肺动脉高血压知识库(bioinfom_tsdb)
bioinfom_tsdb
肺动脉高血压知识库
一般信息|文学|表达式|监管|变体|交互

基本信息

基因身份证

89870年

的名字

TRIM15

同义的

三方主题包含15;TRIM15;三方主题包含15

定义

无名指蛋白质93 |三方motif-containing 15 |三方motif-containing 15 | 178 |锌指蛋白锌指蛋白B7

位置

6 . 3

基因型

蛋白质编码

突变简介:

 域的突变
在17个主要癌症突变模式
LoF vs错义突变
数据库V72宇宙的所有拷贝数变化
宇宙的所有突变数据库V72

突变总结蛋白质域

前
我们使用从合奏BioMart uniprot蛋白质结构数据的数据库。圆的大小显示了相对变异数。

非同义(上)和(底部)同义突变比例对各种癌症

前
非同义突变模式在17个主要的癌症类型。
同义突变模式在17个主要的癌症类型。

损失函数的突变与错义突变

前
损失函数的突变比较错义突变。
丧失突变在错义突变的比例是0.07。

各种癌症的拷贝数变化

前

没有TRIM15记录

宇宙体细胞突变(最高)

突变(cd;AA;科)

网站

组织学

突变类型

c.135G > C;p.Q45H;6:30163819 - 30163819

 肺 癌;squamous_cell_carcinoma 替换-错义

c.221C > T;p.P74L;6:30163905 - 30163905

 皮肤 malignant_melanoma 替换-错义

c.791T > C;p.I264T;6:30170560 - 30170560

 central_nervous_system;大脑 神经胶质瘤 替换-错义

c.4C > T;p.P2S;6:30163688 - 30163688

 肺 癌;squamous_cell_carcinoma 替换-错义

c.1263C > T;p.Y421Y;6:30172214 - 30172214

 胃 癌;腺癌 替换-编码沉默

c.270C > T;p.I90I;6:30163954 - 30163954

 乳房 癌 替换-编码沉默

c.1037C > G;p.S346C;6:30171988 - 30171988

 urinary_tract;膀胱 癌 替换-错义

c.971G >;p.S324N;6:30171922 - 30171922

 large_intestine;结肠 癌;腺癌 替换-错义

c.463C > T;p.L155F;6:30167257 - 30167257

 皮肤 malignant_melanoma 替换-错义

c.856G > C;p.A286P;6:30170984 - 30170984

 large_intestine;结肠 癌;腺癌 替换-错义

c.859C >;p.H287N;6:30170987 - 30170987

 食管 癌;腺癌 替换-错义

c.777C > T;p.D259D;6:30170546 - 30170546

 large_intestine;结肠 癌;腺癌 替换-编码沉默

c.234G > T;p.L78L;6:30163918 - 30163918

 肺 癌;squamous_cell_carcinoma 替换-编码沉默

c.273_275delCTT;p.F93delF;6:30163957 - 30163959

 large_intestine;结肠 癌;腺癌 删除——在坐标系

c.128T > G;p.L43R;6:30163812 - 30163812

 肝 癌 替换-错义

c.128T > G;p.L43R;6:30163812 - 30163812

 肝 癌;hepatocellular_carcinoma 替换-错义

c.233T > C;p.L78P;6:30163917 - 30163917

 肺 癌;squamous_cell_carcinoma 替换-错义

c.907G >;p.A303T;6:30171858 - 30171858

 large_intestine;盲肠 癌;腺癌 替换-错义

c.535G >;p.E179K;6:30168357 - 30168357

 皮肤 malignant_melanoma 替换-错义

c.576G >;p.R192R;6:30168398 - 30168398

 皮肤 malignant_melanoma 替换-编码沉默

c.1335C > T;p.S445S;6:30172286 - 30172286

 urinary_tract;膀胱 癌 替换-编码沉默

c.138G >;p.M46I;6:30163822 - 30163822

 皮肤 malignant_melanoma 替换-错义

c.410T > C;p.L137P;6:30167204 - 30167204

 central_nervous_system;大脑 神经胶质瘤 替换-错义

c.451G >;p.E151K;6:30167245 - 30167245

 肺 癌;腺癌 替换-错义

c.1360G >;p.V454I;6:30172311 - 30172311

