| 一般信息|文学|表达式|监管|变体|交互 |
基本信息 |
|
|---|---|
基因身份证 |
3172年 |
的名字 |
HNF4A |
同义的 |
FRTS4 | HNF4 | HNF4a7 | HNF4a8 | HNF4a9 | HNF4alpha | MODY | MODY1 | NR2A1 | NR2A21 | TCF | TCF14;肝细胞的核因子4α,HNF4A;肝细胞的核因子4α |
定义 |
HNF4alpha10/11/12 | TCF-14 |肝核因子4α|肝细胞的核因子4α核受体亚科2组一员1 | | 14 |转录因子HNF-4转录因子 |
位置 |
20 q13.12 |
基因型 |
蛋白质编码 |
基因调控: |
上游小分子核糖核酸 转录因子 从dbPTM转录后修饰 甲基化从DiseaseMeth数据库配置文件 |
实验验证了从miRTarBase microrna(最高) |
 |
转录因子(最高) |
从数据库TransFac监管 |
|---|
| HNF-4alpha2 (h) - - > CEACAM1 (h) (DNA结合;transregulation)。 |
| HNF-4alpha3 (h) + HNF-4alpha2 (h) < = = > HNF-4alpha3 (h): HNF-4alpha2 (h)(绑定)。 |
| HNF-4alpha2 (h) + HIF-1alpha (h) < = = > HNF-4alpha2 (h): HIF-1alpha (h)(绑定) |
| HNF-4alpha2 (h) + arnt (h) < = = > HNF-4alpha2 (h): arnt (h)(绑定) |
| HNF-4alpha2 (h) - - > Pklr (r) (DNA结合)。 |
| HNF-4alpha2 (h) + islet1 (r) < = = > HNF-4alpha2 (h): islet1 (r)(绑定) |
| HNF-4alpha2 (h) + LIMK1(理科硕士)< = = > HNF-4alpha2 (h): LIMK1(理科硕士)(绑定) |
| HNF-4alpha2 (h) - - > TCF1 (h) (transactivation) |
| HNF-4alpha2 (h) - - > PPARA (h) (transactivation) |
| HNF-4alpha2 (h) - - > ins-1 (r) (transactivation) |
| HNF-4alpha2 (h) + islet1-isoform1 (r) < = = > HNF-4alpha2 (h): islet1-isoform1 (r)(绑定) |
| HNF-4alpha2 (h) - - > CYP8B1 (h) (DNA结合;transactivation)。 |
| HNF-4alpha2 (h) - - > Dio1 (m) (DNA结合;transactivation)。 |
| HNF-4alpha2 (h) - - > SLC22A6 (h) (DNA结合;transactivation)。 |
| HNF4A (h) - - > HNF-4alpha2 (h)(表达式)。 |
| HNF-4alpha1 (h) - - > CEACAM1 (h) (DNA结合;transregulation)。 |
| HNF-4alpha1 (h) + HNF-4alpha3 (h) < = = > HNF-4alpha1 (h): HNF-4alpha3 (h)(绑定)。 |
| HNF-4alpha1 (h) - - > Onecut1 (r) (DNA结合;transactivation)。 |
| HNF-4alpha1 (h) - - > PPARA (h) (DNA结合;transregulation)。 |
| HNF-4alpha1 (h) - - > LIPC (h) (DNA结合)。 |
| HNF-4alpha1 (h) + TRIP-3 (h) < = = > HNF-4alpha1 (h): TRIP-3 (h)(绑定) |
| HNF4A (h) - - > HNF-4alpha1 (h)(表达式)。 |
| HNF-4alpha4 (h) - - > CEACAM1 (h) (DNA结合;transregulation)。 |
| HNF4A (h) - - > HNF-4alpha4 (h)(表达式)。 |
| HNF-4alpha3 (h) - - > CEACAM1 (h) (DNA结合;transregulation)。 |
| HNF-4alpha3 (h) + HNF-4alpha2 (h) < = = > HNF-4alpha3 (h): HNF-4alpha2 (h)(绑定)。 |
| HNF-4alpha1 (h) + HNF-4alpha3 (h) < = = > HNF-4alpha1 (h): HNF-4alpha3 (h)(绑定)。 |
| HNF-4alpha3 (h) + islet1 (r) < = = > HNF-4alpha3 (h): islet1 (r)(绑定) |
| HNF4A (h) - - > HNF-4alpha3 (h)(表达式)。 |
| HNF-4 (h) - - > HNF-1 (r) (DNA结合)。 |
