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| 基因id | 象征 | Synonyms | Official Full Name | Location | SZ group? | Functional group? |
|---|---|---|---|---|---|---|
| 56288 | PARD3 | ASIP | Baz | PAR3 | PAR3alpha | PARD-3 | PARD3A | PPP1R118 | SE2-5L16 | SE2-5LT1 | SE2-5T2 | par-3 family cell polarity regulator | 10p11.21 | CV:GWAScat CV：GWASDB CV:PGCnp Expression GO_Annotation PMID:cooccur |
Ascano FMRP targets |
| 5728 | PTEN | 10q23del | BZS | CWS1 | DEC | GLM2 | MHAM | MMAC1 | PTEN1 | TEP1 | phosphatase and tensin homolog | 10q23.3 | CV:PGCnp DMG:Wockner_2014 GO_Annotation Network PMID:cooccur |
COMPOSITESET Darnell FMRP targets |
| 9221 | NOLC1 | NOPP130 | NOPP140 | NS5ATP13 | P130 | 核仁和卷曲体磷蛋白1 | 10q24.32 | CV:PGCnp DMG:Jaffe_2016 |
|
| 5058 | PAK1 | PAKalpha | P21蛋白（CDC42/RAC）激活激酶1 | 11q13.5-q14.1 | CV:PGCnp GO_Annotation Network PMID:cooccur |
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL COMPOSITESET |
| 1027 | CDKN1B | CDKN4 | KIP1 | MEN1B | MEN4 | P27KIP1 | cyclin-dependent kinase inhibitor 1B | 12p13.1-p12 | CV:PGCnp Network PMID:cooccur |
|
| 3479 | IGF1 | IGF-i |Igfi |MGF | 胰岛素像生长因子1 | 12q23.2 | CV:PGCnp GO_Annotation PMID:cooccur |
|
| 8660 | IRS2 | IRS-2 | insulin receptor substrate 2 | 13Q34 | CV:PGCnp GO_Annotation PMID:cooccur |
COMPOSITESET Darnell FMRP targets Ascano FMRP targets |
| 6655 | SOS2 | NS9 | SOS Ras/Rho guanine nucleotide exchange factor 2 | 14Q21 | CV:PGCnp DNM:Gulsuner_2013 |
|
| 207 | AKT1 | AKT | CWS6 | PKB | PKB-ALPHA | PRKBA | RAC | RAC-ALPHA | v-akt小鼠胸腺瘤病毒致癌基因相同器官1 | 14q32.32 | Association 核 CV:PGCnp DMG:vanEijk_2014 DMG:Wockner_2014 DNM：Fromer_2014 gr_cor gr_ng GR_WM Network PMID:cooccur |
G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET |
| 23368 | PPP1R13B | ASPP1 | p53BP2-like | p85 | protein phosphatase 1 regulatory subunit 13B | 14q32.33 | CV:PGCnp DMG:vanEijk_2014 DMG:Wockner_2014 DNM：Ambalavanan_2016 |
|
| 56924 | PAK6 | PAK5 | P21蛋白（CDC42/RAC）激活激酶6 | 15q14 | CV:GWAScat CV:PGC128 CV:PGCnp |
COMPOSITESET Darnell FMRP targets |
| 7249 | TSC2 | LAM | PPP1R160 | TSC4 | tuberous sclerosis 2 | 16p13.3 | CV:PGCnp Network PMID:cooccur |
COMPOSITESET Darnell FMRP targets Ascano FMRP targets |
| 50855 | pard6a | PAR-6A | PAR6 | PAR6C | PAR6alpha | TAX40 | TIP-40 | PAR-6家族细胞极性调节器alpha | 16q22.1 | CV:PGCnp DMG:Wockner_2014 GO_Annotation Network |
|
| 6517 | SLC2A4 | GLUT4 | solute carrier family 2 member 4 | 17p13 | CV:PGCnp | |
| 23533 | PIK3R5 | F730038i15rik |FOAP-2 |P101-PI3K |P101 | phosphoinositide-3-kinase regulatory subunit 5 | 17p13.1 | CV：GWASDB CV:PGCnp |
|
| 7531 | YWHAE | 14-3-3E | HEL2 | KCIP-1 | MDCR | MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon | 17p13.3 | Association CV:PGCnp Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS G2Cdb.human_TAP-PSD-95-CORE G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET Potential synaptic genes |
| 2885 | GRB2 | ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084 | NCKAP2 | growth factor receptor bound protein 2 | 17q24-q25 | CV:PGCnp DMG:Jaffe_2016 Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP Potential synaptic genes |
| 208 | AKT2 | HIHGHH | PKBB | PKBBETA | PRKBB | RAC-BETA | v-akt小鼠胸腺瘤病毒致癌基因相同器官2 | 19q13.1-q13.2 | CV:PGCnp Network PMID:cooccur |
G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP |
