肺动脉高血压知识库(bioinfom_tsdb)
bioinfom_tsdb
肺动脉高血压知识库
一般信息|文学|表达式|监管|变体|交互

基本信息

基因身份证

126520年

的名字

PLK5

同义的

polo-like激酶5;PLK5 polo-like激酶5

定义

不活跃的丝氨酸/ threonine-protein激酶PLK5 | polo-like激酶5,假基因

位置

19 p13.3

基因型

蛋白质编码

突变简介:

 域的突变
在17个主要癌症突变模式
LoF vs错义突变
数据库V72宇宙的所有拷贝数变化
宇宙的所有突变数据库V72

突变总结蛋白质域

前
我们使用从合奏BioMart uniprot蛋白质结构数据的数据库。圆的大小显示了相对变异数。

非同义(上)和(底部)同义突变比例对各种癌症

前
非同义突变模式在17个主要的癌症类型。
同义突变模式在17个主要的癌症类型。

损失函数的突变与错义突变

前
损失函数的突变比较错义突变。
丧失突变在错义突变的比例是0.00。

各种癌症的拷贝数变化

前
拷贝数变化的17个主要癌症组:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

拷贝数变化的17个主要的癌症类型:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

宇宙体细胞突变(最高)

突变(cd;AA;科)

网站

组织学

突变类型

c.508C > T;p.R170W;19:1529764 - 1529764

 胰腺 癌 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.967G > C;p.G323R;19:1535206 - 1535206

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.956_958delCCC;p.P320delP;19:1535195 - 1535197

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 删除——在坐标系

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 甲状腺 其他;肿瘤 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 肝 癌;hepatocellular_carcinoma 替换-错义

c.941G >;p.R314Q;19:1535180 - 1535180

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.703A > C;p.T235P;19:1531872 - 1531872

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.339G > T;p.T113T;19:1528908 - 1528908

 甲状腺 其他;肿瘤 替换-编码沉默

c.319C > T;p.R107W;19:1528419 - 1528419

 biliary_tract;胆囊 癌;腺癌 替换-错义

c.709C > T;p.R237W;19:1531878 - 1531878

 肺 癌;squamous_cell_carcinoma 替换-错义

c.701C > T;p.A234V;19:1531870 - 1531870

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.701C > T;p.A234V;19:1531870 - 1531870

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.701C > T;p.A234V;19:1531870 - 1531870

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.673C > T;p.R225C;19:1531842 - 1531842

 前列腺癌 癌;腺癌 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.757C > G;p.L253V;19:1533973 - 1533973

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.984C > T;p.H328H;19:1535223 - 1535223

 肺 癌;squamous_cell_carcinoma 替换-编码沉默

c.261A > C;p.I87I;19:1528361 - 1528361

 甲状腺 其他;肿瘤 替换-编码沉默

c.38C >;p.A13D;19:1527971 - 1527971

 upper_aerodigestive_tract;口 癌;squamous_cell_carcinoma 替换-错义

c.38C >;p.A13D;19:1527971 - 1527971

 upper_aerodigestive_tract;口 癌 替换-错义

c.905G > T;p.G302V;19:1535144 - 1535144

 胰腺 癌 替换-错义

c.846G >;p.P282P;19:1535085 - 1535085

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-编码沉默

c.846G >;p.P282P;19:1535085 - 1535085

 乳房 癌 替换-编码沉默

c.255C > T;p.F85F;19:1528355 - 1528355

 胰腺 癌 替换-编码沉默

c.266C > T;p.P89L;19:1528366 - 1528366

 upper_aerodigestive_tract;head_neck 癌;squamous_cell_carcinoma 替换-错义

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