| HNF-4 (h) - - > apoCIII (h) (DNA结合)。 |
| HNF-4 (h) - - > GUCY2C (h) (DNA结合)。 |
| HNF-4 (h) +乙酰辅酶a, CBP (h) - - > HNF-4 (h) {a} +辅酶a(乙酰化作用) |
| 海关与边境保护局(h) + HNF-4 (h) < = = > CBP (h): HNF-4 (h)(绑定) |
| HNF-4 (h) - - >飞机观测(h) (DNA结合;transactivation)。 |
| HNF-4 (h) - - > Epo (h) (DNA结合;transactivation)。 |
| HNF-4 (h) - - > Cyp7a1 (r) (DNA结合;transactivation)。 |
| HNF-4 (h) - - > CYP8B1 (r) (DNA结合;transactivation)。 |
| HNF-4 (h) - - > Cyp7A (gl) (DNA结合;transactivation)。 |
| HNF-4 (h) - - > SERPINC1 (h) (DNA结合)。 |
| HNF-4 (h) - - > F10 (h) (DNA结合)。 |
| HNF-4 (h) - - > F12 (h) (DNA结合)。 |
| HNF-4 (h) - - > MST1 (h) (DNA结合;transregulation)。 |
| HNF-4 (h) - - > PPARA (h) (DNA结合)。 |
| SHBG HNF-4 (h) - > (h) (DNA结合)。 |
| HNF-4 (h) - - > CYP2C9 (h) (DNA结合;transactivation)。 |
| CYP2D6 HNF-4 (h) - > (h) (DNA结合)。 |
| HNF-4 (h) - - > F2 (h) (DNA结合)。 |
| HNF-4 (h) - - > CYP2C8 (h) (DNA结合;transactivation)。 |
| HNF-4 (h) - - > apoC-II (h) (DNA结合)。 |
| HNF4A (h) - - > HNF-4 (h)(表达式)。 |
| HNF-4alpha (h) - - > Cpt1a (r) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > F11 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > AKR1C4 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > F7 (h) (DNA结合)。 |
| HNF-4alpha (h) + Smad3 (h) < = = > HNF-4alpha (h): Smad3 (h)(绑定)。 |
| HNF-4alpha (h) + smad4 (h) < = = > HNF-4alpha (h): smad4 (h)(绑定)。 |
| PGC-1 (h) + HNF-4alpha (h) < = = > PGC-1 (h): HNF-4alpha (h)(绑定)。 |
| PGC-1 (m) + HNF-4alpha (h) < = = > PGC-1 (m): HNF-4alpha (h)(绑定)。 |
| HNF-4alpha (h) + Smad3 (h): smad4 (h) < = = > HNF-4alpha (h): Smad3 (h): smad4 (h)(绑定)。 |
| HNF-4alpha (h) - - > HMOX1 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - >们(h) (DNA结合)。 |
| HNF-4alpha (h) - - > GK (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > CYP3A4 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > CYP27A1 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > CYP8B1 (h) (DNA结合)。 |
| HNF-4alpha (h) + SREBP-2 (h) < = = > HNF-4alpha (h): SREBP-2 (h)(绑定) |
| HNF-4alpha (h) - - > TCF1 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > Cyp2a5 (m) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > LIPC (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > apoAI (h) (DNA结合;transactivation)。 |
| CYP2D6 HNF-4alpha (h) - > (h) (DNA结合)。 |
| HNF-4alpha (h) - - > apoC-II (h) (DNA结合)。 |
| 月桂酸+ HNF-4alpha (h) < = = >月桂酸:HNF-4alpha (h)(绑定) |
