Centers

Eight Research Centers are currently in operation at the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, along with several core facilities. Although senior investigators and their associates pursue their individual research goals, there are thematic approaches the different laboratories have in common.

Current Centers:

Cardiovascular Genetic Researchstudies heart disease, stroke, and atherosclerosis.

Hans J. Müller-Eberhard and Irma Gigli Center for Immunology and Autoimmune Diseasesstudies allergies, autoimmunity, asthma, infectious lung disease, skin, and kidney diseases.

Human Geneticsaddresses a range of diseases including heart disease, stroke, hypertension, diabetes, atherosclerosis, and cerebrovascular disorders.

代谢和退化性疾病关注noninsulin-dependent diabetes, the most common form of the disease affecting our population today. By investigating the genes responsible for risk factors such as obesity, high blood pressure and high cholesterol, we may provide physicians with the new tools to help diagnose and treat diabetes long before debilitating complications can arise, or even before the disease itself can strike.

Molecular Imagingdevelops and engineers new imaging instrumentation, algorithms, and agents for in vivo molecular imaging in small animals. The Center uses in vivo imaging of unique animal models to answer key biological questions of collaborators. It also focuses upon translating scientific discoveries and new imaging approaches into the clinic such as the current trials of for near-infrared fluorescence lymphatic imaging and non-invasive PET and optical imaging for nodal staging of cancer.

Center for Stem Cell and Regenerative Medicineexplores the mechanisms behind stem cell self-renewal and differentiation with plans to expand current studies to develop stem cell lines designed to benefit transplantation medicine and the regeneration of tissues, and to provide vectors for gene therapy with direct implications for the treatment of a wide range of chronic diseases.

  • Senator Lloyd and B.A. Bentsen Center for Stroke Research促进研究与协作,导beplay苹果手机能用吗致预防中风,这是一种影响无数个人和家庭的医学问题。在美国,每年有四分之三的一百万个新的或经常性的中风,研究对于更好地理解,治疗和帮助人们避免中风至关重要。beplay苹果手机能用吗beplay苹果手机能用吗参与本恩森中心的研究人员 - 包括干细胞疗法,中风的遗传预测因子,诱发的低温/冬眠,血管系统的分子成像等领域,随着中心向前的前进,将对医疗领域产生巨大影响。

Texas Therapeutics InstituteTexas Therapeutics Institute (TTI) which is jointly funded by the Texas Emerging Technology Fund (ETF) and the University of Texas (UT) is establishing research laboratories in three UT campuses: UT Health Science Center at Houston (UTHealth), UT M.D. Anderson Cancer Center (MDACC), and UT-Austin (UTA).

TTI faculties will coordinate their research activities to provide the necessary inter-institutional infrastructure to advance drug discovery and development in the State of Texas. TTI faculties will establish independent, complementary, and collaborative translational drug discovery programs.

Translational Cancer Researchstudies novel biochemical reagents and mathematical methods with which to treat futures patients with personalized medical procedures for diagnostic and therapeutic applications. Work in the center includes mathematical prediction of the optimal chemotherapy dosage based on a patient's tumor morphology, personalized aptamer targeting agents, morphology-based targeting agents, and bioinformatics. The center has state-of-art mass spectrometry equipment for both research and CLIA-certified clinical applications.