About us
使命和视野
人类遗传学中心的使命是说cover how genomic variation impacts the health of individuals, families, and populations and to apply this information to improve public health and clinical care outcomes. We achieve our mission through a commitment to teaching, service, and research. Our research focus is on the human genomic response to various contexts, such as genetic background, environment, or even the genomes of commensal or infectious organisms. Critical to our mission is the ability to understand the behavior of genes in pedigrees and populations.
人类遗传学中心将流行病学,统计学,信息学,传染病和公共政策的公共卫生学科融合并使可访问的先进遗传学研究。beplay苹果手机能用吗我们通过与德克萨斯州和世界各地的研究小组的跨学科合作来扩大我们的研究beplay苹果手机能用吗基础。我们的愿景是为了改善和维持所有个人的健康,不要留下任何遗传石材。
Center objectives
- Train genetic investigators in molecular and cellular biology and the management, use, and analysis of familial and population-oriented data.
- Provide educational and research opportunities for doctoral students and post-doctoral fellows through employment on externally derived research funds.
- Understand the contributions of genetic factors to those common diseases that account for most of the mortality in the public health context.
- 了解影响人类基因组自然发生变化的模式的力,以及如何利用这些模式来理解人类疾病。
- 继续通过与其他研究小组的跨学科合作来扩大我们的研究基础beplay苹果手机能用吗德克萨斯医疗中心, in particular, those located in The University of Texas Health Science Center at Houston (UTHealth) School of Public Health andMcGovern Medical School.
- Seek external support to maintain state-of-the-art laboratory and computing equipment which is essential to our research.
A legacy of collaboration
人类遗传学中心于1994年9月1日在公共卫生学院内成立。该中心代表了位于德克萨斯大学生物医学科学研究生院的两个长期研究中心的合并,现在称为MD Anderson Uthealth MDbeplay苹果手机能用吗研究所。研究中心beplay苹果手机能用吗由威廉·舒尔(William J.世界卫生组织as a collaborating center for the investigation of the genetics of common disease.
目前,资助的研究项目着重于常见疾病,例beplay苹果手机能用吗如心血管疾病,糖尿病,高血压,肥胖和眼部疾病。所有这些都被证明具有很强的遗传成分,但是涉及的基因数量,其位置,产生风险的突变和相互作用尚未解决。
我们的研beplay苹果手机能用吗究兴趣
中心教师积极参与研究,从扫描人类基因组的糖尿病和高血压基因到表征眼部疾病的特异性beplay苹果手机能用吗突变,再到建立疾病基因遗传变异的进化动力学。该中心还参与了对DNA测试的法医实用性的评估,建立用于研究的国家DNA测试数据库以及用于遗传性眼部疾病的分子诊断的实验室(与部门有关beplay苹果手机能用吗麦戈文医学院的眼科)。除国际和国际努力外,该中心还自1981年以来在得克萨斯州里奥格兰德市维持了一个现场站,以促进德克萨斯州墨西哥裔美国人人口中普通疾病问题的调查。
资金
资金of our research comes from external sources including the国家al Institutes of Health,American Heart Association,American Diabetes Association,打击盲目的基础,国立司法学院, 和other philanthropic support.
Areas of expertise
- Bioinformatics
- Chronic diseases in Mexican-Americans
- 计算生物学
- 计算基因组学
- Diabetes
- DNA variation among and within populations and how these patterns evolved
- Genes and mutations causing retinal diseases
- Genetic epidemiology
- Genetics of cardiovascular disease
- 基因组变异
- 全基因组联系和关联分析
- 基因分型和DNA测序
- Impact of gene variation on individual, family and population health
- Locating and characterizing genes underlying common chronic diseases
- 分子进化
- Pharmacogenetics
- 人口遗传学理论
- Quantitative genetics
- Retinal pathophysiology
- 人类疾病的统计和计算方法
- Statistical methods for DNA sequence analyses
当前重点领域
- Understanding the genetic basis of common and complex diseases including cardiovascular disease, stroke, diabetes, birth defects, and retinal degeneration.