| 肉豆蔻酸+ HNF-4alpha (h) < = = >肉豆蔻酸:HNF-4alpha (h)(绑定) |
| 棕榈酸+ HNF-4alpha (h) < = = >棕榈酸:HNF-4alpha (h)(绑定) |
| 9 -十六碳烯酸+ HNF-4alpha (h) < = = > 9 -十六碳烯酸:HNF-4alpha (h)(绑定) |
| HNF-4alpha (h) - - > alpha1-AT (h) (DNA结合)。 |
| HNF-4alpha (h) - - >飞机观测(h) (DNA结合)。 |
| HNF-4alpha (h) - - > HNF-1 (r) (DNA结合)。 |
| HNF-4alpha (h) - - > AGT (h) (DNA结合)。 |
| HNF-4alpha (h) - - > FABP2 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > PAK7 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > SLC22A1 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > RPS6KA6 (h) (DNA结合)。 |
| HNF-4alpha (h) + ATP p38(理科硕士)——> HNF-4alpha (h) {pS158} + ADP(磷酸化) |
| HNF-4alpha (h) + ATP - ERK(理科硕士)——> HNF-4alpha (h) {p} + ADP(磷酸化) |
| HNF-4alpha (h) + ATP -物(理科硕士)——> HNF-4alpha (h) {p} + ADP(磷酸化) |
| HNF-4alpha (h) - - > HNF4A (h) (DNA结合)。 |
| HNF-4alpha (h) - - > SLC22A7 (h) (DNA结合)。 |
| HIF-1alpha (h) + HNF-4alpha (h) < = = > HIF-1alpha (h): HNF-4alpha (h)(绑定) |
| HNF-4alpha (h) + SRC-1(理科硕士)< = = > HNF-4alpha (h): SRC-1(理科硕士)(绑定) |
| HNF-4alpha (h) + prox1 (h) < = = > HNF-4alpha (h): prox1 (h)(绑定) |
| HNF-4alpha (h) + gamma-synuclein (h) < = = > HNF-4alpha (h): gamma-synuclein (h)(绑定) |
| HNF-4alpha (h) + exostosin-2 (h) < = = > HNF-4alpha (h): exostosin-2 (h)(绑定) |
| HNF-4alpha (h) + MPSK (h) < = = > HNF-4alpha (h): MPSK (h)(绑定) |
| HNF-4alpha (h) + Rad50 (h) < = = > HNF-4alpha (h): Rad50 (h)(绑定) |
| HNF-4alpha (h) + APP1 (h) < = = > HNF-4alpha (h): APP1 (h)(绑定) |
| HNF-4alpha (h) - - > NR1i3 (m) (transactivation) |
| PNRC (h) + HNF-4alpha (h) < = = > PNRC (h): HNF-4alpha (h)(绑定) |
| HNF-4alpha (h) + PNRC2 (h) < = = > HNF-4alpha (h): PNRC2 (h)(绑定) |
| HNF-4alpha (h) + ASC-2 (h) < = = > HNF-4alpha (h): ASC-2 (h)(绑定) |
| HNF-4alpha (h) + RIP140 (h) < = = > HNF-4alpha (h): RIP140 (h)(绑定) |
| HNF-4alpha (h) +轴马力(h) < = = > HNF-4alpha (h):轴马力(h)(绑定) |
| Ubc9 (h) + HNF-4alpha (h) < = = > Ubc9 (h): HNF-4alpha (h)(绑定) |
| HNF-4alpha (h) + JAB1 (h) < = = > HNF-4alpha (h): JAB1 (h)(绑定) |
| HNF-4alpha (h) - - > apoCIII (h) (DNA结合)。 |
| HNF-4alpha (h) - - > apoA-IV (h) (DNA结合)。 |
| HNF-4alpha (h) - - > Cyp7a1 (r) (DNA结合)。 |
| HNF-4alpha (h) - - > CES2 (m) (DNA结合)。 |
| 2 HNF-4alpha (h) < = = > (HNF-4alpha (h)) 2(绑定) |
| HNF-4alpha (h) - - > SLC10A1 (h) (transactivation) |
