| 一般信息|文学|表达式|监管|变体|交互 |
基本信息 |
|
|---|---|
基因身份证 |
6502年 |
的名字 |
SKP2 |
同义的 |
kinase-associated FBL1 | FBXL1 | FLB1 |下岗通知;s阶段蛋白质2,E3泛素蛋白连接酶;SKP2; s阶段kinase-associated蛋白质2,E3泛素蛋白连接酶 |
定义 |
CDK2 /细胞周期素关联的蛋白质下岗通知|盒/ LRR-repeat蛋白质kinase-associated 1 | s阶段kinase-associated蛋白2(下岗通知)| 2 | s阶段p45skp2 |
位置 |
5 p13 |
基因型 |
蛋白质编码 |
基因调控: |
上游小分子核糖核酸 转录因子 从dbPTM转录后修饰 甲基化从DiseaseMeth数据库配置文件 |
实验验证了从miRTarBase microrna(最高) |
 |
转录因子(最高) |
从数据库TransFac监管 |
|---|
| Cks1 (h) + Skp2 (h) < = = > Cks1 (h): Skp2 (h)(绑定) |
| cyclinE (h) + Skp2 (h) < = = > cyclinE (h): Skp2 (h)(绑定) |
| p27Kip1 (h) {pS10} {pT187} {pT198} + Skp2 (h) < = = > p27Kip1 (h) {pS10} {pT187} {pT198}: Skp2 (h)(绑定) |
| Fzr (h) + Skp2 (h) < = = > Fzr (h): Skp2 (h)(绑定) |
| Skp2 (h) + n泛素(vs) E1 (vs) E2-C (h), cyclosome (x): Fzr (h) - - > Skp2 (h){乌兰巴托(n)}(泛素化) |
| Skp2 (h) + Wee1 (h) < = = > Skp2 (h): Wee1 (h)(绑定) |
| Skp1 (h) + Skp2 (h) < = = > Skp1 (h): Skp2 (h)(绑定) |
| cyclinA (h): Cdk2 (h) + Skp2 (h) < = = > cyclinA (h): Cdk2 (h): Skp2 (h)(绑定) |
| Skp2 (h) + ATP - cyclinA (b): Cdk2 (x) {pT160} - - > Skp2 (h) {pS76} + ADP(磷酸化) |
| cyclinA (h) + Skp2 (h) < = = > cyclinA (h): Skp2 (h)(绑定) |
| E47 (h) {p} + Skp2 (h) < = = > E47 (h) {p}: Skp2 (h)(绑定) |
| Skp2 (h) + Skp1 (h) + E47 (h) < = = > Skp2 (h): Skp1 (h): E47 (h)(绑定) |
| p27Kip1 (h) + Skp2 (h) < = = > p27Kip1 (h): Skp2 (h)(绑定) |
| 原癌基因(h) + Skp2 (h) < = = >原癌基因(h): Skp2 (h)(绑定) |
| FOXO1A (h) + Skp2 (h) < = = > FOXO1A (h): Skp2 (h)(绑定) |
| Skp2 (h) + FOXO1A(理科硕士)< = = > Skp2 (h): FOXO1A(理科硕士)(绑定) |
| BRCA2 (h) + Skp2 (h) < = = > BRCA2 (h): Skp2 (h)(绑定) |
| Skp2 (h) - - >蛋白质残留(退化) |
| Tob1 (h) + Skp2 (h) < = = > Tob1 (h): Skp2 (h)(绑定) |
| Skp2 (h) / p27Kip1 (h)(丰度的减少) |
| Skp2 (h) + CUL4A(理科硕士)< = = > Skp2 (h): CUL4A(理科硕士)(绑定) |
| Skp2 (h) - - > p53 (h) {aceK382}(乙酰化作用的减少) |
| Skp2 (h) + p300 (h) < = = > Skp2 (h): p300 (h)(绑定) |
| Skp2 (h) + p300(理科硕士)< = = > Skp2 (h): p300(理科硕士)(绑定) |
| AKT-1(理科硕士)+ Skp2 (h) < = = > AKT-1(理科硕士):Skp2 (h)(绑定) |