- Mapping the influence of genetics across the course of life from conception to old age.
- Elucidating gene-gene and gene-environment interaction.
- 确定我们的基因组与我们暂时或整个生命周期“托管”的生物之间的相互作用/敏感性。
- 阐明影响人类基因组自然发生变异模式的力。
- 将遗传发现转化为预防,治疗和精度健康。
- 高级计算工具用于遗传分析的开发和应用,包括在基于云的计算环境中托管的工具。
基因组学和生物信息学证书
Certificates for degree-seeking and non-degree seeking students
通过学习如何通过Uthealth公共卫生学院的基因组学和生物信息学证书来识别,分析和集成基因组和高维的多摩变数据和个性化健康来扩展知识。
Enhance your education with a graduate certificate in genomics and bioinformatics. The certificate is intended for professionals in academic, clinical and research settings who are now or soon to be faced with complex genomic and multi-omic data.
参加该计划的学生,临床医生和研究人员将配备竞争和领导beplay苹果手机能用吗基因组科学所需的独特技能。这些通过一组结构化课程获得的技能将帮助学生了解人类基因组学和生物信息学的进步,以便它们可以运用这种知识来改善公共卫生并预防疾病。
在线课程可用。有关更多信息,请与Jr Bright,Academic and Andissions Advisor联系Jr.f.bright@uth.tmc.edu。
项目和子组
人遗传学中心实验室
The Human Genetics Center Laboratory utilizes the latest genomic technology to understand the etiology of many common chronic diseases in human populations. Using contemporary scientific methods to facilitate the progress of future genomic research, the laboratory examines the elucidation of the interactions between genes and the environment and translates these findings into precision medicine initiatives to help guide decisions regarding the prevention, diagnosis, and treatment of disease.
该实验室提供了最先进的设备,以在许多方法中进行分子遗传学研究和专业知识的当前方法,用于基因分型和阶段跨越低吞吐量的能力。beplay苹果手机能用吗所有这些都可以量身定制以满足您的个人项目目标。通常会执行DNA和RNA提取,从几个基于人群的大型项目中的数十万个样本进行等分和管理。
For more information on the HGC Laboratory and an overview of services offered, please visit the laboratory’s website这里。
Community Outreach Biorepository
生物座席是一种存储生物材料(生物测量)的设施,以供未来的研究用途。beplay苹果手机能用吗UT医师和研究人员正在与心胸和血管手beplay苹果手机能用吗术系合作开发生物座席,并敢于C.A.R.E.,以筛查患者的心血管疾病。唾液存储并用于收集遗传信息。
为了参与您的生物测量和健康信息的收集,我们将:
- Answer your questions about the biorepository
- 要求您签署知情同意书以参加
- 收集1/2茶匙唾液
- Label your biospecimens with a barcode that does not contain your personal information (a process called de-identification)
To protect your confidentiality, we will:
- Share de-identified biospecimens and data that do not link back to you with researchers inside and outside of UTHealth (upon approval from an internal review board that protects the rights of human subjects)
- 在需要时在公共国家数据库中共享取消识别数据
- Protect your information in accordance with federal laws that make it illegal to use your genetic information to discriminate against you for health insurance coverage and employment (GINA):http://www.ginahelp.org/
您可以控制生物测量发生的事情,并可能随时选择退出参加生物座席。
我们的希望是,您对生物措施的贡献将使研究人员能够发现遗传危险因素,这些遗传危险因素将允许早期危险检测血管疾病,从而改善了个人的生活质量beplay苹果手机能用吗和治疗。捐赠给生物位是可选的。
For more information, please contact the Human Genetics Center Lab atHGC_Lab@uth.tmc.edu。
联系我们
Mailing address
Human Genetics Center
P.O. Box 20186
Houston, Texas 77225
电话
电话:713.500.9800
传真:713.500.0900