| 2931 | GSK3A | - | glycogen synthase kinase 3 alpha | 19q13.2 | CV:PGCnp GO_Annotation Network PMID:cooccur |
|
| 6195 | RPS6KA1 | Hu-1 |mapkapk1a |RSK |RSK1 |p90rsk | ribosomal protein S6 kinase A1 | 1p | CV:PGCnp DMG:Montano_2016 DMG:Nishioka_2013 |
|
| 1647 | GADD45A | DDIT1 | GADD45 | growth arrest and DNA damage inducible alpha | 1p31.2 | CV：GWASDB CV:PGCnp GSMA_IIA |
|
| 998 | CDC42 | CDC42Hs | G25K | TKS | cell division cycle 42 | 1p36.1 | CV：GWASDB CV:PGCnp GO_Annotation Network PMID:cooccur |
STRUCTURAL PLASTICITY |
| 2810 | SFN | 是的 | stratifin | 1p36.11 | CV:PGCnp DMG:Jaffe_2016 PMID:cooccur |
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS COMPOSITESET |
| 5293 | pik3cd | APDS | IMD14 | P110DELTA | PI3K | p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 1p36.2 | CV:PGCnp DMG:Wockner_2014 PMID:cooccur |
|
| 2475 | mtor | FRAP | FRAP1 | FRAP2 | RAFT1 | RAPT1 | SKS | 雷帕霉素的机械靶标 | 1p36.2 | CV:PGCnp DNM：XU_2012 PMID:cooccur |
COMPOSITESET Darnell FMRP targets Ascano FMRP targets |
| 10000 | AKT3 | MPPH | MPPH2 | PKB-GAMMA | PKBG | PRKBG | RAC-PK-gamma | RAC-gamma | STK-2 | v-akt小鼠胸腺瘤病毒致癌基因相同器官3 | 1q44 | CV:GWAScat CV：GWASDB CV:PGC128 CV:PGCnp CV:Ripke_2013 LK：是的 PMID:cooccur |
COMPOSITESET Darnell FMRP targets |
| 57144 | PAK7 | PAK5 | P21蛋白（CDC42/RAC）激活激酶7 | 20p12 | CV:PGCnp DMG:Wockner_2014 GSMA_I PMID:cooccur |
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS |
| 598 | BCL2L1 | BCL-XL/S | BCL2L | BCLX | Bcl-X | PPP1R52 | BCL2 like 1 | 20q11.21 | GO_Annotation Network PMID:cooccur |
|
| 7529 | YWHAB | GW128 | HEL-S-1 | HS1 | KCIP-1 | YWHAA | 酪氨酸3-单加氧酶/色氨酸5-单加氧酶激活蛋白β | 20q13.1 | CV:PGCnp DMG:Wockner_2014 Network |
INTRACELLULAR SIGNAL TRANSDUCTION G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS G2Cdb.human_clathrin G2CDB.HUMAN_MGLUR5 g2cdb.human_synaptosom G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET |
| 5770 | PTPN1 | PTP1B | 蛋白质酪氨酸磷酸酶，非受体1型 | 20q13.1-q13.2 | CV:PGCnp Network PMID:cooccur |
|
| 57580 | PREX1 | P-REX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 20q13.13 | CV:PGCnp DMG:Wockner_2014 |
COMPOSITESET Darnell FMRP targets |
| 7533 | 是的 | YWHA1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta | 22q12.3 | Association CV:PGCnp GO_Annotation gr_ng GR_WM GSMA_I Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS G2CDB.HUMAN_MGLUR5 G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET Potential synaptic genes |
| 10971 | ywhaq | 14-3-3 |1c5 |HS1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta | 2p25.1 | CV:PGCnp DMG:Wockner_2014 Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2CDB.HUMAN_MGLUR5 G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET |
| 5163 | PDK1 | - | pyruvate dehydrogenase kinase 1 | 2 q31.1 | CV:PGCnp DMG:Wockner_2014 PMID:cooccur |
|
| 2066 | ERBB4 | ALS19 | HER4 | p180erbB4 | erb-b2 receptor tyrosine kinase 4 | 2Q33.3-Q34 | Association 核 CV：GWASDB CV:PGCnp DMG:Wockner_2014 GO_Annotation gr_cor gr_ng GR_WM GSMA_IIA GSMA_IIE Network PMID:cooccur |
Potential synaptic genes |
| 1385 | CREB1 | CREB | CREB-1 | cAMP响应元件结合蛋白1 | 2q34 | CV:PGCnp GSMA_IIA GSMA_IIE Network PMID:cooccur |
|
| 3667 | IRS1 | HIRS-1 | insulin receptor substrate 1 | 2q36 | CV:PGCnp DMG:Jaffe_2016 DMG:Montano_2016 DMG:Wockner_2014 DNM：XU_2012 GSMA_IIA GSMA_IIE Network PMID:cooccur |
G2CDB.HUMANNRC G2Cdb.humanPSP COMPOSITESET Ascano FMRP targets |
