| 一般信息|文学|表达式|监管|变体|交互 |
基本信息 |
|
|---|---|
基因身份证 |
7447年 |
的名字 |
VSNL1 |
同义的 |
visinin-like 1; VSNL1; visinin-like 1 |
定义 |
VLP-1 | 3 | hippocalcin-like蛋白质visinin-like蛋白质1 |
位置 |
2 p24.3 |
基因型 |
蛋白质编码 |
突变简介: |
域的突变 在17个主要癌症突变模式 LoF vs错义突变 数据库V72宇宙的所有拷贝数变化 宇宙的所有突变数据库V72 |
突变总结蛋白质域 |
前 |
 |
非同义(上)和(底部)同义突变比例对各种癌症 |
前 |
 |
 |
损失函数的突变与错义突变 |
前 |
 |
| 丧失突变在错义突变的比例是0.18。 |
各种癌症的拷贝数变化 |
前 |
 |
拷贝数变化的17个主要的癌症类型:1;乳腺癌、2;中枢神经系统,3;子宫颈,4;子宫内膜,5;lymphoid_tissue造血,6;肾脏,7;大肠,8;肝脏,9;肺癌、10; Not specific, 11; Ovary, 12; Pancreas, 13; Prostate, 14; Skin, 15; Stomach, 16; Thyroid, 17; Urinary tract |
宇宙体细胞突变(最高) |
|||
突变(cd;AA;科) |
网站 |
组织学 |
突变类型 |
|---|---|---|---|
c.61G > T;p.E21 *;2:17592135 - 17592135 |
肺 | 癌;squamous_cell_carcinoma | 替换-胡说 |
c.129A > G;p.L43L;2:17592203 - 17592203 |
肾脏 | 癌;clear_cell_renal_cell_carcinoma | 替换-编码沉默 |
c.340G >;p.G114S;2:17649587 - 17649587 |
胃 | 癌;腺癌 | 替换-错义 |
c.5G > T;p.G2V;2:17592079 - 17592079 |
胃 | 癌;腺癌 | 替换-错义 |
c.134T > C;p.L45P;2:17592208 - 17592208 |
皮肤 | malignant_melanoma | 替换-错义 |
c.531C >;p.S177R;2:17655349 - 17655349 |
肺 | 癌;腺癌 | 替换-错义 |
c.195C >;p.A65A;2:17649442 - 17649442 |
肺 | 癌;腺癌 | 替换-编码沉默 |
c.271A > C;p.I91L;2:17649518 - 17649518 |
large_intestine;直肠 | 癌;腺癌 | 替换-错义 |
c.136G >;p.E46K;2:17592210 - 17592210 |
皮肤 | malignant_melanoma | 替换-错义 |
c.413T > G;p.M138R;2:17655231 - 17655231 |
乳房 | 癌 | 替换-错义 |
c.411G > T;p.M137I;2:17655229 - 17655229 |
肺 | 癌;small_cell_carcinoma | 替换-错义 |
c.145C > T;p.Q49 *;2:17592219 - 17592219 |
皮肤 | malignant_melanoma | 替换-胡说 |
c.97_98GG > AA;p.G33K;2:17592171 - 17592172 |
皮肤 | malignant_melanoma | 替换-错义 |
c.25G > T;p.A9S;2:17592099 - 17592099 |
肺 | 癌;squamous_cell_carcinoma | 替换-错义 |
c.140A > T;p.E47V;2:17592214 - 17592214 |
皮肤 | malignant_melanoma | 替换-错义 |
c.42G > T;p.E14D;2:17592116 - 17592116 |
卵巢 | 癌;serous_carcinoma | 替换-错义 |
c.438G >;p.T146T;2:17655256 - 17655256 |
large_intestine | 癌;腺癌 | 替换-编码沉默 |
c.98G >;p.G33E;2:17592172 - 17592172 |
皮肤;树干 | malignant_melanoma | 替换-错义 |
c.24delG;p.A9fs * 4;2:17592098 - 17592098 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm;chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 删除——转移 |
c.41A > G;p.E14G;2:17592115 - 17592115 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.41A > G;p.E14G;2:17592115 - 17592115 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.97G >;p.G33R;2:17592171 - 17592171 |
皮肤;粘膜 | malignant_melanoma | 替换-错义 |
c.218A > G;p.D73G;2:17649465 - 17649465 |
食道;lower_third | 癌;腺癌 | 替换-错义 |
c.550C >;p.L184I;2:17655368 - 17655368 |
子宫内膜 | 癌;endometrioid_carcinoma | 替换-错义 |
c.169C > T;p.P57S;2:17649416 - 17649416 |
皮肤;粘膜 | malignant_melanoma | 替换-错义 |
c.135C > T;p.L45L;2:17592209 - 17592209 |
皮肤 | malignant_melanoma | 替换-编码沉默 |
c.103C >;p.L35I;2:17592177 - 17592177 |
子宫内膜 | 癌;endometrioid_carcinoma | 替换-错义 |
c.263C > T;p.A88V;2:17649510 - 17649510 |
large_intestine;结肠 | 癌;腺癌 | 替换-错义 |
c.136G > C;p.E46Q;2:17592210 - 17592210 |
urinary_tract;膀胱 | 癌 | 替换-错义 |
c.208C > T;p.R70 *;2:17649455 - 17649455 |
胰腺 | 癌 | 替换-胡说 |
c.176G >;p.G59E;2:17649423 - 17649423 |
皮肤;head_neck | 癌;squamous_cell_carcinoma | 替换-错义 |
c.490G >;p.D164N;2:17655308 - 17655308 |
肺 | 癌;腺癌 | 替换-错义 |
c.448C > G;p.R150G;2:17655266 - 17655266 |
肺;right_upper_lobe | 癌;腺癌 | 替换-错义 |
c.348C > T;p.I116I;2:17649595 - 17649595 |
食道;lower_third | 癌;腺癌 | 替换-编码沉默 |
c.89G > T;p.W30L;2:17592163 - 17592163 |
肺 | 癌;腺癌 | 替换-错义 |
c.493C > G;p.Q165E;2:17655311 - 17655311 |
乳房 | 癌 | 替换-错义 |
c.175G >;p.G59R;2:17649422 - 17649422 |
皮肤 | malignant_melanoma | 替换-错义 |
c.357G > T;p.V119V;2:17649604 - 17649604 |
large_intestine | 癌;腺癌 | 替换-编码沉默 |
c.138G >;p.E46E;2:17592212 - 17592212 |
皮肤 | malignant_melanoma | 替换-编码沉默 |