 食管 癌;腺癌 替换-错义

c.663G >;p.K221K;6:30168485 - 30168485

 皮肤 malignant_melanoma 替换-编码沉默

c.749T > C;p.F250S;6:30170518 - 30170518

 central_nervous_system;大脑 神经胶质瘤 替换-错义

c.420G >;p.E140E;6:30167214 - 30167214

 胰腺 癌 替换-编码沉默

c.415A > C;p.T139P;6:30167209 - 30167209

 皮肤 malignant_melanoma 替换-错义

c.436G >;p.D146N;6:30167230 - 30167230

 皮肤 malignant_melanoma 替换-错义

c.770C >;p.S257Y;6:30170539 - 30170539

 子宫内膜 癌;endometrioid_carcinoma 替换-错义

c.436G >;p.D146N;6:30167230 - 30167230

 皮肤 malignant_melanoma 替换-错义

c.437delA;p.D146fs * 2;6:30167231 - 30167231

 肝 癌 删除——转移

c.709G >;p.D237N;6:30169241 - 30169241

 皮肤 malignant_melanoma 替换-错义

c.621A > T;p.T207T;6:30168443 - 30168443

 肝 癌 替换-编码沉默

c.913C > T;p.R305W;6:30171864 - 30171864

 large_intestine 癌;腺癌 替换-错义

c.294C >;p.A98A;6:30163978 - 30163978

 肺 癌;squamous_cell_carcinoma 替换-编码沉默

c.263_265delAGA;p.K89delK;6:30163947 - 30163949

 large_intestine;盲肠 癌;腺癌 删除——在坐标系

c.118C > T;p.L40F;6:30163802 - 30163802

 胸膜 pulmonary_blastoma 替换-错义

c.385C > T;p.R129C;6:30167179 - 30167179

 皮肤 malignant_melanoma 替换-错义

c.385C > T;p.R129C;6:30167179 - 30167179

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.1389G >;p.L463L;6:30172340 - 30172340

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-编码沉默

c.562C > T;p.L188L;6:30168384 - 30168384

 皮肤 malignant_melanoma 替换-编码沉默

c.84C >;p.T28T;6:30163768 - 30163768

 肾脏 其他;肿瘤 替换-编码沉默

c.571C > T;p.L191L;6:30168393 - 30168393

 皮肤 malignant_melanoma 替换-编码沉默

c.843C > T;p.F281F;6:30170612 - 30170612

 皮肤 malignant_melanoma 替换-编码沉默

c.1336G > T;p.G446C;6:30172287 - 30172287

 肝 癌;hepatocellular_carcinoma 替换-错义

c.393G >;p.R131R;6:30167187 - 30167187

 皮肤 malignant_melanoma 替换-编码沉默

c.1044C >;p.R348R;6:30171995 - 30171995

 large_intestine;结肠 癌;腺癌 替换-编码沉默

c.1156G >;p.V386I;6:30172107 - 30172107

 胰腺 癌 替换-错义

c.120C > T;p.L40L;6:30163804 - 30163804

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-编码沉默

c.1026G >;p.P342P;6:30171977 - 30171977

 large_intestine;结肠 癌;腺癌 替换-编码沉默

c.371A > C;p.Q124P;6:30164055 - 30164055

 前列腺癌 癌 替换-错义

c.1278G >;p.V426V;6:30172229 - 30172229

 皮肤 malignant_melanoma 替换-编码沉默

c.1253C > T;p.A418V;6:30172204 - 30172204

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.478-1G >;p。?。6:30168299 - 30168299

