| 一般信息|文学|表达式|监管|变体|交互 |
基本信息 |
|
|---|---|
基因身份证 |
26260年 |
的名字 |
FBXO25 |
同义的 |
盒蛋白质25;FBXO25盒蛋白质25 |
定义 |
盒只有蛋白质25 | Fbx25盒蛋白质 |
位置 |
8 p23.3 |
基因型 |
蛋白质编码 |
突变简介: |
域的突变 在17个主要癌症突变模式 LoF vs错义突变 数据库V72宇宙的所有拷贝数变化 宇宙的所有突变数据库V72 |
突变总结蛋白质域 |
前 |
 |
非同义(上)和(底部)同义突变比例对各种癌症 |
前 |
 |
 |
损失函数的突变与错义突变 |
前 |
 |
| 丧失突变在错义突变的比例是0.14。 |
各种癌症的拷贝数变化 |
前 |
 |
拷贝数变化的17个主要的癌症类型:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
宇宙体细胞突变(最高) |
|||
突变(cd;AA;科) |
网站 |
组织学 |
突变类型 |
|---|---|---|---|
c.465C > T;p.I155I;8:450073 - 450073 |
皮肤 | malignant_melanoma | 替换-编码沉默 |
c.507C > G;p.I169M;8:451300 - 451300 |
肺 | 癌;squamous_cell_carcinoma | 替换-错义 |
c.357C >;p.I119I;8:435683 - 435683 |
乳房 | 癌 | 替换-编码沉默 |
c.961C > T;p.R321W;8:463124 - 463124 |
乳房 | 癌 | 替换-错义 |
c.735C > T;p.D245D;8:458443 - 458443 |
large_intestine;结肠 | 癌;腺癌 | 替换-编码沉默 |
c.547C > T;p.L183F;8:451340 - 451340 |
皮肤;head_neck | 癌;squamous_cell_carcinoma | 替换-错义 |
c.1040C >;p.A347D;8:468740 - 468740 |
卵巢 | 癌;serous_carcinoma | 替换-错义 |
c.121_122delAT;p.I41fs * 8;8:413200 - 413201 |
胰腺 | 癌;腺癌 | 删除——转移 |
c.338C > G;p.S113 *;8:435664 - 435664 |
urinary_tract;膀胱 | 癌 | 替换-胡说 |
c.570T > C;p.S190S;8:451363 - 451363 |
large_intestine;直肠 | 癌;腺癌 | 替换-编码沉默 |
c.138C > G;p.I46M;8:431344 - 431344 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.138C > G;p.I46M;8:431344 - 431344 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm;acute_myeloid_leukaemia | 替换-错义 |
c.497C >;p.P166H;8:451290 - 451290 |
子宫内膜 | 癌;endometrioid_carcinoma | 替换-错义 |
c.469C > G;p.Q157E;8:450077 - 450077 |
子宫颈 | 癌;squamous_cell_carcinoma | 替换-错义 |
c.657T >;p.T219T;8:451450 - 451450 |
前列腺癌 | 癌 | 替换-编码沉默 |
c.1031G >;p.C344Y;8:468731 - 468731 |
胃 | 癌;腺癌 | 替换-错义 |
c.357C > T;p.I119I;8:435683 - 435683 |
皮肤 | malignant_melanoma | 替换-编码沉默 |
c.892T > G;p.L298V;8:463055 - 463055 |
肝 | 癌 | 替换-错义 |
c.624C > T;p.A208A;8:451417 - 451417 |
胃 | 癌;腺癌 | 替换-编码沉默 |
c.568T > C;p.S190P;8:451361 - 451361 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.438G > T;p.K146N;8:450046 - 450046 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.616A > G;p.I206V;8:451409 - 451409 |
乳房 | 癌 | 替换-错义 |
c.939C > T;p.Y313Y;8:463102 - 463102 |
胃 | 癌;腺癌 | 替换-编码沉默 |
c.426C > T;p.G142G;8:450034 - 450034 |
胃 | 癌;腺癌 | 替换-编码沉默 |
c.1060A > G;p.T354A;8:468760 - 468760 |
肝 | 癌 | 替换-错义 |