| 2932 | GSK3B | - | glycogen synthase kinase 3 beta | 3q13.3 | Association CV:PGCnp GO_Annotation gr_cor GR_WM Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET Darnell FMRP targets Potential synaptic genes |
| 5290 | PIK3CA | CLOVE | CWS5 | MCAP | MCM | MCMTC | PI3K | p110-alpha | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 3Q26.3 | CV:PGCnp Network PMID:cooccur |
G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP Potential synaptic genes |
| 5062 | PAK2 | PAK65 | PAKgamma | P21蛋白（CDC42/RAC）激活激酶2 | 3q29 | CNV:YES CV:PGCnp DMG:Wockner_2014 Network PMID:cooccur |
|
| 2549 | GAB1 | - | GRB2 associated binding protein 1 | 4q31.21 | CV:PGCnp | |
| 2309 | FOXO3 | AF6q21 | FKHRL1 | FKHRL1P2 | FOXO2 | FOXO3A | forkhead box O3 | 6q21 | CV:PGCnp DMG:Wockner_2014 Network |
COMPOSITESET Darnell FMRP targets |
| 6196 | RPS6KA2 | HU-2 | MAPKAPK1C | RSK | RSK3 | S6K-alpha | S6K-alpha2 | p90-RSK3 | p90RSK2 | pp90RSK3 | ribosomal protein S6 kinase A2 | 6q27 | CV：GWASDB CV:PGCnp DMG:Wockner_2014 Network |
|
| 9586 | CREB5 | CRE-BPA | CREB-5 | cAMP响应元件结合蛋白5 | 7p15.1 | CV:PGCnp DEG：Zhao_2015 |
|
| 9265 | Cyth3 | ARNO3 | GRP1 | PSCD3 | cytohesin 3 | 7p22.1 | CV:PGCnp DMG:Wockner_2014 |
Ascano FMRP targets Potential synaptic genes |
| 7532 | 是的 | 14-3-3GAMMA | PPP1R170 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | 7q11.23 | CV:PGCnp DMG:Jaffe_2016 GO_Annotation Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS G2CDB.HUMAN_MGLUR5 G2Cdb.human_mitochondria G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET Darnell FMRP targets |
| 7534 | ywhaz | 14-3-3-zeta | HEL-S-3 | HEL-S-93 | HEL4 | KCIP-1 | YWHAD | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | 8Q23.1 | Association CV:PGCnp DMG:Wockner_2014 DNM：Fromer_2014 Network PMID:cooccur |
INTRACELLULAR SIGNAL TRANSDUCTION G2CDB.HUMAN_MGLUR5 G2Cdb.human_mitochondria G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP COMPOSITESET Potential synaptic genes |
| 4609 | MYC | MRTL | MYCC | bHLHe39 | c-Myc | v-myc avian myelocytomatosis viral oncogene homolog | 8Q24.21 | CV:PGCnp DMG:Jaffe_2016 Expression Network PMID:cooccur |
|
| 5747 | PTK2 | FADK | FAK | FAK1 | FRNK | PPP1R71 | p125FAK | pp125FAK | 蛋白酪氨酸激酶2 | 8Q24.3 | CV:PGCnp DMG:Wockner_2014 GO_Annotation Network PMID:cooccur |
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL COMPOSITESET Darnell FMRP targets |
| 10488 | CREB3 | LUMAN | LZIP | sLZIP | cAMP响应元件结合蛋白3 | 9p13.3 | DMG:Nishioka_2013 | |
| 1029 | CDKN2A | ARF | CDK4I | CDKN2 | CMM2 | INK4 | INK4A | MLM | MTS-1 | MTS1 | P14 | P14ARF | P16 | P16-INK4A | P16INK4 | P16INK4A | P19 | P19ARF | TP16 | cyclin-dependent kinase inhibitor 2A | 9p21 | CV:PGCnp DMG:Nishioka_2013 Network |
|
| 10682 | EBP | CDPX2 | CHO2 | CPX | CPXD | MEND | emopamil binding protein (sterol isomerase) | Xp11.23-p11.22 | CV:PGCnp PMID:cooccur |
|
| 6197 | RPS6KA3 | CLS | HU-3 | ISPK-1 | MAPKAPK1B | MRX19 | RSK | RSK2 | S6K-alpha3 | p90-RSK2 | pp90RSK2 | ribosomal protein S6 kinase A3 | XP22.2-P22.1 | CV:GWAScat CV:PGC128 CV:PGCnp Expression GO_Annotation Network |
G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP Potential synaptic genes |
| 5063 | PAK3 | MRX30 | MRX47 | OPHN3 | PAK-3 | PAK3beta | bPAK | beta-PAK | P21蛋白（CDC42/RAC）激活激酶3 | Xq23 | CV:PGCnp PMID:cooccur |
Potential synaptic genes |