| Skp2 (h) + ATP - AKT-1(理科硕士)——> Skp2 (h) {pS72} + ADP(磷酸化) |
| Skp2 (h) + ATP - AKT-1 (h) - - > Skp2 (h) {p} + ADP(磷酸化) |
| Skp2 (h) + ATP - AKT-2 (m) - - > Skp2 (h) {pS72} + ADP(磷酸化) |
| CKI-epsilon (h) + Skp2 (h) < = = > CKI-epsilon (h): Skp2 (h)(绑定) |
| Skp2 (h) + CKI-delta (h) < = = > Skp2 (h): CKI-delta (h)(绑定) |
| Skp2 (h) + ATP -长江基建(h) - > Skp2 (h) {pS75} + ADP(磷酸化) |
| Skp2 (h) + ATP - - > Skp2 (h) {pS64} + ADP(磷酸化) |
| Skp2 (h) + 2 ATP - - > Skp2 (h) {pS72} {pS75} + 2 ADP(磷酸化) |
| Skp2 (h) + Fzr1(理科硕士)< = = > Skp2 (h): Fzr1(理科硕士)(绑定) |
| Skp2 (h) + importin-alpha(理科硕士)< = = > Skp2 (h): importin-alpha(理科硕士)(绑定) |
| Skp2 (h) - - > Skp2 (h)(移位) |
| AKT-1 (h) + Skp2 (h) < = = > AKT-1 (h): Skp2 (h)(绑定) |
| Skp2 (h) + ATP - AKT-1 (h) - - > Skp2 (h) {pS72} + ADP(磷酸化) |
| 14-3-3beta (h) + Skp2 (h) < = = > 14-3-3beta (h): Skp2 (h)(绑定) |
| Skp2 (h) + ATP - AKT-1 (h) - - > Skp2 (h) {pT21} + ADP(磷酸化) |
| Twa1 (h) + Skp2 (h) < = = > Twa1 (h): Skp2 (h)(绑定) |
| SKP2 (h) - - > SKP2 (h)(表达式)。 |
| HDAC (h) / Skp2 (h)(丰度的减少) |
| AKT-1 (h) {pS473} - - > Skp2 (h)(丰度的增加) |
| AKT-1 (h) - - > Skp2 (h)(丰度的增加) |
| PTEN (h) / Skp2 (h)(丰度的减少) |
| igf - 1 (h) - - > Skp2 (h)(丰度的增加) |
| Fzr (h) / Skp2 (h)(丰度的减少) |
| 长江基建(h) - - > Skp2 (h)(丰度的增加) |
| Skp2 (h) - - > Skp2 (h)(移位) |
| DDB1 (h) / Skp2 (h)(丰度的减少) |
| 钙粘蛋白(h) / Skp2 (h)(丰度的减少) |
| BRCA2 (h) +泛素(h)——Skp2 (h) - - > BRCA2 (h){乌兰巴托}(泛素化) |
| Cdk2 (h) + ATP - CAK (m) - - > Cdk2 (h) {pT160} + ADP(磷酸化) |
| Cdk2 (h) + ATP - Wee1 (h) - - > Cdk2 (h) {pY15} + ADP(磷酸化) |
| Cul-1 (h) + Skp1 (h) + Skp2-alpha (h) < = = > Cul-1 (h): Skp1 (h): Skp2-alpha (h)(绑定) |
| SKP2 (h) - - > Skp2-alpha (h)(表达式)。 |
| SKP2 (h) - - > Skp2-beta (h)(表达式)。 |
| SKP2 (h) - - > skp2-gamma (h)(表达式)。 |
转录后修饰(最高) |
|||
位置(AA) |
天车类型 |
文学 |
数据库 |
|---|---|---|---|
| 64年 | 磷酸丝氨酸。 | Swiss-Prot 53.0 | |
| 64年 | 磷酸丝氨酸 | 17081983 | 磷质。榆树6.0 |
甲基化概要(最高) |
||
染色体 |
位置 |
源 |
|---|---|---|
chr5 |
子:36186446 - 36188446 | GSE27584 |
chr5 |
子:36186446 - 36188446 | GSE27584 |