肺动脉高血压知识库(bioinfom_tsdb)
bioinfom_tsdb
肺动脉高血压知识库
一般信息|文学|表达式|监管|变体|交互

基本信息

基因身份证

3627年

的名字

CXCL10

同义的

趋化因子(C-X-C主题)配体10;CXCL10;趋化因子配体(C-X-C主题)10

定义

10 kDa射线诱发干扰素蛋白| C-X-C主题趋化因子10 |γIP10 | gamma-IP10 | interferon-inducible细胞因子IP-10 |从全身的干扰素(γ)细胞株蛋白质10 |小诱导细胞因子B亚科(Cys-X-Cys)成员10 | small-inducible cyt

位置

4温度系数

基因型

蛋白质编码

突变简介:

 域的突变
在17个主要癌症突变模式
LoF vs错义突变
数据库V72宇宙的所有拷贝数变化
宇宙的所有突变数据库V72

突变总结蛋白质域

前
我们使用从合奏BioMart uniprot蛋白质结构数据的数据库。圆的大小显示了相对变异数。

非同义(上)和(底部)同义突变比例对各种癌症

前
非同义突变模式在17个主要的癌症类型。
同义突变模式在17个主要的癌症类型。

损失函数的突变与错义突变

前
损失函数的突变比较错义突变。
丧失突变在错义突变的比例是0.00。

各种癌症的拷贝数变化

前
拷贝数变化的17个主要癌症组:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; NS, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

拷贝数变化的17个主要的癌症类型:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract

宇宙体细胞突变(最高)

突变(cd;AA;科)

网站

组织学

突变类型

c.249G > T;p.K83N;4:76022395 - 76022395

 子宫内膜 癌;endometrioid_carcinoma 替换-错义

c.249G > T;p.K83N;4:76022395 - 76022395

 large_intestine;盲肠 癌;腺癌 替换-错义

c.138A > G;p.E46E;4:76022741 - 76022741

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-编码沉默

c.223C > T;p.L75L;4:76022421 - 76022421

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-编码沉默

c.100A > G;p.S34G;4:76022779 - 76022779

 皮肤 malignant_melanoma 替换-错义

c.114A > G;p.Q38Q;4:76022765 - 76022765

 皮肤 malignant_melanoma 替换-编码沉默

c.108T > C;p.S36S;4:76022771 - 76022771

 肾脏 癌;clear_cell_renal_cell_carcinoma 替换-编码沉默

c.82G >;p.V28I;4:76022797 - 76022797

 乳房 癌 替换-错义

c.279G >;p.R93R;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-编码沉默

c.279G >;p.R93R;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-编码沉默

c.279G >;p.R93R;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-编码沉默

c.279G >;p.R93R;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-编码沉默

c.279G >;p.R93R;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-编码沉默

c.237G >;p.S79S;4:76022407 - 76022407

 肺 癌;squamous_cell_carcinoma 替换-编码沉默

c.273G >;p.K91K;4:76022371 - 76022371

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-编码沉默

c.22A > G;p.I8V;4:76023410 - 76023410

 子宫内膜 癌;endometrioid_carcinoma 替换-错义

c.23T > C;p.I8T;4:76023409 - 76023409

 large_intestine 癌;腺癌 替换-错义

c.178G >;p.V60I;4:76022701 - 76022701

 胃 癌;腺癌 替换-错义

c.236C > T;p.S79L;4:76022408 - 76022408

 large_intestine;盲肠 癌;腺癌 替换-错义

c.42G >;p.L14L;4:76023390 - 76023390

 胃 癌;腺癌 替换-编码沉默

c.236C > T;p.S79L;4:76022408 - 76022408

 皮肤 malignant_melanoma 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.279G > T;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

c.292C > T;p.P98S;4:76021935 - 76021935

 皮肤 malignant_melanoma 替换-错义

c.275A > T;p.E92V;4:76022369 - 76022369

 large_intestine;直肠 癌;腺癌 替换-错义

c.69T >;p.P23P;4:76022810 - 76022810

 胰腺 癌 替换-编码沉默

c.61G >;p.G21R;4:76023371 - 76023371

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.279G > C;p.R93S;4:76021948 - 76021948

 haematopoietic_and_lymphoid_tissue haematopoietic_neoplasm;acute_myeloid_leukaemia 替换-错义

”)
Baidu