| HNF-4alpha (h) - - > Abcg5 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > ABCG8 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > Slc10a1 (r) (DNA结合)。 |
| HNF-4alpha (h) - - > Abcb4 (r) (DNA结合)。 |
| HNF-4alpha (h) - > (h)竞技场队伍(DNA结合)。 |
| HNF-4alpha (h) - - > ABCC1 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > Apoa5 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > Dio1 (m) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > ABCB4 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > Abcb4 (m) (DNA结合)。 |
| HNF-4alpha (h) - - > Abcc1 (m) (DNA结合)。 |
| HNF-4alpha (h) - - > Abcc1 (r) (DNA结合)。 |
| HNF-4alpha (h) - - > PLCB1 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > TRPC1 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > Plcb1 (r) (DNA结合)。 |
| HNF-4alpha (h) - - > Trpc1 (r) (DNA结合)。 |
| GR (h) + HNF-4alpha (h) < = = > HNF-4alpha (h): GR (h)(绑定) |
| HNF-4alpha (h) - - > Pck1 (r) (DNA结合)。 |
| HNF-4alpha (h) - - > gf (h) (DNA结合)。 |
| 体内CYP2A6基因表现HNF-4alpha (h) - > (h) (DNA结合)。 |
| HNF-4alpha (h) - - > SEPP1 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > GUCY2C (h) (DNA结合)。 |
| HNF-4alpha (h) - - > NR1I2 (h) (DNA结合;transactivation)。 |
| HNF-4alpha (h) - - > Hsd17b7 (h) (DNA结合)。 |
| HNF-4alpha (h) - - > SLC28A1 (h) (DNA结合;transactivation)。 |
| HNF4A (h) - - > HNF-4alpha (h)(表达式)。 |
| HNF4A (h) - - > HNF-4alpha7 (h)(表达式)。 |
转录后修饰(最高) |
|||
位置(AA) |
天车类型 |
文学 |
数据库 |
|---|---|---|---|
| 429年 | Phosphothreonine(通过相似)。 | Swiss-Prot 53.0 | |
| 432年 | Phosphothreonine(通过相似)。 | Swiss-Prot 53.0 | |
| 133年 | 磷酸丝氨酸 | 16351573 | 磷质。榆树6.0 |
| 134年 | 磷酸丝氨酸 | 16351573 | 磷质。榆树6.0 |
| 158年 | 磷酸丝氨酸(MAPK11) | 16351573 | 磷质。榆树6.0 |
| 181年 | 磷酸丝氨酸 | 16351573 | 磷质。榆树6.0 |
| 460年 | Phosphothreonine | 16351573 | 磷质。榆树6.0 |
甲基化概要(最高) |
||
染色体 |
位置 |
源 |
|---|---|---|
chr20 |
子:42416355 - 42418355 | GSE27584 |
chr20 |
子:42416355 - 42418355 | GSE27584 |
chr20 |
子:42416355 - 42418355 | GSE27584 |
chr20 |
子:42461838 - 42463838 | GSE27584 |
chr20 |
子:42461838 - 42463838 | GSE27584 |
chr20 |
子:42461838 - 42463838 | GSE27584 |
chr20 |
子:42461838 - 42463838 | e -大地测量学- 20553 |
chr20 |
子:42416355 - 42418355 | e -大地测量学- 20553 |
chr20 |
子:42416355 - 42418355 | e -大地测量学- 20553 |
chr20 |
子:42416355 - 42418355 | e -大地测量学- 20553 |
chr20 |
子:42461838 - 42463838 | e -大地测量学- 20553 |
chr20 |
子:42461838 - 42463838 | e -大地测量学- 20553 |