 骨 Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour 未知的

c.149C > T;p.S50F;6:30163833 - 30163833

 皮肤 malignant_melanoma 替换-错义

c.149C > T;p.S50F;6:30163833 - 30163833

 NS malignant_melanoma 替换-错义

c.1079G >;p.G360D;6:30172030 - 30172030

 食管 癌;腺癌 替换-错义

c.187G >;p.E63K;6:30163871 - 30163871

 皮肤 malignant_melanoma 替换-错义

c.289G > T;p.D97Y;6:30163973 - 30163973

 子宫内膜 癌;endometrioid_carcinoma 替换-错义

c.854T > C;p.L285S;6:30170982 - 30170982

 肾脏 癌;clear_cell_renal_cell_carcinoma 替换-错义

c.1202C >;p.S401Y;6:30172153 - 30172153

 肝 癌;hepatocellular_carcinoma 替换-错义

c.370C > T;p.Q124 *;6:30164054 - 30164054

 urinary_tract;膀胱 癌 替换-胡说

c.486C > T;p.I162I;6:30168308 - 30168308

 large_intestine;直肠 癌;腺癌 替换-编码沉默

c.1360G > C;p.V454L;6:30172311 - 30172311

 胰腺 pancreatic_intraepithelial_neoplasia_ (PanIN) 替换-错义

c.1360G > C;p.V454L;6:30172311 - 30172311

 胰腺 癌;ductal_carcinoma 替换-错义

c.1213G >;p.D405N;6:30172164 - 30172164

 large_intestine;结肠 癌;腺癌 替换-错义

c.141G > T;p.G47G;6:30163825 - 30163825

 卵巢 癌;serous_carcinoma 替换-编码沉默

c.751G >;p.V251M;6:30170520 - 30170520

 食道;lower_third 癌;腺癌 替换-错义

c.487G >;p.E163K;6:30168309 - 30168309

 子宫内膜 癌;endometrioid_carcinoma 替换-错义

c.301C > T;p.L101F;6:30163985 - 30163985

 皮肤 malignant_melanoma 替换-错义

c.605G > T;p.R202M;6:30168427 - 30168427

 large_intestine;结肠 癌;腺癌 替换-错义

c.355C > T;p.L119L;6:30164039 - 30164039

 皮肤 malignant_melanoma 替换-编码沉默

c.785A > G;p.K262R;6:30170554 - 30170554

 皮肤;树干 malignant_melanoma 替换-错义

c.106T > C;p.C36R;6:30163790 - 30163790

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.934G >;p.D312N;6:30171885 - 30171885

 皮肤 malignant_melanoma 替换-错义

c.793C > T;p.R265C;6:30170562 - 30170562

 large_intestine;结肠 癌;腺癌 替换-错义

c.541G > T;p.E181 *;6:30168363 - 30168363

 large_intestine;结肠 癌;腺癌 替换-胡说

c.259G >;p.G87S;6:30163943 - 30163943

 central_nervous_system;大脑 神经胶质瘤 替换-错义

c.288C > T;p.N96N;6:30163972 - 30163972

 子宫内膜 癌;endometrioid_carcinoma 替换-编码沉默

c.345C >;p.T115T;6:30164029 - 30164029

 肺 癌;腺癌 替换-编码沉默

c.85A > G;p.I29V;6:30163769 - 30163769

 肝 癌;hepatocellular_carcinoma 替换-错义

c.805A > C;p.R269R;6:30170574 - 30170574

 肺 癌;腺癌 替换-编码沉默

c.859C > T;p.H287Y;6:30170987 - 30170987

 皮肤;head_neck 癌;squamous_cell_carcinoma 替换-错义

c.85A > G;p.I29V;6:30163769 - 30163769

 large_intestine;结肠 癌;腺癌 替换-错义

c.85A > G;p.I29V;6:30163769 - 30163769

 large_intestine;结肠 癌;腺癌 替换-错义

c.229C > T;p.P77S;6:30163913 - 30163913

 皮肤 malignant_melanoma 替换-错义

c.722A > G;p.N241S;6:30169254 - 30169254

 皮肤 malignant_melanoma 替换-错义

c.289G >;p.D97N;6:30163973 - 30163973

 前列腺癌 癌 替换-错义

c.1337G >;p.G446D;6:30172288 - 30172288

 肺 癌;腺癌 替换-错义

c.112C > T;p.L38F;6:30163796 - 30163796

 皮肤 malignant_melanoma 替换-错义

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