| 一般信息|文学|表达式|监管|变体|交互 |
基本信息 |
|
|---|---|
基因身份证 |
56475年 |
的名字 |
RPRM |
同义的 |
reprimo, TP53依赖G2逮捕中介候选人;RPRM; reprimo, TP53依赖G2逮捕中介的候选人 |
定义 |
候选人中介的p53依赖G2逮捕|候选人中介的p53-dependent G2逮捕|蛋白质reprimo | reprimo, TP53依赖G2逮捕中介的候选人 |
位置 |
2 q23.3 |
基因型 |
蛋白质编码 |
突变简介: |
域的突变 在17个主要癌症突变模式 LoF vs错义突变 数据库V72宇宙的所有拷贝数变化 宇宙的所有突变数据库V72 |
突变总结蛋白质域 |
前 |
 |
非同义(上)和(底部)同义突变比例对各种癌症 |
前 |
 |
 |
损失函数的突变与错义突变 |
前 |
 |
| 丧失突变在错义突变的比例是0.00。 |
各种癌症的拷贝数变化 |
前 |
 |
拷贝数变化的17个主要的癌症类型:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
宇宙体细胞突变(最高) |
|||
突变(cd;AA;科) |
网站 |
组织学 |
突变类型 |
|---|---|---|---|
c.182T > C;p.V61A;2:153478384 - 153478384 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.238C > G;p.L80V;2:153478328 - 153478328 |
乳房 | 癌 | 替换-错义 |
c.310G >;p.V104M;2:153478256 - 153478256 |
central_nervous_system;大脑 | 神经胶质瘤;astrocytoma_Grade_IV | 替换-错义 |
c.310G >;p.V104M;2:153478256 - 153478256 |
central_nervous_system;大脑 | 神经胶质瘤;astrocytoma_Grade_IV | 替换-错义 |
c.81G >;p.V27V;2:153478485 - 153478485 |
肾脏 | 癌;papillary_renal_cell_carcinoma | 替换-编码沉默 |
c.85T > C;p.C29R;2:153478481 - 153478481 |
胃 | 癌;腺癌 | 替换-错义 |
c.43T > G;p.F15V;2:153478523 - 153478523 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm;acute_myeloid_leukaemia | 替换-错义 |
c.238C > T;p.L80L;2:153478328 - 153478328 |
胃 | 癌;腺癌 | 替换-编码沉默 |
c.180G >;p.A60A;2:153478386 - 153478386 |
large_intestine;结肠 | 癌;腺癌 | 替换-编码沉默 |
c.74G >;p.R25Q;2:153478492 - 153478492 |
皮肤 | malignant_melanoma | 替换-错义 |
c.16G >;p.G6S;2:153478550 - 153478550 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.137C >;p.P46Q;2:153478429 - 153478429 |
肺 | 癌;squamous_cell_carcinoma | 替换-错义 |
c.287G >;p.R96K;2:153478279 - 153478279 |
食管 | 癌;腺癌 | 替换-错义 |
c.203C > T;p.T68I;2:153478363 - 153478363 |
胃 | 癌;腺癌 | 替换-错义 |
c.99G >;p.A33A;2:153478467 - 153478467 |
食管 | 癌;腺癌 | 替换-编码沉默 |
c.139G >;p.D47N;2:153478427 - 153478427 |
前列腺癌 | 癌 | 替换-错义 |
c.228C > T;p.L76L;2:153478338 - 153478338 |
large_intestine;结肠 | 癌;腺癌 | 替换-编码沉默 |
c.274G >;p.V92M;2:153478292 - 153478292 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.137C > T;p.P46L;2:153478429 - 153478429 |
胃 | 癌;腺癌 | 替换-错义 |
c.190G >;p.V64M;2:153478376 - 153478376 |
胃 | 癌;腺癌 | 替换-错义 |
c.167T > G;p.V56G;2:153478399 - 153478399 |
骨;胫骨 | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 替换-错义 |
c.79G >;p.V27M;2:153478487 - 153478487 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.124G >;p.A42T;2:153478442 - 153478442 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.291G >;p.P97P;2:153478275 - 153478275 |
large_intestine;结肠 | 癌;腺癌 | 替换-编码沉默 |
c.102C > T;p.S34S;2:153478464 - 153478464 |
large_intestine;结肠 | 癌;腺癌 | 替换-编码沉默 |
c.291G >;p.P97P;2:153478275 - 153478275 |
large_intestine | 癌;腺癌 | 替换-编码沉默 |
c.39C >;p.G13G;2:153478527 - 153478527 |
肺;right_lower_lobe | 癌;腺癌 | 替换-编码沉默 |
c.61G >;p.E21K;2:153478505 - 153478505 |
胃 | 癌;腺癌 | 替换-错义 |
c.131G >;p.G44E;2:153478435 - 153478435 |
皮肤 | malignant_melanoma | 替换-错义 |
c.287G > T;p.R96M;2:153478279 - 153478279 |
large_intestine;结肠 | 癌 | 替换-错义 |
c.164G >;p.R55H;2:153478402 - 153478402 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.192G > C;p.V64V;2:153478374 - 153478374 |
large_intestine | 癌;腺癌 | 替换-编码沉默 |
c.192G > C;p.V64V;2:153478374 - 153478374 |
large_intestine | 癌;腺癌 | 替换-编码沉默 |
c.27G > T;p.T9T;2:153478539 - 153478539 |
肺 | 癌;腺癌 | 替换-编码沉默 |
c.319G >;p.G107R;2:153478247 - 153478247 |
皮肤 | malignant_melanoma | 替换-错义 |
c.138G >;p.P46P;2:153478428 - 153478428 |
large_intestine;结肠 | 癌;腺癌 | 替换-编码沉默 |