c.597G >;p.W199 *;8:451390 - 451390 |
皮肤;head_neck | 癌;squamous_cell_carcinoma | 替换-胡说 |
c.15T > C;p.G5G;8:413094 - 413094 |
食道;lower_third | 癌;腺癌 | 替换-编码沉默 |
c.239-1G > T;p。?。8:432885 - 432885 |
large_intestine;直肠 | 癌;腺癌 | 未知的 |
c.603C > T;p.C201C;8:451396 - 451396 |
肾脏 | 癌;clear_cell_renal_cell_carcinoma | 替换-编码沉默 |
c.427G >;p.V143M;8:450035 - 450035 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.988G > T;p.D330Y;8:467720 - 467720 |
乳房 | 癌 | 替换-错义 |
c.193delA;p.R67fs * 44;8:431399 - 431399 |
large_intestine;盲肠 | 癌;腺癌 | 删除——转移 |
c.604C > T;p.R202 *;8:451397 - 451397 |
子宫内膜 | 癌;endometrioid_carcinoma | 替换-胡说 |
c.193delA;p.R67fs * 44;8:431399 - 431399 |
large_intestine;结肠 | 癌;腺癌 | 删除——转移 |
c.315A > G;p.E105E;8:435641 - 435641 |
子宫内膜 | 癌;endometrioid_carcinoma | 替换-编码沉默 |
c.570T >;p.S190S;8:451363 - 451363 |
肺 | 癌;non_small_cell_carcinoma | 替换-编码沉默 |
c.1072C >;p.P358T;8:468772 - 468772 |
adrenal_gland;adrenal_gland | adrenal_cortical_carcinoma;功能 | 替换-错义 |
c.1072C > T;p.P358S;8:468772 - 468772 |
食管 | 癌;腺癌 | 替换-错义 |
c.470delA;p.K158fs * 11;8:450078 - 450078 |
large_intestine;结肠 | 癌;腺癌 | 删除——转移 |
c.399delA;p.K134fs * 4;8:450007 - 450007 |
large_intestine | 癌;腺癌 | 删除——转移 |
c.399delA;p.K134fs * 4;8:450007 - 450007 |
large_intestine | 癌;腺癌 | 删除——转移 |
c.1015-2A > G;p。?。8:468713 - 468713 |
食道;lower_third | 癌;squamous_cell_carcinoma | 未知的 |
c.784C > T;p.L262F;8:458492 - 458492 |
haematopoietic_and_lymphoid_tissue;central_nervous_system | lymphoid_neoplasm;primary_central_nervous_system_lymphoma | 替换-错义 |
c.833C >;p.A278D;8:458541 - 458541 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.533C > T;p.S178F;8:451326 - 451326 |
皮肤;head_neck | 癌;squamous_cell_carcinoma | 替换-错义 |
c.113G >;p.R38H;8:413192 - 413192 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.1087G >;p.D363N;8:468787 - 468787 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.113G >;p.R38H;8:413192 - 413192 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm;acute_myeloid_leukaemia | 替换-错义 |
c.349C > T;p.Q117 *;8:435675 - 435675 |
皮肤;head_neck | 癌;squamous_cell_carcinoma | 替换-胡说 |
c.436A > C;p.K146Q;8:450044 - 450044 |
食道;lower_third | 癌;腺癌 | 替换-错义 |
c.517C > G;p.L173V;8:451310 - 451310 |
肺 | 癌;腺癌 | 替换-错义 |
c.75T > C;p.C25C;8:413154 - 413154 |
子宫内膜 | 癌;endometrioid_carcinoma | 替换-编码沉默 |