possible role for the synaptic vesicle glycoprotein 2A gene (SV2A) inschizophreniasusceptibility. To test systematically all common variants in theSV2Agene region for an association withschizophrenia, we used a HapMap-based haplotype tagging approach and tested five SNPs in 794 patients and 843 controls. The SNP rs15931 showed evidence for an association withschizophreniaand was followed-up in an independent sample of 2581 individuals (overall p-value=0.0042, OR=0.779). Our study in the German population provides evidence, at a genetic level, for the involvement of theSV2Agene region inschizophrenia. |